Abstract 85: Somatic MAP2K1 Mutations in Arteriovenous Malformation Constitutively Activate the RAS/MAPK Pathway by Jeremy A. Goss, MD, Patrick J. Smits, PhD, Mohammed H. Alomari, MD, Arin K. Greene, MD, MMSc

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75. Trametinib Prevents Formation of Vascular Lesions in a MAP2k1-p.K57N Arteriovenous Malformation Mouse Model by Patrick J. Smits, PhD, Yu Sheng Cheng, MD, Michal Ad, MD, Mattew Vivero, MD, Arin Greene, MD

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QS17. Endothelial MAP2K1 Mutation Causes Abnormal Vascular Development in Inducible Mouse Strain by Christopher L. Sudduth, MD, Patrick J. Smits, PhD, Matthew P. Vivero, MD, Yu Sheng Cheng, BS, Arin K. Greene, MD

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147. MAP2K1 Mutant Murine Model Recapitulates Human Cutaneous Arteriovenous Malformation by Michal Ad, MD, Yu Sheng Cheng, BS, Matthew P. Vivero, MD, Patrick J. Smits, PhD, Arin K. Greene, MD, MMSc

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13. Generation of a Conditional Gnaq Mutant Mouse Model of Capillary Malformation by Patrick J. Smits, PhD, Christopher Sudduth, MD, Matthew P. Vivero, MD, YuSheng Cheng, BA, Michal Ad, MD, Arin AK Greene, MD

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