The New Immuno-Oncology-Based Therapies and Their Perspectives in Hepatocellular Carcinoma by Philippe Merle

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Reply to Rizzo et al. by Arndt Vogel, Javier Sanchez Alvarez, Monica Daigl, Philippe Merle

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Regorafenib vs. cabozantinib as second-line treatment for advanced hepatocellular carcinoma: an anchored matching-adjusted indirect comparison of efficacy and safety by Philippe Merle, Masatoshi Kudo, Stanimira Krotneva, Kirhan Ozgurdal, Yun Su, Irina Proskorovsky

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Case Report: Successful liver transplantation after achieving complete clinical remission of advanced HCC with Atezolizumab plus Bevacizumab combination therapy by Yasmina Chouik, Yasmina Chouik, Domitille Erard, Domitille Erard, Hassan Demian, Thomas Schulz, Tessa Mazard, Kerstin Hartig-Lavie, Teresa Antonini, Jean-Yves Mabrut, Jean-Yves Mabrut, Kayvan Mohkam, Kayvan Mohkam, Agnès Rode, Philippe Merle, Philippe Merle

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Atezolizumab Plus Bevacizumab vs Sorafenib for Unresectable Hepatocellular Carcinoma: Results From Older Adults Enrolled in the IMbrave150 Randomized Clinical Trial by Daneng Li, Han Chong Toh, Philippe Merle, Kaoru Tsuchiya, Sairy Hernandez, Wendy Verret, Alan Nicholas, Masatoshi Kudo

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Predictive and prognostic potential of liver function assessment in patients with advanced hepatocellular carcinoma: a systematic literature review by Arndt Vogel, Robin Kate Kelley, Philip Johnson, Philippe Merle, Thomas Yau, Masatoshi Kudo, Tim Meyer, Lorenza Rimassa

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Copper Isotope Evidence of Oxidative Stress–Induced Hepatic Breakdown and the Transition to Hepatocellular Carcinoma by Philippe Telouk, Marie-Laure Plissonnier, Philippe Merle, Fabien Zoulim, Nadim Fares, Paule Guilloreau, Romain Parent, Justine Bacchetta, Marc Danan, Sergio Carandina, Francis Albarède, PhD

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Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting by Manon Falette-Puisieux, Jean-Charles Nault, Mohamed Bouattour, Marie Lequoy, Giuliana Amaddeo, Thomas Decaens, Frederic Di Fiore, Sylvain Manfredi, Philippe Merle, Aurore Baron, Christophe Locher, Anna Pellat, Romain Coriat

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Evaluation of postoperative ascites after somatostatin infusion following hepatectomy for hepatocellular carcinoma by laparotomy: a multicenter randomized double-blind controlled t... by Kayvan Mohkam, Michel Rayar, Jean-Philippe Adam, Fabrice Muscari, Agnès Rode, Philippe Merle, Pierre Pradat, Stéphanie Bauler, Isabelle Delfour, Laurence Chiche, Christian Ducerf, Karim Boudjema, Mickaël Lesurtel, Christophe Laurent, Jean-Yves Mabrut

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362 Association of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio with clinical outcomes to tislelizumab monotherapy in patients with previously treated advanced h... by Yong Liu, Richard Hubner, Ruiqi Huang, Yee Chao, Ying Cheng, Zhirong Shen, Xikun Wu, Congying Xie, Bai Li, Chen Ling, Philippe MERLE, Jane Margetts, Helena Verdaguer Mata, Cong Fei, Sandra Chica Duque, Zhenggang Ren

Comparative Efficacy of Atezolizumab plus Bevacizumab and Other Treatment Options for Patients with Unresectable Hepatocellular Carcinoma: A Network Meta-Analysis by Arndt Vogel, Lorenza Rimassa, Hui-Chan Sun, Ghassan K. Abou-Alfa, Anthony El-Khoueiry, David J. Pinato, Javier Sanchez Alvarez, Monica Daigl, Panos Orfanos, Michael Leibfried, Marie-Hélène Blanchet Zumofen, Vincent E. Gaillard, Philippe Merle

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First-in-human effects of PPT1 inhibition using the oral treatment with GNS561/ Ezurpimtrostat in patients with primary and secondary liver cancers by James J. Harding, Ahmad Awada, Gael Roth, Thomas Decaens, Philippe Merle, Nuria Kotecki, Chantal Dreyer, Christelle Ansaldi, Madani Rachid, Soraya Mezouar, Agnes Menut, Eloïne Nadeige Bestion, Valérie Paradis, Philippe Halfon, Ghassan K. Abou-Alfa, Eric Raymond

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ALBI score and outcomes in patients with hepatocellular carcinoma: analysis of the randomized controlled trial KEYNOTE-240 by Arndt Vogel, Philippe Merle, Chris Verslype, Richard S. Finn, Andrew X. Zhu, Ann-Lii Cheng, Stephen Lam Chan, Thomas Yau, Baek-Yeol Ryoo, Jennifer Knox, Bruno Daniele, Shukui Qin, Ziwen Wei, Yanna Miteva, Usha Malhotra, Abby B. Siegel, Masatoshi Kudo

