The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis ανά Chenjie Yang, Paul D. Robbins

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Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice. ανά Melanie A Ruffner, Paul D Robbins

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SIRT1 negatively regulates the mammalian target of rapamycin. ανά Hiyaa Singhee Ghosh, Michael McBurney, Paul D Robbins

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Exosomes released from Mycoplasma infected tumor cells activate inhibitory B cells. ανά Chenjie Yang, Geetha Chalasani, Yue-Harn Ng, Paul D Robbins

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Tumor-derived exosomes confer antigen-specific immunosuppression in a murine delayed-type hypersensitivity model. ανά Chenjie Yang, Seon-Hee Kim, Nicole R Bianco, Paul D Robbins

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Immune Senescence, Immunosenescence and Aging ανά Kyoo-A Lee, Rafael R. Flores, In Hwa Jang, Ashley Saathoff, Paul D. Robbins

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Cellular senescence: a key therapeutic target in aging and diseases ανά Lei Zhang, Louise E. Pitcher, Matthew J. Yousefzadeh, Laura J. Niedernhofer, Paul D. Robbins, Yi Zhu

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Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice. ανά Jonathan D Proto, Aiping Lu, Akaitz Dorronsoro, Alex Scibetta, Paul D Robbins, Laura J Niedernhofer, Johnny Huard

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Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities ανά Prashanta Silwal, Allison M. Nguyen-Thai, Haneef Ahamed Mohammad, Yanshan Wang, Paul D. Robbins, Joon Y. Lee, Nam V. Vo

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Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells ανά Lei Liu, Xianlin Yue, Zewei Sun, William S. Hambright, Jianming Wei, Ying Li, Polina Matre, Yan Cui, Zhihui Wang, George Rodney, Johnny Huard, Paul D. Robbins, Xiaodong Mu

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Possible novel therapy for malignant gliomas with secretable trimeric TRAIL. ανά Moonsup Jeong, Yong-Sam Kwon, Soon-Hye Park, Chae-Young Kim, Sin-Soo Jeun, Kang-Won Song, Yong Ko, Paul D Robbins, Timothy R Billiar, Byong-Moon Kim, Dai-Wu Seol

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Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging ανά Aditi U. Gurkar, Andria R. Robinson, Yuxiang Cui, Xuesen Li, Shailaja K. Allani, Amanda Webster, Mariya Muravia, Mohammad Fallahi, Herbert Weissbach, Paul D. Robbins, Yinsheng Wang, Eric E. Kelley, Claudette M. St. Croix, Laura J. Niedernhofer, Matthew S. Gill

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Aging and chronic inflammation: highlights from a multidisciplinary workshop ανά Danay Saavedra, Ana Laura Añé-Kourí, Nir Barzilai, Calogero Caruso, Kyung-Hyun Cho, Luigi Fontana, Claudio Franceschi, Daniela Frasca, Nuris Ledón, Laura J. Niedernhofer, Karla Pereira, Paul D. Robbins, Alexa Silva, Gisela M. Suarez, Wim Vanden Berghe, Thomas von Zglinicki, Graham Pawelec, Agustín Lage

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Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation. ανά Jing Zhao, Lei Zhang, Xiaodong Mu, Christelle Doebelin, William Nguyen, Callen Wallace, Daniel P Reay, Sara J McGowan, Lana Corbo, Paula R Clemens, Gabriela Mustata Wilson, Simon C Watkins, Laura A Solt, Michael D Cameron, Johnny Huard, Laura J Niedernhofer, Theodore M Kamenecka, Paul D Robbins

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A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues ανά Dominik Saul, Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, Nathan K. LeBrasseur, Robert J. Pignolo, Paul D. Robbins, Laura J. Niedernhofer, Yuji Ikeno, Diana Jurk, João F. Passos, LaTonya J. Hickson, Ailing Xue, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Joshua N. Farr, Sundeep Khosla

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Local senolysis in aged mice only partially replicates the benefits of systemic senolysis ανά Joshua N. Farr, Dominik Saul, Madison L. Doolittle, Japneet Kaur, Jennifer L. Rowsey, Stephanie J. Vos, Mitchell N. Froemming, Anthony B. Lagnado, Yi Zhu, Megan Weivoda, Yuji Ikeno, Robert J. Pignolo, Laura J. Niedernhofer, Paul D. Robbins, Diana Jurk, João F. Passos, Nathan K. LeBrasseur, Tamara Tchkonia, James L. Kirkland, David G. Monroe, Sundeep Khosla

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Fisetin is a senotherapeutic that extends health and lifespanResearch in Context ανά Matthew J. Yousefzadeh, Yi Zhu, Sara J. McGowan, Luise Angelini, Heike Fuhrmann-Stroissnigg, Ming Xu, Yuan Yuan Ling, Kendra I. Melos, Tamar Pirtskhalava, Christina L. Inman, Collin McGuckian, Erin A. Wade, Jonathon I. Kato, Diego Grassi, Mark Wentworth, Christin E. Burd, Edgar A. Arriaga, Warren L. Ladiges, Tamara Tchkonia, James L. Kirkland, Paul D. Robbins, Laura J. Niedernhofer

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