Hyaluronic acid is associated with organ dysfunction in acute respiratory distress syndrome ανά Anthony J. Esposito, Pavan K. Bhatraju, Renee D. Stapleton, Mark M. Wurfel, Carmen Mikacenic

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Machine learning-based derivation and external validation of a tool to predict death and development of organ failure in hospitalized patients with COVID-19 ανά Yixi Xu, Anusua Trivedi, Nicholas Becker, Marian Blazes, Juan Lavista Ferres, Aaron Lee, W. Conrad Liles, Pavan K. Bhatraju

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Subphenotypes in acute kidney injury: a narrative review ανά Suvi T. Vaara, Pavan K. Bhatraju, Natalja L. Stanski, Blaithin A. McMahon, Kathleen Liu, Michael Joannidis, Sean M. Bagshaw

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Biological subphenotypes in patients hospitalized with suspected infection in Thailand: a secondary analysis of a prospective observational studyResearch in context ανά Prapassorn Poolchanuan, Taylor D. Coston, Viriya Hantrakun, Parinya Chamnan, Gumphol Wongsuvan, Pavan K. Bhatraju, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West, Shelton W. Wright

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Assessment of kidney proximal tubular secretion in critical illness ανά Pavan K. Bhatraju, Xin-Ya Chai, Neha A. Sathe, John Ruzinski, Edward D. Siew, Jonathan Himmelfarb, Andrew N. Hoofnagle, Mark M. Wurfel, Bryan R. Kestenbaum

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Effective deep learning approaches for predicting COVID-19 outcomes from chest computed tomography volumes ανά Anthony Ortiz, Anusua Trivedi, Jocelyn Desbiens, Marian Blazes, Caleb Robinson, Sunil Gupta, Rahul Dodhia, Pavan K. Bhatraju, W. Conrad Liles, Aaron Lee, Juan M. Lavista Ferres

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Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype ανά Pavan K. Bhatraju, Cassianne Robinson-Cohen, Carmen Mikacenic, Susanna Harju-Baker, Victoria Dmyterko, Natalie S. J. Slivinski, W. Conrad Liles, Jonathan Himmelfarb, Susan R. Heckbert, Mark M. Wurfel

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Deep learning models for COVID-19 chest x-ray classification: Preventing shortcut learning using feature disentanglement ανά Anusua Trivedi, Caleb Robinson, Marian Blazes, Anthony Ortiz, Jocelyn Desbiens, Sunil Gupta, Rahul Dodhia, Pavan K. Bhatraju, W. Conrad Liles, Jayashree Kalpathy-Cramer, Aaron Y. Lee, Juan M. Lavista Ferres

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Mediators of monocyte chemotaxis and matrix remodeling are associated with mortality and pulmonary fibroproliferation in patients with severe COVID-19. ανά Sarah E Holton, Mallorie Mitchem, Hamid Chalian, Sudhakar Pipavath, Eric D Morrell, Pavan K Bhatraju, Jessica A Hamerman, Cate Speake, Uma Malhotra, Mark M Wurfel, Steven E Ziegler, Carmen Mikacenic

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Deep learning models for COVID-19 chest x-ray classification: Preventing shortcut learning using feature disentanglement. ανά Anusua Trivedi, Caleb Robinson, Marian Blazes, Anthony Ortiz, Jocelyn Desbiens, Sunil Gupta, Rahul Dodhia, Pavan K Bhatraju, W Conrad Liles, Jayashree Kalpathy-Cramer, Aaron Y Lee, Juan M Lavista Ferres

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Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approach ανά Neha A. Sathe, Su Xian, F. Linzee Mabrey, David R. Crosslin, Sean D. Mooney, Eric D. Morrell, Kevin Lybarger, Meliha Yetisgen, Gail P. Jarvik, Pavan K. Bhatraju, Mark M. Wurfel

