Seize the engine: Emerging cell cycle targets in breast cancer by Jesús Fuentes‐Antrás, Philippe L. Bedard, David W. Cescon

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Addressing racial and ethnic disparities in AACR project GENIE by Shawn M. Sweeney, Jessica A. Lavery, Hannah E. Fuchs, Jocelyn A. Lee, Samantha Brown, Katherine S. Panageas, Charles L. Sawyers, Philippe L. Bedard

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Evaluation of liver enzyme elevations and hepatotoxicity in patients treated with checkpoint inhibitor immunotherapy. by Morven Cunningham, Marco Iafolla, Yada Kanjanapan, Orlando Cerocchi, Marcus Butler, Lillian L Siu, Philippe L Bedard, Kendra Ross, Bettina Hansen, Anna Spreafico, Jordan J Feld

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Predicting response and toxicity to PD-1 inhibition using serum autoantibodies identified from immuno-mass spectrometry [version 1; peer review: 2 approved] by Milena Music, Marco Iafolla, Antoninus Soosaipillai, Ihor Batruch, Ioannis Prassas, Melania Pintilie, Aaron R. Hansen, Philippe L. Bedard, Stephanie Lheureux, Anna Spreafico, Albiruni Abdul Razak, Lillian L. Siu, Eleftherios P. Diamandis

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Clinical integration of germline findings from a tumor testing precision medicine program by Maria Carolina Sanabria-Salas, Nina C. Anggala, Brittany Gillies, Kirsten M. Farncombe, Renee Hofstedter, Larissa Peck, Helia Purnaghshband, Laura Redondo, Emily Thain, Wei Xu, Peter Sabatini, Philippe L. Bedard, Raymond H. Kim

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The Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Metastatic Testicular Cancer by Domen Ribnikar, Igor Stukalin, Philippe L. Bedard, Robert J. Hamilton, Michael Jewett, Padraig Warde, Peter Chung, Lynn Anson-Cartwright, Arnoud J. Templeton, Eitan Amir, Aaron R. Hansen, Daniel Y. C. Heng, Jeremy Lewin

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Phase IB study of ziv-aflibercept plus pembrolizumab in patients with advanced solid tumors by Howard Streicher, Elad Sharon, Mariano Severgnini, Michael Manos, Anita Giobbie-Hurder, F Stephen Hodi, Andrew S Brohl, Philippe L Bedard, Kevin Tyan, Scott Rodig, Osama E Rahma, Daniel J Renouf, Emma Hathaway, Rachel Cunningham

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Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis by Debra Van Egeren, Khushi Kohli, Jeremy L. Warner, Philippe L. Bedard, Gregory Riely, Eva Lepisto, Deborah Schrag, Michele LeNoue-Newton, Paul Catalano, Kenneth L. Kehl, Franziska Michor, for the AACR Project GENIE Consortium represented by Shawn Sweeney

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First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid... by Ravit Geva, Jennifer Mataraza, Osama Rahma, Jason John Luke, Philippe L Bedard, Sarina A Piha-Paul, Angad Singh, Tira J Tan, Darren WT Lim, Cinta Hierro, Toshikiko Doi, Alexander Lesokhin, Javier Otero, Lisa Nardi, Alexandros Xyrafas, Xinhui Chen

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Cancer patients’ experiences with immune checkpoint modulators: A qualitative study by Kari Ala‐Leppilampi, Natalie A. Baker, Chris McKillop, Marcus O. Butler, Lillian L. Siu, Anna Spreafico, Albiruni R. Abdul Razak, Anthony M. Joshua, David Hogg, Philippe L. Bedard, Natasha Leighl, Amit M. Oza, Janet A. Parsons, Aaron R. Hansen

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Longitudinal evaluation of circulating tumor DNA in patients undergoing neoadjuvant therapy for early breast cancer using a tumor-informed assay by Mitchell J. Elliott, Philippe Echelard, Christodoulos Pipinikas, Sasha Main, Jesús Fuentes Antrás, Aaron Dou, Zachary Veitch, Eitan Amir, Michelle B. Nadler, Nicholas Meti, Eshetu Atenafu, Elizabeth Shah, Celeste Yu, Nathan Campbell, Robert Ventura, Lillian L. Siu, Philippe L. Bedard, Hal K. Berman, David W. Cescon

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Tumor reactive γδ T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient by Scott C. Lien, Dalam Ly, S. Y. Cindy Yang, Ben X. Wang, Derek L. Clouthier, Michael St. Paul, Ramy Gadalla, Babak Noamani, Carlos R. Garcia-Batres, Sarah Boross-Harmer, Philippe L. Bedard, Trevor J. Pugh, Anna Spreafico, Naoto Hirano, Albiruni R. A. Razak, Pamela S. Ohashi