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Outcomes Based on Plasma Biomarkers for the Phase 3 CELESTIAL Trial of Cabozantinib versus Placebo in Advanced Hepatocellular Carcinoma by Lorenza Rimassa, Robin Kate Kelley, Tim Meyer, Baek-Yeol Ryoo, Philippe Merle, Joong-Won Park, Jean-Frederic Blanc, Ho Yeong Lim, Albert Tran, Yi-Wah Chan, Paul McAdam, Evelyn Wang, Ann-Lii Cheng, Anthony B. El-Khoueiry, Ghassan K. Abou-Alfa

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Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer-Term Follow-Up From the Phase 3 KEYNOTE-240 Trial by Philippe Merle, Masatoshi Kudo, Julien Edeline, Mohamed Bouattour, Ann-Lii Cheng, Stephen Lam Chan, Thomas Yau, Marcelo Garrido, Jennifer Knox, Bruno Daniele, Valeriy Breder, Ho Yeong Lim, Sadahisa Ogasawara, Stéphane Cattan, Yee Chao, Abby B. Siegel, Iván Martinez-Forero, Ziwen Wei, Chih-Chin Liu, Richard S. Finn

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TACE and conformal radiotherapy vs. TACE alone for hepatocellular carcinoma: A randomised controlled trial by Cyrille Féray, Loic Campion, Philippe Mathurin, Isabelle Archambreaud, Xavier Mirabel, Jean Pierre Bronowicki, Emmanuel Rio, Christophe Perret, Laurent Mineur, Frédéric Oberti, Yann Touchefeu, Jérôme Gournay, Hélène Regnault, Julien Edeline, Agnès Rode, Patrick Hillion, Jean Frédéric Blanc, Eric Nguyen Khac, Daniel Azoulay, Alain Luciani, Athena Galetto Preglisasco, Elodie Faurel-Paul, Hélène Auble, Françoise Mornex, Philippe Merle

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Tislelizumab in Patients with Previously Treated Advanced Hepatocellular Carcinoma (RATIONALE-208): A Multicenter, Non-Randomized, Open-Label, Phase 2 Trial by Zhenggang Ren, Michel Ducreux, Ghassan K. Abou-Alfa, Philippe Merle, Weijia Fang, Julien Edeline, Zhiwei Li, Lihua Wu, Eric Assenat, Sheng Hu, Lorenza Rimassa, Tao Zhang, Jean-Frédéric Blanc, Hongming Pan, Paul Ross, Chia-Jui Yen, Albert Tran, Guoliang Shao, Mohamed Bouattour, Yajin Chen, Tim Meyer, Jinlin Hou, David Tougeron, Yuxian Bai, Ming-Mo Hou, Zhiqiang Meng, John Wu, Vincent Li, Sandra Chica-Duque, Ann-Lii Cheng

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Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic you... by Narcisse Patrice Komas, Sumantra Ghosh, Mariama Abdou-Chekaraou, Pierre Pradat, Nasser Al Hawajri, Alexandre Manirakiza, Gina Laure Laghoe, Claudine Bekondi, Ségolène Brichler, Jean-Omer Ouavéné, Abdoulaye Sépou, Brice Martial Yambiyo, Jean Chrysostome Gody, Valentin Fikouma, Athénais Gerber, Natali Abeywickrama Samarakoon, Dulce Alfaiate, Caroline Scholtès, Nora Martel, Frédéric Le Gal, Hugo Lo Pinto, Ikram Amri, Olivier Hantz, David Durantel, Jean-Louis Lesbordes, Emmanuel Gordien, Philippe Merle, Tudor Drugan, Christian Trépo, Fabien Zoulim, Jean-Claude Cortay, Alan Campbell Kay, Paul Dény

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Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium chann... by Hugo Jimenez, Minghui Wang, Jacquelyn W. Zimmerman, Michael J. Pennison, Sambad Sharma, Trevor Surratt, Zhi-Xiang Xu, Ivan Brezovich, Devin Absher, Richard M. Myers, Barry DeYoung, David L. Caudell, Dongquan Chen, Hui-Wen Lo, Hui-Kuan Lin, Dwayne W. Godwin, Michael Olivier, Anand Ghanekar, Kui Chen, Lance D. Miller, Yijian Gong, Myles Capstick, Ralph B. D'Agostino, Jr, Reginald Munden, Philippe Merle, Alexandre Barbault, Arthur W. Blackstock, Herbert L. Bonkovsky, Guang-Yu Yang, Guangxu Jin, Liang Liu, Wei Zhang, Kounosuke Watabe, Carl F. Blackman, Boris C. Pasche

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