Paul J. Hergenrother

Paul J. Hergenrother is an American chemist and the Kenneth L. Rinehart Jr. Endowed Chair in Natural Products chemistry at the University of Illinois Urbana-Champaign. His research focuses on the development of organic small molecules with novel biological properties such as enzyme inhibitors and activators, chemotherapeutics, and antibacterial agents. In 2008 Hergenrother was awarded the Eli Lilly Award in Biological Chemistry. Provided by Wikipedia
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  1. 1
    Using permeation guidelines to design new antibiotics—A PASsagE into Pseudomonas aeruginosa

    Using permeation guidelines to design new antibiotics—A PASsagE into Pseudomonas aeruginosa by Brett N. Cain, Paul J. Hergenrother

    Published 2024-03-01
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  2. 2
    A Phosphonate Natural Product Made by Pantoea ananatis is Necessary and Sufficient for the Hallmark Lesions of Onion Center Rot

    A Phosphonate Natural Product Made by Pantoea ananatis is Necessary and Sufficient for the Hallmark Lesions of Onion Center Rot by Alexander L. A. Polidore, Lucia Furiassi, Paul J. Hergenrother, William W. Metcalf

    Published 2021-02-01
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  3. 3
    Small-Molecule Procaspase‑3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics

    Small-Molecule Procaspase‑3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics by Rachel C. Botham, Howard S. Roth, Alison P. Book, Patrick J. Roady, Timothy M. Fan, Paul J. Hergenrother

    Published 2016-07-01
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  4. 4
    Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers

    Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers by Lisa J. Schlein, Bahaa Fadl-Alla, Holly C. Pondenis, Stéphane Lezmi, Charles G. Eberhart, Amy K. LeBlanc, Peter J. Dickinson, Paul J. Hergenrother, Timothy M. Fan

    Published 2019-02-01
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  5. 5
    Augmented Concentration of Isopentyl-Deoxynyboquinone in Tumors Selectively Kills NAD(P)H Quinone Oxidoreductase 1-Positive Cancer Cells through Programmed Necrotic and Apoptotic Mechanisms

    Augmented Concentration of Isopentyl-Deoxynyboquinone in Tumors Selectively Kills NAD(P)H Quinone Oxidoreductase 1-Positive Cancer Cells through Programmed Necrotic and Apoptotic M... by Jiangwei Wang, Xiaolin Su, Lingxiang Jiang, Matthew W. Boudreau, Lindsay E. Chatkewitz, Jessica A. Kilgore, Kashif Rafiq Zahid, Noelle S. Williams, Yaomin Chen, Shaohui Liu, Paul J. Hergenrother, Xiumei Huang

    Published 2023-12-01
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  6. 6
    A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed

    A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed by Rahul Palchaudhuri, Michael J. Lambrecht, Rachel C. Botham, Kathryn C. Partlow, Tjakko J. van Ham, Karson S. Putt, Laurie T. Nguyen, Seok-Ho Kim, Randall T. Peterson, Timothy M. Fan, Paul J. Hergenrother

    Published 2015-12-01
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  7. 7
    Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model

    Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model by David M Kranz, Edward J Roy, Preeti Sharma, Diana Rose E Ranoa, Claire P Schane, Amber N Lewis, Edward Valdez, Venkata V V R Marada, Marlies V Hager, Will Montgomery, Steven P Wolf, Karin Schreiber, Hans Schreiber, Keith Bailey, Timothy M Fan, Paul J Hergenrother

    Published 2023-05-01
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  8. 8
    Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

    Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury by Wulf Tonnus, Claudia Meyer, Christian Steinebach, Alexia Belavgeni, Anne von Mässenhausen, Nadia Zamora Gonzalez, Francesca Maremonti, Florian Gembardt, Nina Himmerkus, Markus Latk, Sophie Locke, Julian Marschner, Wenjun Li, Spencer Short, Sebastian Doll, Irina Ingold, Bettina Proneth, Christoph Daniel, Nazanin Kabgani, Rafael Kramann, Stephen Motika, Paul J. Hergenrother, Stefan R. Bornstein, Christian Hugo, Jan Ulrich Becker, Kerstin Amann, Hans-Joachim Anders, Daniel Kreisel, Derek Pratt, Michael Gütschow, Marcus Conrad, Andreas Linkermann

