Cell-Type Specific Penetrating Peptides: Therapeutic Promises and Challenges von Maliha Zahid, Paul D. Robbins

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The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis von Chenjie Yang, Paul D. Robbins

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Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice. von Melanie A Ruffner, Paul D Robbins

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SIRT1 negatively regulates the mammalian target of rapamycin. von Hiyaa Singhee Ghosh, Michael McBurney, Paul D Robbins

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Exosomes released from Mycoplasma infected tumor cells activate inhibitory B cells. von Chenjie Yang, Geetha Chalasani, Yue-Harn Ng, Paul D Robbins

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Tumor-derived exosomes confer antigen-specific immunosuppression in a murine delayed-type hypersensitivity model. von Chenjie Yang, Seon-Hee Kim, Nicole R Bianco, Paul D Robbins

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Immune Senescence, Immunosenescence and Aging von Kyoo-A Lee, Rafael R. Flores, In Hwa Jang, Ashley Saathoff, Paul D. Robbins

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Cellular senescence: a key therapeutic target in aging and diseases von Lei Zhang, Louise E. Pitcher, Matthew J. Yousefzadeh, Laura J. Niedernhofer, Paul D. Robbins, Yi Zhu

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Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice. von Jonathan D Proto, Aiping Lu, Akaitz Dorronsoro, Alex Scibetta, Paul D Robbins, Laura J Niedernhofer, Johnny Huard

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Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes von Marta Garcia-Contreras, Sanket H. Shah, Alejandro Tamayo, Paul D. Robbins, Ronald B. Golberg, Armando J. Mendez, Camillo Ricordi

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Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities von Prashanta Silwal, Allison M. Nguyen-Thai, Haneef Ahamed Mohammad, Yanshan Wang, Paul D. Robbins, Joon Y. Lee, Nam V. Vo

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Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease von Zhiyin Xun, Sulay Rivera-Sánchez, Sylvette Ayala-Peña, James Lim, Helen Budworth, Erin M. Skoda, Paul D. Robbins, Laura J. Niedernhofer, Peter Wipf, Cynthia T. McMurray

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Systemic delivery of NEMO binding domain/IKKγ inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology von Daniel P. Reay, Michele Yang, Jon F. Watchko, Molly Daood, Terrence L. O'Day, Khaleel K. Rehman, Denis C. Guttridge, Paul D. Robbins, Paula R. Clemens

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Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells von Lei Liu, Xianlin Yue, Zewei Sun, William S. Hambright, Jianming Wei, Ying Li, Polina Matre, Yan Cui, Zhihui Wang, George Rodney, Johnny Huard, Paul D. Robbins, Xiaodong Mu

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Possible novel therapy for malignant gliomas with secretable trimeric TRAIL. von Moonsup Jeong, Yong-Sam Kwon, Soon-Hye Park, Chae-Young Kim, Sin-Soo Jeun, Kang-Won Song, Yong Ko, Paul D Robbins, Timothy R Billiar, Byong-Moon Kim, Dai-Wu Seol

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Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging von Aditi U. Gurkar, Andria R. Robinson, Yuxiang Cui, Xuesen Li, Shailaja K. Allani, Amanda Webster, Mariya Muravia, Mohammad Fallahi, Herbert Weissbach, Paul D. Robbins, Yinsheng Wang, Eric E. Kelley, Claudette M. St. Croix, Laura J. Niedernhofer, Matthew S. Gill

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Aging and chronic inflammation: highlights from a multidisciplinary workshop von Danay Saavedra, Ana Laura Añé-Kourí, Nir Barzilai, Calogero Caruso, Kyung-Hyun Cho, Luigi Fontana, Claudio Franceschi, Daniela Frasca, Nuris Ledón, Laura J. Niedernhofer, Karla Pereira, Paul D. Robbins, Alexa Silva, Gisela M. Suarez, Wim Vanden Berghe, Thomas von Zglinicki, Graham Pawelec, Agustín Lage

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Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation. von Jing Zhao, Lei Zhang, Xiaodong Mu, Christelle Doebelin, William Nguyen, Callen Wallace, Daniel P Reay, Sara J McGowan, Lana Corbo, Paula R Clemens, Gabriela Mustata Wilson, Simon C Watkins, Laura A Solt, Michael D Cameron, Johnny Huard, Laura J Niedernhofer, Theodore M Kamenecka, Paul D Robbins

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Identification of HSP90 inhibitors as a novel class of senolytics von Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J. McGowan, Yi Zhu, Robert W. Brooks, Diego Grassi, Siobhan Q. Gregg, Jennifer L. Stripay, Akaitz Dorronsoro, Lana Corbo, Priscilla Tang, Christina Bukata, Nadja Ring, Mauro Giacca, Xuesen Li, Tamara Tchkonia, James L. Kirkland, Laura J. Niedernhofer, Paul D. Robbins

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A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues von Dominik Saul, Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, Nathan K. LeBrasseur, Robert J. Pignolo, Paul D. Robbins, Laura J. Niedernhofer, Yuji Ikeno, Diana Jurk, João F. Passos, LaTonya J. Hickson, Ailing Xue, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Joshua N. Farr, Sundeep Khosla

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