Entropy and Variability: A Second Opinion by Deep Learning by Daniel T. Rademaker, Li C. Xue, Peter A. C. ‘t Hoen, Gert Vriend

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Generic information can retrieve known biological associations: implications for biomedical knowledge discovery. by Herman H H B M van Haagen, Peter A C 't Hoen, Barend Mons, Erik A Schultes

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Block or degrade? Balancing on- and off-target effects of antisense strategies against transcripts with expanded triplet repeats in DM1 by Najoua El Boujnouni, M. Leontien van der Bent, Marieke Willemse, Peter A.C. ’t Hoen, Roland Brock, Derick G. Wansink

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Network-based integrative multi-omics approach reveals biosignatures specific to COVID-19 disease phases by Francis E. Agamah, Thomas H. A. Ederveen, Michelle Skelton, Darren P. Martin, Emile R. Chimusa, Peter A. C. ’t Hoen

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Ribosome profiling uncovers selective mRNA translation associated with eIF2 phosphorylation in erythroid progenitors. by Nahuel A Paolini, Kat S Moore, Franca M di Summa, Ivo F A C Fokkema, Peter A C 't Hoen, Marieke von Lindern

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Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression by Daphne Wijnbergen, Mridul Johari, Ozan Ozisik, Peter A.C. ‘t Hoen, Friederike Ehrhart, Anaïs Baudot, Chris T. Evelo, Bjarne Udd, Marco Roos, Eleni Mina

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PANDORA v2.0: Benchmarking peptide-MHC II models and software improvements by Farzaneh M. Parizi, Farzaneh M. Parizi, Dario F. Marzella, Gayatri Ramakrishnan, Peter A. C. ‘t Hoen, Mohammad Hossein Karimi-Jafari, Li C. Xue

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Quantitative analysis of myofiber type composition in human and mouse skeletal muscles by Tooba Abbassi-Daloii, Salma el Abdellaoui, Hermien E. Kan, Erik van den Akker, Peter A.C. ’t Hoen, Vered Raz, Lenard M. Voortman

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Clinical improvement of DM1 patients reflected by reversal of disease-induced gene expression in blood by Remco T. P. van Cruchten, Daniël van As, Jeffrey C. Glennon, Baziel G. M. van Engelen, Peter A. C. ‘t Hoen, the OPTIMISTIC consortium, the ReCognitION consortium

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Drug repurposing for rare: progress and opportunities for the rare disease community by Anneliene Hechtelt Jonker, Anneliene Hechtelt Jonker, Daniel O’Connor, Daniel O’Connor, Maria Cavaller-Bellaubi, Maria Cavaller-Bellaubi, Christine Fetro, Christine Fetro, Maria Gogou, Maria Gogou, Peter A. C. ’T Hoen, Peter A. C. ’T Hoen, Martin de Kort, Martin de Kort, Heather Stone, Heather Stone, Nivedita Valentine, Nivedita Valentine, Anna Maria Gerdina Pasmooij, Anna Maria Gerdina Pasmooij

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PANDORA: A Fast, Anchor-Restrained Modelling Protocol for Peptide: MHC Complexes by Dario F. Marzella, Farzaneh M. Parizi, Derek van Tilborg, Derek van Tilborg, Nicolas Renaud, Daan Sybrandi, Rafaella Buzatu, Daniel T. Rademaker, Peter A. C. ‘t Hoen, Li C. Xue

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Quantifying the deformability of malaria-infected red blood cells using deep learning trained on synthetic cells by Daniel T. Rademaker, Joshua J. Koopmans, Gwendolyn M.S.M. Thyen, Aigars Piruska, Wilhelm T.S. Huck, Gert Vriend, Peter A.C. ‘t Hoen, Taco W.A. Kooij, Martijn A. Huynen, Nicholas I. Proellochs

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SUsPECT: a pipeline for variant effect prediction based on custom long-read transcriptomes for improved clinical variant annotation by Renee Salz, Nuno Saraiva-Agostinho, Emil Vorsteveld, Caspar I. van der Made, Simone Kersten, Merel Stemerdink, Jamie Allen, Pieter-Jan Volders, Sarah E. Hunt, Alexander Hoischen, Peter A.C. ’t Hoen

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Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies by Anna Niehues, Daniele Bizzarri, Marcel J.T. Reinders, P. Eline Slagboom, Alain J. van Gool, Erik B. van den Akker, BBMRI-NL BIOS consortium, BBMRI-NL Metabolomics consortium, Peter A.C. ’t Hoen

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Ten quick tips for building FAIR workflows by Casper de Visser, Lennart F. Johansson, Purva Kulkarni, Hailiang Mei, Pieter Neerincx, K. Joeri van der Velde, Péter Horvatovich, Alain J. van Gool, Morris A. Swertz, Peter A. C. ‘t Hoen, Anna Niehues

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Ten quick tips for building FAIR workflows. by Casper de Visser, Lennart F Johansson, Purva Kulkarni, Hailiang Mei, Pieter Neerincx, K Joeri van der Velde, Péter Horvatovich, Alain J van Gool, Morris A Swertz, Peter A C 't Hoen, Anna Niehues

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Drug repurposing in Rett and Rett-like syndromes: a promising yet underrated opportunity? by Claudia Fuchs, Peter A. C. ‘t Hoen, Annelieke R. Müller, Annelieke R. Müller, Annelieke R. Müller, Friederike Ehrhart, Clara D. M. Van Karnebeek, Clara D. M. Van Karnebeek, Clara D. M. Van Karnebeek

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Comprehensive gene-expression survey identifies wif1 as a modulator of cardiomyocyte differentiation. by Henk P J Buermans, Bram van Wijk, Margriet A Hulsker, Niels C H Smit, Johan T den Dunnen, Gertjan B van Ommen, Antoon F Moorman, Maurice J van den Hoff, Peter A C 't Hoen

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Multi-omic profiling of pathogen-stimulated primary immune cells by Renee Salz, Emil E. Vorsteveld, Caspar I. van der Made, Simone Kersten, Merel Stemerdink, Tabea V. Riepe, Tsung-han Hsieh, Musa Mhlanga, Mihai G. Netea, Pieter-Jan Volders, Alexander Hoischen, Peter A.C. ’t Hoen

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Computational approaches for network-based integrative multi-omics analysis by Francis E. Agamah, Francis E. Agamah, Jumamurat R. Bayjanov, Anna Niehues, Kelechi F. Njoku, Michelle Skelton, Gaston K. Mazandu, Gaston K. Mazandu, Gaston K. Mazandu, Thomas H. A. Ederveen, Nicola Mulder, Emile R. Chimusa, Peter A. C. 't Hoen

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