A comparison of landmark methods and time-dependent ROC methods to evaluate the time-varying performance of prognostic markers for survival outcomes by Aasthaa Bansal, Patrick J. Heagerty

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Analysis of multiple-period group randomized trials: random coefficients model or repeated measures ANOVA? by Jonathan C. Moyer, Patrick J. Heagerty, David M. Murray

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Protocol for a sequential, multiple assignment, randomised trial to test the effectiveness of message-based psychotherapy for depression compared with telepsychotherapy by Patrick J Heagerty, Patricia Arean, Derrick Hull, Michael D Pullmann

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Power and sample size calculation for stepped-wedge designs with discrete outcomes by Fan Xia, James P. Hughes, Emily C. Voldal, Patrick J. Heagerty

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Appendicular Lean Mass, Grip Strength, and the Development of Knee Osteoarthritis and Knee Pain Among Older Adults by James S. Andrews, Laura S. Gold, Michael Nevitt, Patrick J. Heagerty, Peggy M. Cawthon

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The impact of COVID-19 on pragmatic clinical trials: lessons learned from the NIH Health Care Systems Research Collaboratory by Emily C. O’Brien, Jeremy Sugarman, Kevin P. Weinfurt, Eric B. Larson, Patrick J. Heagerty, Adrian F. Hernandez, Lesley H. Curtis

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Predicting decompression surgery by applying multimodal deep learning to patients’ structured and unstructured health data by Chethan Jujjavarapu, Pradeep Suri, Vikas Pejaver, Janna Friedly, Laura S. Gold, Eric Meier, Trevor Cohen, Sean D. Mooney, Patrick J. Heagerty, Jeffrey G. Jarvik

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Diffusion Tensor Imaging Changes Do Not Affect Long-Term Neurodevelopment following Early Erythropoietin among Extremely Preterm Infants in the Preterm Erythropoietin Neuroprotecti... by Janessa B. Law, Bryan A. Comstock, Todd L. Richards, Christopher M. Traudt, Thomas R. Wood, Dennis E. Mayock, Patrick J. Heagerty, Sandra E. Juul

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Early Biomarkers of Hypoxia and Inflammation and Two-Year Neurodevelopmental Outcomes in the Preterm Erythropoietin Neuroprotection (PENUT) Trial by Thomas R. Wood, Pratik Parikh, Bryan A. Comstock, Janessa B. Law, Theo K. Bammler, Karl C. Kuban, Dennis E. Mayock, Patrick J. Heagerty, Sandra Juul, MD, PhD

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Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants by Abhishek Pratap, Elias Chaibub Neto, Phil Snyder, Carl Stepnowsky, Noémie Elhadad, Daniel Grant, Matthew H. Mohebbi, Sean Mooney, Christine Suver, John Wilbanks, Lara Mangravite, Patrick J. Heagerty, Pat Areán, Larsson Omberg

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Genetic and nongenetic sources of variation in phospholipid transfer protein activity[S] by Gail P. Jarvik, Ramakrishnan Rajagopalan, Elisabeth A. Rosenthal, Gertrud Wolfbauer, Laura McKinstry, Aditya Vaze, John Brunzell, Arno G. Motulsky, Deborah A. Nickerson, Patrick J. Heagerty, Ellen M. Wijsman, John J. Albers

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The Flares of Low back pain with Activity Research Study (FLAReS): study protocol for a case-crossover study nested within a cohort study by Pradeep Suri, Adrienne D. Tanus, Nikki Torres, Andrew Timmons, Bianca Irimia, Janna L. Friedly, Anna Korpak, Clinton Daniels, Daniel Morelli, Paul W. Hodges, Nathalia Costa, Melissa A. Day, Patrick J. Heagerty, Mark P. Jensen

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TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease by Christopher S. Carlson, Patrick J. Heagerty, Thomas S. Hatsukami, Rebecca J. Richter, Jane Ranchalis, Julieann Lewis, Tamara J. Bacus, Laura A. McKinstry, Gerard D. Schellenberg, Mark Rieder, Deborah Nickerson, Clement E. Furlong, Alan Chait, Gail P. Jarvik

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The Lumbar Stenosis Prognostic Subgroups for Personalizing Care and Treatment (PROSPECTS) study: protocol for an inception cohort study by Sean D. Rundell, Ayumi Saito, Eric N. Meier, Stephanie T. Danyluk, Jeffrey G. Jarvik, Kelley Seebeck, Janna L. Friedly, Patrick J. Heagerty, Sandra K. Johnston, Monica Smersh, Maggie E. Horn, Pradeep Suri, Amy M. Cizik, Adam P. Goode

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Effectiveness of spinal manipulation and biopsychosocial self-management compared to medical care for low back pain: a randomized trial study protocol by Gert Bronfort, Anthony Delitto, Michael Schneider, Patrick J. Heagerty, Roger Chou, John Connett, Roni Evans, Steven George, Ronald M. Glick, Carol Greco, Linda Hanson, Francis Keefe, Brent Leininger, John Licciardone, Christine McFarland, Eric Meier, Craig Schulz, Dennis Turk

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Broadening the reach of the FDA Sentinel system: A roadmap for integrating electronic health record data in a causal analysis framework by Rishi J. Desai, Michael E. Matheny, Kevin Johnson, Keith Marsolo, Lesley H. Curtis, Jennifer C. Nelson, Patrick J. Heagerty, Judith Maro, Jeffery Brown, Sengwee Toh, Michael Nguyen, Robert Ball, Gerald Dal Pan, Shirley V. Wang, Joshua J. Gagne, Sebastian Schneeweiss

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A common VLDLR polymorphism interacts with APOE genotype in the prediction of carotid artery disease risks⃞ by Dana C. Crawford, Alex S. Nord, Michael D. Badzioch, Jane Ranchalis, Laura A. McKinstry, Magdalena Ahearn, Caterina Bertucci, Cynthia Shephard, Michelle Wong, Mark J. Rieder, Gerard D. Schellenberg, Deborah A. Nickerson, Patrick J. Heagerty, Ellen M. Wijsman, Gail P. Jarvik

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Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Op... by Francis P Wilson, Edward R Melnick, Hyung Paek, Gail D’Onofrio, Daniella Meeker, Patrick J Heagerty, Carol Oladele, Mucio Kit Delgado, Richard Andrew Taylor, Mark S Iscoe, Carolina Diniz Hooper, Deborah R Levy, Laurel Buchanan, James Dziura, Daniel F Sarpong, Jason Hoppe

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Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis by Djillali Annane, Jean-Paul Mira, Lorraine B. Ware, Anthony C. Gordon, Charles J. Hinds, David C. Christiani, Jonathan Sevransky, Kathleen Barnes, Timothy G. Buchman, Patrick J. Heagerty, Robert Balshaw, Nadia Lesnikova, Karen de Nobrega, Hugh F. Wellman, Mauricio Neira, Alexandra D. J. Mancini, Keith R. Walley, James A. Russell

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Pragmatic clinical trials embedded in healthcare systems: generalizable lessons from the NIH Collaboratory by Kevin P. Weinfurt, Adrian F. Hernandez, Gloria D. Coronado, Lynn L. DeBar, Laura M. Dember, Beverly B. Green, Patrick J. Heagerty, Susan S. Huang, Kathryn T. James, Jeffrey G. Jarvik, Eric B. Larson, Vincent Mor, Richard Platt, Gary E. Rosenthal, Edward J. Septimus, Gregory E. Simon, Karen L. Staman, Jeremy Sugarman, Miguel Vazquez, Douglas Zatzick, Lesley H. Curtis

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