Vejle Diabetes Biobank – a resource for studies of the etiologies of diabetes and its comorbidities ‌ Petersen ERB, Nielsen AA, Christensen H, Hansen T, Pedersen O, Christensen CK, Brandslund I

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The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project: rationale and planned nationwide studies of genetic predictors, physical exercise, and individualized pha... ‌ Steffensen C, Thomsen RW, Vaag A, Beck-Nielsen H, Christiansen JS, Hansen T, Pedersen O, Rungby J

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Evidence that the LARS2 gene represents a novel type 2 diabetes mellitus gene ‌ Reiling, E, Dekker, J, Hansen, T, Weedon, M, Nijpels, G, Hitman, G, Walker, M, McCarthy, M, Pedersen, O, Heine, R, Maassen, J, t Hart, L

Cohort description: The Danish study of Functional Disorders ‌ Dantoft TM, Ebstrup JF, Linneberg A, Skovbjerg S, Madsen AL, Mehlsen J, Brinth L, Eplov LF, Carstensen TW, Schroder A, Fink PK, Mortensen EL, Hansen T, Pedersen O, Jørgensen T

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Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release. ‌ Hansen, S, Gjesing, A, Rasmussen, S, Glümer, C, Urhammer, SA, Andersen, G, Rose, C, Drivsholm, T, Torekov, S, Jensen, D, Ekstrøm, C, Borch-Johnsen, K, Jørgensen, T, McCarthy, M, Hansen, T, Pedersen, O

Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers ‌ Schnurr, TM, Jørsboe, E, Chadt, A, Dahl-Petersen, IK, Kristensen, JM, Wojtaszewski, JFP, Springer, C, Bjerregaard, P, Brage, S, Pedersen, O, Moltke, I, Grarup, N, Al-Hasani, H, Albrechtsen, A, Jørgensen, ME, Hansen, T

Voices: insulin and beyond ‌ Roth, J, Ashcroft, FM, Wollheim, CB, Kieffer, TJ, Cherrington, AD, Bergman, RN, Taylor, R, Najjar, SM, Pedersen, O, Ellingsgaard, H, Holst, JJ, Nauck, MA, Kadowaki, T, Czech, MP, Corvera, S, Saltiel, AR, Corkey, BE, Atkinson, MA

A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity. ‌ Frayling, T, Lindgren, C, Chevre, J, Menzel, S, Wishart, M, Benmezroua, Y, Brown, A, Evans, J, Rao, P, Dina, C, Lecoeur, C, Kanninen, T, Almgren, P, Bulman, M, Wang, Y, Mills, J, Wright-Pascoe, R, Mahtani, M, Prisco, F, Costa, A, Cognet, I, Hansen, T, Pedersen, O, Ellard, S, Tuomi, T

A role for coding functional variants in HNF4A in type 2 diabetes susceptibility ‌ Jafar-Mohammadi, B, Groves, C, Gjesing, A, Herrera, B, Winckler, W, Stringham, H, Morris, A, Lauritzen, T, Doney, A, Morris, A, Weedon, M, Swift, A, Kuusisto, J, Laakso, M, Altshuler, D, Hattersley, A, Collins, F, Boehnke, M, Hansen, T, Pedersen, O, Palmer, C, Frayling, T, Gloyn, A, McCarthy, M

A role for coding functional variants in HNF4A in type 2 diabetes susceptibility. ‌ Jafar-Mohammadi, B, Groves, C, Gjesing, A, Herrera, B, Winckler, W, Stringham, H, Morris, A, Lauritzen, T, Doney, A, Morris, A, Weedon, M, Swift, A, Kuusisto, J, Laakso, M, Altshuler, D, Hattersley, A, Collins, F, Boehnke, M, Hansen, T, Pedersen, O, Palmer, C, Frayling, T, Gloyn, A, McCarthy, M

A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes ‌ Thanabalasingham, G, Shah, N, Vaxillaire, M, Hansen, T, Tuomi, T, Gašperíková, D, Szopa, M, Tjora, E, James, T, Kokko, P, Loiseleur, F, Andersson, E, Gaget, S, Isomaa, B, Nowak, N, Raeder, H, Stanik, J, Njolstad, P, Malecki, M, Klimes, I, Groop, L, Pedersen, O, Froguel, P, McCarthy, M, Gloyn, A

A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes. ‌ Thanabalasingham, G, Shah, N, Vaxillaire, M, Hansen, T, Tuomi, T, Gašperíková, D, Szopa, M, Tjora, E, James, T, Kokko, P, Loiseleur, F, Andersson, E, Gaget, S, Isomaa, B, Nowak, N, Raeder, H, Stanik, J, Njolstad, P, Malecki, M, Klimes, I, Groop, L, Pedersen, O, Froguel, P, McCarthy, M, Gloyn, A

Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study ‌ Sharma, S, Dong, Q, Haid, M, Adam, J, Bizzotto, R, Fernandez-Tajes, JJ, Jones, AG, Tura, A, Artati, A, Prehn, C, Kastenmüller, G, Koivula, RW, Franks, PW, Walker, M, Forgie, IM, Giordano, G, Pavo, I, Ruetten, H, Dermitzakis, M, McCarthy, MI, Pedersen, O, Schwenk, JM, Tsirigos, KD, De Masi, F