    Published 2021-07-01
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  9. 9
    Mitigation of SARS-CoV-2 transmission at a large public university

    Mitigation of SARS-CoV-2 transmission at a large public university by Diana Rose E. Ranoa, Robin L. Holland, Fadi G. Alnaji, Kelsie J. Green, Leyi Wang, Richard L. Fredrickson, Tong Wang, George N. Wong, Johnny Uelmen, Sergei Maslov, Zachary J. Weiner, Alexei V. Tkachenko, Hantao Zhang, Zhiru Liu, Ahmed Ibrahim, Sanjay J. Patel, John M. Paul, Nickolas P. Vance, Joseph G. Gulick, Sandeep Puthanveetil Satheesan, Isaac J. Galvan, Andrew Miller, Joseph Grohens, Todd J. Nelson, Mary P. Stevens, P Mark Hennessy, Robert C. Parker, Edward Santos, Charles Brackett, Julie D. Steinman, Melvin R. Fenner, Kirstin Dohrer, Michael DeLorenzo, Laura Wilhelm-Barr, Brian R. Brauer, Catherine Best-Popescu, Gary Durack, Nathan Wetter, David M. Kranz, Jessica Breitbarth, Charlie Simpson, Julie A. Pryde, Robin N. Kaler, Chris Harris, Allison C. Vance, Jodi L. Silotto, Mark Johnson, Enrique Andres Valera, Patricia K. Anton, Lowa Mwilambwe, Stephen P. Bryan, Deborah S. Stone, Danita B. Young, Wanda E. Ward, John Lantz, John A. Vozenilek, Rashid Bashir, Jeffrey S. Moore, Mayank Garg, Julian C. Cooper, Gillian Snyder, Michelle H. Lore, Dustin L. Yocum, Neal J. Cohen, Jan E. Novakofski, Melanie J. Loots, Randy L. Ballard, Mark Band, Kayla M. Banks, Joseph D. Barnes, Iuliana Bentea, Jessica Black, Jeremy Busch, Abigail Conte, Madison Conte, Michael Curry, Jennifer Eardley, April Edwards, Therese Eggett, Judes Fleurimont, Delaney Foster, Bruce W. Fouke, Nicholas Gallagher, Nicole Gastala, Scott A. Genung, Declan Glueck, Brittani Gray, Andrew Greta, Robert M. Healy, Ashley Hetrick, Arianna A. Holterman, Nahed Ismail, Ian Jasenof, Patrick Kelly, Aaron Kielbasa, Teresa Kiesel, Lorenzo M. Kindle, Rhonda L. Lipking, Yukari C. Manabe, Jade ́ Mayes, Reubin McGuffin, Kenton G. McHenry, Agha Mirza, Jada Moseley, Heba H. Mostafa, Melody Mumford, Kathleen Munoz, Arika D. Murray, Moira Nolan, Nil A. Parikh, Andrew Pekosz, Janna Pflugmacher, Janise M. Phillips, Collin Pitts, Mark C. Potter, James Quisenberry, Janelle Rear, Matthew L. Robinson, Edith Rosillo, Leslie N. Rye, MaryEllen Sherwood, Anna Simon, Jamie M. Singson, Carly Skadden, Tina H. Skelton, Charlie Smith, Mary Stech, Ryan Thomas, Matthew A. Tomaszewski, Erika A. Tyburski, Scott Vanwingerden, Evette Vlach, Ronald S. Watkins, Karriem Watson, Karen C. White, Timothy L. Killeen, Robert J. Jones, Andreas C. Cangellaris, Susan A. Martinis, Awais Vaid, Christopher B. Brooke, Joseph T. Walsh, Ahmed Elbanna, William C. Sullivan, Rebecca L. Smith, Nigel Goldenfeld, Timothy M. Fan, Paul J. Hergenrother, Martin D. Burke

    Published 2022-06-01
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