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Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service ανά Sarah M. Baker, Doug J. Leedy, Jesse Abbott Klafter, Yilin Zhang, Kayla M. Secrest, Tristan R. Osborn, Richard K. Cheng, Seth D. Judson, Susan E. Merel, Carmen Mikacenic, Pavan K. Bhatraju, W. Conrad Liles

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Mitochondrial N-formyl methionine peptides contribute to exaggerated neutrophil activation in patients with COVID-19 ανά Runa Kuley, Bhargavi Duvvuri, Jeffrey J. Wallin, Nam Bui, Mary Vic Adona, Nicholas G. O’Connor, Sharon K. Sahi, Ian B. Stanaway, Mark M. Wurfel, Eric D. Morrell, W. Conrad Liles, Pavan K. Bhatraju, Christian Lood

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Presence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus-2 on Admission Is Associated With Decreased Mortality in COVID-19 Critical Illness ανά F. Linzee Mabrey, MD, Leila R. Zelnick, PhD, Eric D. Morrell, MD, Nicholas G. O’Connor, BS, Andrew Hart, BA, Mark M. Wurfel, MD, PhD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc

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Kidney Outcomes and Trajectories of Tubular Injury and Function in Critically Ill Patients With and Without COVID-19 ανά Michael L. Granda, MD, MS, Frances Tian, MD, Leila R. Zelnick, PhD, Pavan K. Bhatraju, MD, MSc, Julia Hallowell, BS, Mark M. Wurfel, MD, PhD, Andrew Hoofnagle, MD, PhD, Eric Morrell, MD, Bryan Kestenbaum, MD, MS

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Inflammation, endothelial injury, and the acute respiratory distress syndrome after out-of-hospital cardiac arrest ανά Sarah C. Katsandres, Jane Hall, Kyle Danielson, Sana Sakr, Sarah G. Dean, David J. Carlbom, Mark M. Wurfel, Pavan K. Bhatraju, Joseph A. Hippensteel, Eric P. Schmidt, Kaori Oshima, Catherine R. Counts, Michael R. Sayre, Daniel J. Henning, Nicholas J. Johnson

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Plasma Interleukin-6 Predicts Clinical Decline After Completion of Dexamethasone Therapy in Severe COVID-19 ανά F. Linzee Mabrey, MD, Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Leila R. Zelnick, PhD, Neha A. Sathe, MD, Nicholas G. O’Connor, BS, Carmen Mikacenic, MD, Thomas R. Martin, MD, W. Conrad Liles, MD, PhD, Mark M. Wurfel, MD, PhD

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Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes ανά Pavan K. Bhatraju, Max Cohen, Ryan J. Nagao, Eric D. Morrell, Susanna Kosamo, Xin-Ya Chai, Robin Nance, Victoria Dmyterko, Joseph Delaney, Jason D. Christie, Kathleen D. Liu, Carmen Mikacenic, Sina A. Gharib, W. Conrad Liles, Ying Zheng, David C. Christiani, Jonathan Himmelfarb, Mark M. Wurfel

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Biomarker Signatures of Severe Acute Kidney Injury in a Critically Ill Cohort of COVID-19 and Non-COVID-19 Acute Respiratory Illness ανά Neha A. Sathe, MD, MSc, Ana Mostaghim, MD, Elizabeth Barnes, BS, Nicholas G. O’Connor, BS, Sharon K. Sahi, MS, Sana S. Sakr, PhD, Jana M. Zahlan, BS, Craig H. Smith, MD, Michael Fitzpatrick, BS, Eric D. Morrell, MD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc

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Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations ανά Louisa Helms, Silvia Marchiano, Ian B. Stanaway, Tien-Ying Hsiang, Benjamin A. Juliar, Shally Saini, Yan Ting Zhao, Akshita Khanna, Rajasree Menon, Fadhl Alakwaa, Carmen Mikacenic, Eric D. Morrell, Mark M. Wurfel, Matthias Kretzler, Jennifer L. Harder, Charles E. Murry, Jonathan Himmelfarb, Hannele Ruohola-Baker, Pavan K. Bhatraju, Michael Gale Jr., Benjamin S. Freedman

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