Cytoplasmic chromatin fragments—from mechanisms to therapeutic potential by Karl N Miller, Nirmalya Dasgupta, Tianhui Liu, Peter D Adams, Maria Grazia Vizioli

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Placing the HIRA Histone Chaperone Complex in the Chromatin Landscape by Nikolay A. Pchelintsev, Tony McBryan, Taranjit Singh Rai, John van Tuyn, Dominique Ray-Gallet, Geneviève Almouzni, Peter D. Adams

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Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila by Maria Clara Guida, Ryan Tyge Birse, Alessandra Dall’Agnese, Paula Coutinho Toto, Soda Balla Diop, Antonello Mai, Peter D. Adams, Pier Lorenzo Puri, Rolf Bodmer

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DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation by Douglas J. MacKenzie, Neil A. Robertson, Iqbal Rather, Claire Reid, Gintare Sendzikaite, Hazel Cruickshanks, Tony McBryan, Andrew Hodges, Catrin Pritchard, Karen Blyth, Peter D. Adams

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Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment by Tina Wang, Brian Tsui, Jason F. Kreisberg, Neil A. Robertson, Andrew M. Gross, Michael Ku Yu, Hannah Carter, Holly M. Brown-Borg, Peter D. Adams, Trey Ideker

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The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. by Steven McFarlane, Anne Orr, Ashley P E Roberts, Kristen L Conn, Victor Iliev, Colin Loney, Ana da Silva Filipe, Katherine Smollett, Quan Gu, Neil Robertson, Peter D Adams, Taranjit Singh Rai, Chris Boutell

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Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions by John J. Cole, Neil A. Robertson, Mohammed Iqbal Rather, John P. Thomson, Tony McBryan, Duncan Sproul, Tina Wang, Claire Brock, William Clark, Trey Ideker, Richard R. Meehan, Richard A. Miller, Holly M. Brown-Borg, Peter D. Adams

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Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells by Maria A. Missinato, Sean Murphy, Michaela Lynott, Michael S. Yu, Anaïs Kervadec, Yu-Ling Chang, Suraj Kannan, Mafalda Loreti, Christopher Lee, Prashila Amatya, Hiroshi Tanaka, Chun-Teng Huang, Pier Lorenzo Puri, Chulan Kwon, Peter D. Adams, Li Qian, Alessandra Sacco, Peter Andersen, Alexandre R. Colas

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PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer by Tânia D. F. Costa, Ting Zhuang, Julie Lorent, Emilia Turco, Helene Olofsson, Miriam Masia-Balague, Miao Zhao, Parisa Rabieifar, Neil Robertson, Raoul Kuiper, Jonas Sjölund, Matthias Spiess, Pablo Hernández-Varas, Uta Rabenhorst, Pernilla Roswall, Ran Ma, Xiaowei Gong, Johan Hartman, Kristian Pietras, Peter D. Adams, Paola Defilippi, Staffan Strömblad

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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion by Jennifer L. Hope, Dennis C. Otero, Eun-Ah Bae, Christopher J. Stairiker, Ashley B. Palete, Hannah A. Faso, Michelle Lin, Monique L. Henriquez, Sreeja Roy, Hyungseok Seo, Xue Lei, Eric S. Wang, Savio Chow, Roberto Tinoco, Gregory A. Daniels, Kevin Yip, Alexandre Rosa Campos, Jun Yin, Peter D. Adams, Anjana Rao, Linda M. Bradley

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Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest by Dina Dikovskaya, John J. Cole, Susan M. Mason, Colin Nixon, Saadia A. Karim, Lynn McGarry, William Clark, Rachael N. Hewitt, Morgan A. Sammons, Jiajun Zhu, Dimitris Athineos, Joshua D.G. Leach, Francesco Marchesi, John van Tuyn, Stephen W. Tait, Claire Brock, Jennifer P. Morton, Hong Wu, Shelley L. Berger, Karen Blyth, Peter D. Adams

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