Genetic association analysis of LARS2 with type 2 diabetes. ‌ Reiling, E, Jafar-Mohammadi, B, van 't Riet, E, Weedon, M, van Vliet-Ostaptchouk, J, Hansen, T, Saxena, R, van Haeften, T, Arp, P, Das, S, Nijpels, G, Groenewoud, M, van Hove, E, Uitterlinden, A, Smit, J, Morris, A, Doney, A, Palmer, C, Guiducci, C, Hattersley, A, Frayling, T, Pedersen, O, Slagboom, P, Altshuler, D, Groop, L

Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ‌ Andersen, MK, Skotte, L, Jørsboe, E, Polito, R, Stæger, FF, Aldiss, P, Hanghøj, K, Waples, RK, Santander, CG, Grarup, N, Dahl-Petersen, IK, Diaz, LJ, Overvad, M, Senftleber, NK, Søborg, B, Larsen, CVL, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, ME, Færgeman, NJ, Koch, A, Moritz, T, Gillum, MP, Moltke, I, Hansen, T, Albrechtsen, A

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria ‌ Ahluwalia, T, Schulz, C, Waage, J, Skaaby, T, Sandholm, N, Van Zuydam, N, Charmet, R, Bork-Jensen, J, Almgren, P, Thuesen, B, Bedin, M, Brandslund, I, Christensen, C, Linneberg, A, Ahlqvist, E, Groop, P, Hadjadj, S, Tregouet, D, Jørgensen, M, Grarup, N, Pedersen, O, Simons, M, Groop, L, Orho-Melander, M, McCarthy, M, Melander, O, Rossing, P, Kilpeläinen, T, Hansen, T

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consort... ‌ Koivula, R, Franks, P, Heggie, A, Walker, M, Barnett, A, Pearson, E, Cederberg, H, Siloaho, M, Laakso, M, Hansen, T, Vestergaard, H, Hansen, T, Pedersen, O, Koopman, A, Rutters, F, Heymans, M, Dekker, J, Rauh, S, Ridderstråle, M, Gupta, R, Herrgård, S, Brunak, S, Perry, M, McDonald, T, Teare, H, Thorand, B, Bell, J, Frost, G, Jablonka, B, Ruetten, H, Mari, A, Hattersley, A, Koivisto, V

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study ‌ Langenberg, C, Sharp, S, Franks, P, Scott, R, Deloukas, P, Forouhi, N, Froguel, P, Groop, L, Hansen, T, Palla, L, Pedersen, O, Schulze, M, Tormo, M, Wheeler, E, Agnoli, C, Arriola, L, Barricarte, A, Boeing, H, Clarke, G, Clavel-Chapelon, F, Duell, E, Fagherazzi, G, Kaaks, R, Kerrison, N, Key, T, Khaw, K, Kröger, J, Lajous, M, Morris, A, Navarro, C, Nilsson, P, Overvad, K, Palli, D, Panico, S, Quirós, JR, Rolandsson, O, Sacerdote, C, Sánchez, M, Slimani, N, Spijkerman, A, Tumino, R, Van Der A, D, Van Der Schouw, Y, Barroso, I, McCarthy, M, Riboli, E, Wareham, N

A genome-wide association study of IVGTT-based measures of first phase insulin secretion refines the underlying physiology of Type 2 Diabetes variants. ‌ Wood, A, Jonsson, A, Jackson, A, Wang, N, van Leewen, N, Palmer, N, Kobes, S, Deelen, J, Boquete-Vilarino, L, Paananen, J, Stančáková, A, Boomsma, D, de Geus, E, Eekhoff, E, Fritsche, A, Kramer, M, Nijpels, G, Simonis-Bik, A, van Haeften, T, Mahajan, A, Boehnke, M, Bergman, R, Tuomilehto, J, Collins, F, Mohlke, K, Banasik, K, Groves, C, McCarthy, M, Pearson, E, Natali, A, Mari, A, Buchanan, T, Taylor, K, Xiang, A, Gjesing, A, Grarup, N, Eiberg, H, Pedersen, O, Chen, Y, Laakso, M, Norris, J, Smith, U, Wagenknecht, L, Baier, L, Bowden, D, Hansen, T, Walker, M, Watanabe, R, 't Hart, L, Hanson, R, Frayling, T

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT... ‌ Koivula, RW, Forgie, IM, Kurbasic, A, Viñuela, A, Heggie, A, Giordano, GN, Hansen, TH, Hudson, M, Koopman, ADM, Rutters, F, Siloaho, M, Allin, KH, Brage, S, Brorsson, CA, Dawed, AY, De Masi, F, Groves, CJ, Kokkola, T, Mahajan, A, Perry, MH, Rauh, SP, Ridderstråle, M, Teare, HJA, Thomas, EL, Tura, A, Vestergaard, H, White, T, Adamski, J, Bell, JD, Beulens, JW, Brunak, S, Dermitzakis, ET, Froguel, P, Frost, G, Gupta, R, Hansen, T, Hattersley, A, Jablonka, B, Kaye, J, Laakso, M, McDonald, TJ, Pedersen, O, Schwenk, JM, Pavo, I, Mari, A, McCarthy, MI, Ruetten, H, Walker, M, Pearson, E, Franks, PW, Imi Direct Consortium