Low-coverage whole-genome sequencing of cerebrospinal-fluid-derived cell-free DNA in brain tumor patients by Anthony P.Y. Liu, Kyle S. Smith, Rahul Kumar, Giles W. Robinson, Paul A. Northcott

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Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth by Runxiang Qiu, Jun Wu, Brian Gudenas, Paul A. Northcott, Robert J. Wechsler-Reya, Qiang Lu

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Lmx1a is a master regulator of the cortical hem by Igor Y Iskusnykh, Nikolai Fattakhov, Yiran Li, Laure Bihannic, Matthew K Kirchner, Ekaterina Y Steshina, Paul A Northcott, Victor V Chizhikov

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PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis by Max J. van Essen, Elizabeth J. Apsley, Joey Riepsaame, Ruijie Xu, Paul A. Northcott, Sally A. Cowley, John Jacob, Esther B. E. Becker

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Proteomic analysis of Medulloblastoma reveals functional biology with translational potential by Samuel Rivero-Hinojosa, Ling San Lau, Mojca Stampar, Jerome Staal, Huizhen Zhang, Heather Gordish-Dressman, Paul A. Northcott, Stefan M. Pfister, Michael D. Taylor, Kristy J. Brown, Brian R. Rood

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Genetic and Epigenetic Inactivation of Kruppel-like Factor 4 in Medulloblastoma by Yukiko Nakahara, Paul A. Northcott, Meihua Li, Paul N. Kongkham, Christian Smith, Hai Yan, Sidney Croul, Young-Shin Ra, Charles Eberhart, Annie Huang, Darell Bigner, Wesia Grajkowska, Timothy Van Meter, James T. Rutka, Michael D. Taylor

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TelomereHunter – in silico estimation of telomere content and composition from cancer genomes by Lars Feuerbach, Lina Sieverling, Katharina I. Deeg, Philip Ginsbach, Barbara Hutter, Ivo Buchhalter, Paul A. Northcott, Sadaf S. Mughal, Priya Chudasama, Hanno Glimm, Claudia Scholl, Peter Lichter, Stefan Fröhling, Stefan M. Pfister, David T. W. Jones, Karsten Rippe, Benedikt Brors

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MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. by Livia Garzia, Immacolata Andolfo, Emilio Cusanelli, Natascia Marino, Giuseppe Petrosino, Daniela De Martino, Veronica Esposito, Aldo Galeone, Luigi Navas, Silvia Esposito, Sara Gargiulo, Sarah Fattet, Vittoria Donofrio, Giuseppe Cinalli, Arturo Brunetti, Luigi Del Vecchio, Paul A Northcott, Olivier Delattre, Michael D Taylor, Achille Iolascon, Massimo Zollo

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Author Correction: scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy by Jennifer Karin Ocasio, Benjamin Babcock, Daniel Malawsky, Seth J. Weir, Lipin Loo, Jeremy M. Simon, Mark J. Zylka, Duhyeong Hwang, Taylor Dismuke, Marina Sokolsky, Elias P. Rosen, Rajeev Vibhakar, Jiao Zhang, Olivier Saulnier, Maria Vladoiu, Ibrahim El-Hamamy, Lincoln D. Stein, Michael D. Taylor, Kyle S. Smith, Paul A. Northcott, Alejandro Colaneri, Kirk Wilhelmsen, Timothy R. Gershon

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Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme by Weijun Feng, Daisuke Kawauchi, Huiqin Körkel-Qu, Huan Deng, Elisabeth Serger, Laura Sieber, Jenna Ariel Lieberman, Silvia Jimeno-González, Sander Lambo, Bola S. Hanna, Yassin Harim, Malin Jansen, Anna Neuerburg, Olga Friesen, Marc Zuckermann, Vijayanad Rajendran, Jan Gronych, Olivier Ayrault, Andrey Korshunov, David T. W. Jones, Marcel Kool, Paul A. Northcott, Peter Lichter, Felipe Cortés-Ledesma, Stefan M. Pfister, Hai-Kun Liu

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Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation by Erin A Bassett, Nicholas Tokarew, Ema A Allemano, Chantal Mazerolle, Katy Morin, Alan J Mears, Brian McNeill, Randy Ringuette, Charles Campbell, Sheila Smiley, Neno T Pokrajac, Adrian M Dubuc, Vijay Ramaswamy, Paul A Northcott, Marc Remke, Philippe P Monnier, David Potter, Kim Paes, Laura L Kirkpatrick, Kenneth J Coker, Dennis S Rice, Carol Perez-Iratxeta, Michael D Taylor, Valerie A Wallace

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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma by Chen He, Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn H. Kasper, Junyuan Zhang, Xiaoyu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Yingzhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick Boop, Amar Gajjar, Jinghui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman III, Martine F. Roussel, Paul A. Northcott, Taosheng Chen, Zoran Rankovic, Gang Wu, Jason Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker

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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors by Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picard, Nan Qin, Gabriele Cancila, Qingsong Gao, Soumav Nath, Idriss Mahoungou Koumba, Marietta Wolter, François Kuonen, Maike Langini, Thomas Beez, Christopher Munoz, David Pauck, Viktoria Marquardt, Hua Yu, Judith Souphron, Mascha Korsch, Christina Mölders, Daniel Berger, Sarah Göbbels, Frauke-Dorothee Meyer, Björn Scheffler, Barak Rotblat, Sven Diederichs, Vijay Ramaswamy, Hiromishi Suzuki, Anthony Oro, Kai Stühler, Anja Stefanski, Ute Fischer, Gabriel Leprivier, Dieter Willbold, Gerhard Steger, Alexander Buell, Marcel Kool, Peter Lichter, Stefan M. Pfister, Paul A. Northcott, Michael D. Taylor, Arndt Borkhardt, Guido Reifenberger, Olivier Ayrault, Marc Remke

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Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma by Liana Nobre, Michal Zapotocky, Sara Khan, Kohei Fukuoka, Adriana Fonseca, Tara McKeown, David Sumerauer, Ales Vicha, Wieslawa A. Grajkowska, Joanna Trubicka, Kay Ka Wai Li, Ho-Keung Ng, Luca Massimi, Ji Yeoun Lee, Seung-Ki Kim, Shayna Zelcer, Alexandre Vasiljevic, Cécile Faure-Conter, Peter Hauser, Boleslaw Lach, Marie-Lise van Veelen-Vincent, Pim J. French, Erwin G. Van Meir, William A. Weiss, Nalin Gupta, Ian F. Pollack, Ronald L. Hamilton, Amulya A. Nageswara Rao, Caterina Giannini, Joshua B. Rubin, Andrew S. Moore, Lola B. Chambless, Rajeev Vibhakar, Young Shin Ra, Maura Massimino, Roger E. McLendon, Helen Wheeler, Massimo Zollo, Veronica Ferruci, Toshihiro Kumabe, Claudia C. Faria, Jaroslav Sterba, Shin Jung, Enrique López-Aguilar, Jaume Mora, Carlos G. Carlotti, James M. Olson, Sarah Leary, Jason Cain, Lenka Krskova, Josef Zamecnik, Cynthia E. Hawkins, Uri Tabori, Annie Huang, Ute Bartels, Paul A. Northcott, Michael D. Taylor, Stephen Yip, Jordan R. Hansford, Eric Bouffet, Vijay Ramaswamy

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