Methods of Randomization of Large Files with High Volatility by Patrick C. Mitchell, Thomas K. Burgess

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A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection by Jessie Kulsuptrakul, Elizabeth A Turcotte, Michael Emerman, Patrick S Mitchell

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Hypoxemia in patients with COPD: cause, effects, and disease progression by Brian D Kent, Patrick D Mitchell, Walter T McNicholas

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Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction. by Patrick S Mitchell, Janet M Young, Michael Emerman, Harmit S Malik

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Clarifying SABA overuse: Translating Canadian Thoracic Society guidelines into clinical practice by Anne K. Ellis, Vanessa Foran, Alan Kaplan, Patrick D. Mitchell

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Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation. by Joseph Chavarría-Smith, Patrick S Mitchell, Alvin M Ho, Matthew D Daugherty, Russell E Vance

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Diverse viral proteases activate the NLRP1 inflammasome by Brian V Tsu, Christopher Beierschmitt, Andrew P Ryan, Rimjhim Agarwal, Patrick S Mitchell, Matthew D Daugherty

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Effective Asthma Management: Is It Time to Let the AIR out of SABA? by Alan Kaplan, Patrick D. Mitchell, Andrew J. Cave, Remi Gagnon, Vanessa Foran, Anne K. Ellis

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Therapeutic interventions in severe asthma by Giorgio Walter Canonica, Gianenrico Senna, Patrick D. Mitchell, Paul M. O’Byrne, Giovanni Passalacqua, Gilda Varricchi

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Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome by Abby R. Kroken, Keith A. Klein, Patrick S. Mitchell, Vincent Nieto, Eric J. Jedel, David J. Evans, Suzanne M. J. Fleiszig

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NAIP–NLRC4-deficient mice are susceptible to shigellosis by Patrick S Mitchell, Justin L Roncaioli, Elizabeth A Turcotte, Lisa Goers, Roberto A Chavez, Angus Y Lee, Cammie F Lesser, Isabella Rauch, Russell E Vance

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Severe SARS-CoV-2 Infection in a Cat with Hypertrophic Cardiomyopathy by Francisco R. Carvallo, Mathias Martins, Lok R. Joshi, Leonardo C. Caserta, Patrick K. Mitchell, Thomas Cecere, Sandy Hancock, Erin L. Goodrich, Julia Murphy, Diego G. Diel

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Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. by Stacia K Wyman, Rachael K Parkin, Patrick S Mitchell, Brian R Fritz, Kathy O'Briant, Andrew K Godwin, Nicole Urban, Charles W Drescher, Beatrice S Knudsen, Muneesh Tewari

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Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. by Heather H Cheng, Patrick S Mitchell, Evan M Kroh, Alexander E Dowell, Lisly Chéry, Javed Siddiqui, Peter S Nelson, Robert L Vessella, Beatrice S Knudsen, Arul M Chinnaiyan, Kenneth J Pienta, Colm Morrissey, Muneesh Tewari

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One Stomatal Model to Rule Them All? Toward Improved Representation of Carbon and Water Exchange in Global Models by Manon E. B. Sabot, Martin G. De Kauwe, Andy J. Pitman, Belinda E. Medlyn, David S. Ellsworth, Nicolas K. Martin‐StPaul, Jin Wu, Brendan Choat, Jean‐Marc Limousin, Patrick J. Mitchell, Alistair Rogers, Shawn P. Serbin

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Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome by Brian V. Tsu, Rimjhim Agarwal, Nandan S. Gokhale, Jessie Kulsuptrakul, Andrew P. Ryan, Elizabeth J. Fay, Lennice K. Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A. Turcotte, Sofia E. Delgado-Rodriguez, Russell E. Vance, Jennifer L. Hyde, Ram Savan, Patrick S. Mitchell, Matthew D. Daugherty

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Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome. by Brian V Tsu, Rimjhim Agarwal, Nandan S Gokhale, Jessie Kulsuptrakul, Andrew P Ryan, Elizabeth J Fay, Lennice K Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A Turcotte, Sofia E Delgado-Rodriguez, Russell E Vance, Jennifer L Hyde, Ram Savan, Patrick S Mitchell, Matthew D Daugherty

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CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons by Gong-Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket R. Gupte, Ranen Aviner, Patrick G. Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette R. Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F. Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M. Thompson, Wah Chiu

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Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci. by Taj Azarian, Patrick K Mitchell, Maria Georgieva, Claudette M Thompson, Amel Ghouila, Andrew J Pollard, Anne von Gottberg, Mignon du Plessis, Martin Antonio, Brenda A Kwambana-Adams, Stuart C Clarke, Dean Everett, Jennifer Cornick, Ewa Sadowy, Waleria Hryniewicz, Anna Skoczynska, Jennifer C Moïsi, Lesley McGee, Bernard Beall, Benjamin J Metcalf, Robert F Breiman, P L Ho, Raymond Reid, Katherine L O'Brien, Rebecca A Gladstone, Stephen D Bentley, William P Hanage

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From People to <italic toggle="yes">Panthera</italic>: Natural SARS-CoV-2 Infection in Tigers and Lions at the Bronx Zoo by Denise McAloose, Melissa Laverack, Leyi Wang, Mary Lea Killian, Leonardo C. Caserta, Fangfeng Yuan, Patrick K. Mitchell, Krista Queen, Matthew R. Mauldin, Brittany D. Cronk, Susan L. Bartlett, John M. Sykes, Stephanie Zec, Tracy Stokol, Karen Ingerman, Martha A. Delaney, Richard Fredrickson, Marina Ivančić, Melinda Jenkins-Moore, Katie Mozingo, Kerrie Franzen, Nichole Hines Bergeson, Laura Goodman, Haibin Wang, Ying Fang, Colleen Olmstead, Colleen McCann, Patrick Thomas, Erin Goodrich, François Elvinger, David C. Smith, Suxiang Tong, Sally Slavinski, Paul P. Calle, Karen Terio, Mia Kim Torchetti, Diego G. Diel

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