Using Zebrafish as a Disease Model to Study Fibrotic Disease by Xixin Wang, Daniëlle Copmans, Peter A. M. de Witte

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An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies by Parthena Martin, Thadd Reeder, Jo Sourbron, Peter A. M. de Witte, Arnold R. Gammaitoni, Bradley S. Galer

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Comparative Antiseizure Analysis of Diverse Natural Coumarin Derivatives in Zebrafish by Ewelina Kozioł, Krzysztof Jóźwiak, Barbara Budzyńska, Peter A. M. de Witte, Daniëlle Copmans, Krystyna Skalicka-Woźniak

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Evaluation of 14 organic solvents and carriers for screening applications in zebrafish embryos and larvae. by Jan Maes, Lien Verlooy, Olivia E Buenafe, Peter A M de Witte, Camila V Esguerra, Alexander D Crawford

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Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis by Marlly Guarin, Annelii Ny, Noémie De Croze, Jan Maes, Marc Léonard, Pieter Annaert, Peter A. M. de Witte

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Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor by Marie Pardon, Pieter Claes, Sarah Druwé, Murielle Martini, Aleksandra Siekierska, Christel Menet, Peter A. M. de Witte, Daniëlle Copmans

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Insights from zebrafish and mouse models on the activity and safety of ar-turmerone as a potential drug candidate for the treatment of epilepsy. by Adriana Monserrath Orellana-Paucar, Tatiana Afrikanova, Joice Thomas, Yelaman K Aibuldinov, Wim Dehaen, Peter A M de Witte, Camila V Esguerra

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Zebrafish Bioassay-guided Microfractionation for the Rapid in vivo Identification of Pharmacologically Active Natural Products by Soura Challal, Nadine Bohni, Olivia E. Buenafe, Camila V. Esguerra, Peter A. M. de Witte, Jean-Luc Wolfender, Alexander D. Crawford

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Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine. by Yifan Zhang, Angéla Kecskés, Daniëlle Copmans, Mélanie Langlois, Alexander D Crawford, Berten Ceulemans, Lieven Lagae, Peter A M de Witte, Camila V Esguerra

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Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish by Yifan Zhang, Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Jubi John, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter A. M. de Witte, Rafal M. Kaminski

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Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants. by Alexander D Crawford, Sandra Liekens, Appolinary R Kamuhabwa, Jan Maes, Sebastian Munck, Roger Busson, Jef Rozenski, Camila V Esguerra, Peter A M de Witte

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Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites... by María Lorena Cordero-Maldonado, Dany Siverio-Mota, Liliana Vicet-Muro, Isabel María Wilches-Arizábala, Camila V Esguerra, Peter A M de Witte, Alexander D Crawford

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Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B by Daniëlle Copmans, Sara Kildgaard, Silas A. Rasmussen, Monika Ślęzak, Nina Dirkx, Michèle Partoens, Camila V. Esguerra, Alexander D. Crawford, Thomas O. Larsen, Peter A. M. de Witte

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A phenotypic screen in zebrafish identifies a novel small-molecule inducer of ectopic tail formation suggestive of alterations in non-canonical Wnt/PCP signaling. by Evelien Gebruers, María Lorena Cordero-Maldonado, Alexander I Gray, Carol Clements, Alan L Harvey, Ruangelie Edrada-Ebel, Peter A M de Witte, Alexander D Crawford, Camila V Esguerra

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Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish by Lise Heylen, Duc-Hung Pham, Ann-Sofie De Meulemeester, Éric Samarut, Éric Samarut, Adrianna Skiba, Daniëlle Copmans, Youcef Kazwiny, Pieter Vanden Berghe, Peter A. M. de Witte, Aleksandra Siekierska

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From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin by Daniëlle Copmans, Sara Kildgaard, Emma Roux, Michèle Partoens, Gert Steurs, Xinhui Wang, Wim M. De Borggraeve, Camila V. Esguerra, Alexander D. Crawford, Thomas O. Larsen, Peter A. M. de Witte

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mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis by Chloë Scheldeman, James D. Mills, Aleksandra Siekierska, Ines Serra, Daniëlle Copmans, Anand M. Iyer, Benjamin J. Whalley, Jan Maes, Anna C. Jansen, Lieven Lagae, Eleonora Aronica, Peter A.M. de Witte

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Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery by Yifan Zhang, Lise Heylen, Michèle Partoens, James D. Mills, James D. Mills, James D. Mills, Rafal M. Kaminski, Rafal M. Kaminski, Patrice Godard, Michel Gillard, Peter A. M. de Witte, Aleksandra Siekierska

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Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities by Ann-Sofie De Meulemeester, Lise Heylen, Aleksandra Siekierska, James D. Mills, James D. Mills, James D. Mills, Alessia Romagnolo, Nicole N. Van Der Wel, Eleonora Aronica, Eleonora Aronica, Peter A. M. de Witte

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Integration of Microfractionation, qNMR and zebrafish screening for the in vivo bioassay-guided isolation and quantitative bioactivity analysis of natural products. by Nadine Bohni, María Lorena Cordero-Maldonado, Jan Maes, Dany Siverio-Mota, Laurence Marcourt, Sebastian Munck, Appolinary R Kamuhabwa, Mainen J Moshi, Camila V Esguerra, Peter A M de Witte, Alexander D Crawford, Jean-Luc Wolfender

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