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Additional germline findings from a tumor profiling program by Neda Stjepanovic, Tracy L. Stockley, Philippe L. Bedard, Jeanna M. McCuaig, Melyssa Aronson, Spring Holter, Kara Semotiuk, Natasha B. Leighl, Raymond Jang, Monika K. Krzyzanowska, Amit M. Oza, Abha Gupta, Christine Elser, Lailah Ahmed, Lisa Wang, Suzanne Kamel-Reid, Lillian L. Siu, Raymond H. Kim

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A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-... by Kerry Lynn Reynolds, Philippe L. Bedard, Se-Hoon Lee, Chia-Chi Lin, Josep Tabernero, Maria Alsina, Ezra Cohen, José Baselga, George Blumenschein, Donna M. Graham, Ignacio Garrido-Laguna, Dejan Juric, Sunil Sharma, Ravi Salgia, Abdelkader Seroutou, Xianbin Tian, Rose Fernandez, Alex Morozov, Qing Sheng, Thiruvamoor Ramkumar, Angela Zubel, Yung-Jue Bang

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Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT) by Sofia Genta, Katherine Lajkosz, Noelle R. Yee, Pavlina Spiliopoulou, Alya Heirali, Aaron R. Hansen, Lillian L. Siu, Sam Saibil, Lee-Anne Stayner, Maryia Yanekina, Maxwell B. Sauder, Sareh Keshavarzi, Abdulazeez Salawu, Olga Vornicova, Marcus O. Butler, Philippe L. Bedard, Albiruni R. Abdul Razak, Robert Rottapel, Andrzej Chruscinski, Bryan Coburn, Anna Spreafico

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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction by Pei Jye Voon, Eric X. Chen, Helen X. Chen, Albert C. Lockhart, Solmaz Sahebjam, Karen Kelly, Ulka N. Vaishampayan, Vivek Subbiah, Albiruni R. Razak, Daniel J. Renouf, Sebastien J. Hotte, Arti Singh, Philippe L. Bedard, Aaron R. Hansen, S. Percy Ivy, Lisa Wang, Lee-Anne Stayner, Lillian L. Siu, Anna Spreafico

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Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab by Wei Xu, Anna Spreafico, Stephanie Lheureux, Marcus O Butler, Aaron R Hansen, Eric Chen, Ben Wang, Philippe L Bedard, Albiruni Abdul Razak, Dave Cescon, Lillian L Siu, Tak W Mak, Geoffrey Alan Watson, Enrique Sanz-Garcia, Wen-Jiang Zhang, Zhihui Amy Liu, SY Cindy Yang, Shaofeng Liu, Shawn Kubli, Hal Berman, Thomas Pfister, Sofia Genta

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Impact on costs and outcomes of multi-gene panel testing for advanced solid malignancies: a cost-consequence analysis using linked administrative dataResearch in context by Alberto Hernando-Calvo, Paul Nguyen, Philippe L. Bedard, Kelvin K.W. Chan, Ramy R. Saleh, Deirdre Weymann, Celeste Yu, Eitan Amir, Dean A. Regier, Bishal Gyawali, Danielle Kain, Brooke Wilson, Craig C. Earle, Nicole Mittmann, Albiruni R. Abdul Razak, Wanrudee Isaranuwatchai, Peter Sabatini, Anna Spreafico, Tracy L. Stockley, Trevor J. Pugh, Christine Williams, Lillian L. Siu, Timothy P. Hanna

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Large retroperitoneal lymphadenopathy and increased risk of venous thromboembolism in patients receiving first‐line chemotherapy for metastatic germ cell tumors: A study by the glo... by Ben Tran, Jose M. Ruiz‐Morales, Enrique Gonzalez‐Billalabeitia, Anna Patrikidou, Eitan Amir, Christoph Seidel, Carsten Bokemeyer, Christian Fankhauser, Thomas Hermanns, Alexey Rumyantsev, Alexey Tryakin, Margarida Brito, Aude Fléchon, Edmond Michael Kwan, Tina Cheng, Daniel Castellano, Xavier Garcia del Muro, Anis A. Hamid, Margaret Ottaviano, Giovannella Palmieri, Robert Kitson, Alison Reid, Daniel Y. C. Heng, Philippe L. Bedard

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An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors by Neda Stjepanovic, Amit M Oza, Anna Spreafico, Stephanie Lheureux, Marcus O Butler, Pamela S Ohashi, Kirsty Taylor, Helen Loo Yau, Ankur Chakravarthy, Ben Wang, Shu Yi Shen, Ilias Ettayebi, Charles A Ishak, Philippe L Bedard, Albiruni Abdul Razak, Aaron R Hansen, Dave Cescon, Brendan Van As, Sarah Boross-Harmer, Lisa Wang, Trevor J Pugh, Lillian L Siu, Daniel D De Carvalho

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