Growth condition dependency is the major cause of non-responsiveness upon genetic perturbation. by Saman Amini, Frank C P Holstege, Patrick Kemmeren

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An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions by Wim J. de Jonge, Mariël Brok, Patrick Kemmeren, Frank C.P. Holstege

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Genome‐wide off‐rates reveal how DNA binding dynamics shape transcription factor function by Wim J de Jonge, Mariël Brok, Philip Lijnzaad, Patrick Kemmeren, Frank CP Holstege

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Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology by Ianthe A. E. M. van Belzen, Alexander Schönhuth, Patrick Kemmeren, Jayne Y. Hehir-Kwa

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The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interact... by Saman Amini, Annika Jacobsen, Olga Ivanova, Philip Lijnzaad, Jaap Heringa, Frank C P Holstege, K Anton Feenstra, Patrick Kemmeren

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Epistatic relationships reveal the functional organization of yeast transcription factors by Jiashun Zheng, Joris J Benschop, Michael Shales, Patrick Kemmeren, Jack Greenblatt, Gerard Cagney, Frank Holstege, Hao Li, Nevan J Krogan

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A systematic analysis of genetic interactions and their underlying biology in childhood cancer by Josephine T. Daub, Saman Amini, Denise J. E. Kersjes, Xiaotu Ma, Natalie Jäger, Jinghui Zhang, Stefan M. Pfister, Frank C. P. Holstege, Patrick Kemmeren

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The role of Ctk1 kinase in termination of small non-coding RNAs. by Tineke L Lenstra, Agnieszka Tudek, Sandra Clauder, Zhenyu Xu, Spyridon T Pachis, Dik van Leenen, Patrick Kemmeren, Lars M Steinmetz, Domenico Libri, Frank C P Holstege

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Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease by Marieke Visscher, Sasha De Henau, Mattheus H.E. Wildschut, Robert M. van Es, Ineke Dhondt, Helen Michels, Patrick Kemmeren, Ellen A. Nollen, Bart P. Braeckman, Boudewijn M.T. Burgering, Harmjan R. Vos, Tobias B. Dansen

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Trecode: A FAIR Eco-System for the Analysis and Archiving of Omics Data in a Combined Diagnostic and Research Setting by Hindrik HD Kerstens, Jayne Y Hehir-Kwa, Ellen van de Geer, Chris van Run, Shashi Badloe, Alex Janse, John Baker-Hernandez, Sam de Vos, Douwe van der Leest, Eugène TP Verwiel, Bastiaan BJ Tops, Patrick Kemmeren

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Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS by Ianthe A. E. M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Lennart Kester, Jan J. Molenaar, Jules Meijerink, Jarno Drost, Weng Chuan Peng, Hindrik H. D. Kerstens, Bastiaan B. J. Tops, Frank C. P. Holstege, Patrick Kemmeren, Jayne Y. Hehir-Kwa

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Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia by Willem K. Smits, Carlo Vermeulen, Rico Hagelaar, Shunsuke Kimura, Eric M. Vroegindeweij, Jessica G.C.A.M. Buijs-Gladdines, Ellen van de Geer, Marjon J.A.M. Verstegen, Erik Splinter, Simon V. van Reijmersdal, Arjan Buijs, Niels Galjart, Winfried van Eyndhoven, Max van Min, Roland Kuiper, Patrick Kemmeren, Charles G. Mullighan, Wouter de Laat, Jules P.P. Meijerink

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Molecular Characterization Reveals Subclasses of 1q Gain in Intermediate Risk Wilms Tumors by Ianthe A. E. M. van Belzen, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Sam de Vos, John Baker-Hernandez, Alissa Groenendijk, Ronald de Krijger, Hindrik H. D. Kerstens, Jarno Drost, Marry M. van den Heuvel-Eibrink, Bastiaan B. J. Tops, Frank C. P. Holstege, Patrick Kemmeren, Jayne Y. Hehir-Kwa

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Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes by Michael T Meister, Marian J A Groot Koerkamp, Terezinha deSouza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc vanTuil, Rutger R G Knops, Sheila Terwisscha vanScheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M vanNoesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van deWetering, Ruben vanBoxtel, Jarno Drost, Frank C P Holstege

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