A label‐free impedance assay in endothelial cells differentiates the activation and desensitization properties of clinical S1P1 agonists by Patrick Grailhe, Asma Boutarfa‐Madec, Philippe Beauverger, Philip Janiak, Ashfaq A. Parkar

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Generation of iPSC line from MYH7 R403L mutation carrier with severe hypertrophic cardiomyopathy and isogenic CRISPR/Cas9 corrected control by Vincent Fontaine, Laetitia Duboscq-Bidot, Charlène Jouve, Matthieu Hamlin, Angélique Curjol, Véronique Briand, Philip Janiak, Jean-Sébastien Hulot, Marie-Pierre Pruniaux-Harnist, Philippe Charron, Eric Villard

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A G-protein-biased S1P1 agonist, SAR247799, improved LVH and diastolic function in a rat model of metabolic syndrome by Maria Francesca Evaristi, Bruno Poirier, Xavier Chénedé, Anne-Marie Lefebvre, Alain Roccon, Florence Gillot, Sandra Beeské, Alain Corbier, Marie-Pierre Pruniaux-Harnist, Philip Janiak, Ashfaq A. Parkar

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High Glucose Activates YAP Signaling to Promote Vascular Inflammation by Jeremy Ortillon, Jean-Christophe Le Bail, Elise Villard, Bertrand Léger, Bruno Poirier, Christine Girardot, Sandra Beeske, Laetitia Ledein, Véronique Blanchard, Patrice Brieu, Souâd Naimi, Philip Janiak, Etienne Guillot, Marco Meloni

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The oral Ca/calmodulin‐dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure by Julian Mustroph, Marzena Drzymalski, Maria Baier, Steffen Pabel, Alexander Biedermann, Bernadette Memmel, Melanie Durczok, Stefan Neef, Can Martin Sag, Bernhard Floerchinger, Leopold Rupprecht, Christof Schmid, York Zausig, Guillaume Bégis, Veronique Briand, Marie‐Laure Ozoux, Dorothee Tamarelle, Veronique Ballet, Philip Janiak, Philippe Beauverger, Lars S. Maier, Stefan Wagner

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Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models by Stephane Illiano, Bruno Poirier, Claire Minoletti, Olivier Pasquier, Laurence Riva, Xavier Chenede, Isabelle Menguy, Michel Guillotel, Philippe Prigent, Stéphane Le Claire, Florence Gillot, Gilbert Thill, François Lo Presti, Alain Corbier, Jean-Christophe Le Bail, Patrick Grailhe, Edith Monteagudo, Raffaele Ingenito, Elisabetta Bianchi, Christophe Philippo, Olivier Duclos, Sergio Mallart, Ross Bathgate, Philip Janiak

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PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo by Elise F. Villard, PhD, Aurélie Thedrez, PhD, Jorg Blankenstein, PhD, Mikaël Croyal, BSc, Thi-Thu-Trang Tran, PhD, Bruno Poirier, PhD, Jean-Christophe Le Bail, PhD, Stéphane Illiano, PhD, Estelle Nobécourt, MD, PhD, Michel Krempf, MD, PhD, Dirk J. Blom, MD, PhD, A. David Marais, MD, Philip Janiak, PhD, Anthony J. Muslin, MD, PhD, Etienne Guillot, PhD, Gilles Lambert, PhD

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