Arguments to Support a Viral Origin of Oral Squamous Cell Carcinoma in Non-Smoker and Non-Drinker Patients by Jean-Philippe Foy, Jean-Philippe Foy, Jean-Philippe Foy, Chloé Bertolus, David Boutolleau, David Boutolleau, Henri Agut, Henri Agut, Antoine Gessain, Zdenko Herceg, Pierre Saintigny, Pierre Saintigny, Pierre Saintigny

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Precision Medicine Approaches to Overcome Resistance to Therapy in Head and Neck Cancers by Sandra Ortiz-Cuaran, Jebrane Bouaoud, Jebrane Bouaoud, Jebrane Bouaoud, Andy Karabajakian, Andy Karabajakian, Jérôme Fayette, Jérôme Fayette, Pierre Saintigny, Pierre Saintigny

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mTOR Signalling in Head and Neck Cancer: Heads Up by Fiona H. Tan, Yuchen Bai, Pierre Saintigny, Charbel Darido

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Radiomics combined with transcriptomics to predict response to immunotherapy from patients treated with PD-1/PD-L1 inhibitors for advanced NSCLC by Amine Bouhamama, Amine Bouhamama, Benjamin Leporq, Khuram Faraz, Jean-Philippe Foy, Maxime Boussageon, Maurice Pérol, Sandra Ortiz-Cuaran, François Ghiringhelli, Pierre Saintigny, Pierre Saintigny, Olivier Beuf, Frank Pilleul, Frank Pilleul

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EZH2 promotes malignant behaviors via cell cycle dysregulation and its mRNA level associates with prognosis of patient with non-small cell lung cancer. by Wei Cao, Rachel de Oliveira Ribeiro, Diane Liu, Pierre Saintigny, Ronghui Xia, Yuwen Xue, Ruxian Lin, Li Mao, Hening Ren

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Gene Expression Clustering and Selected Head and Neck Cancer Gene Signatures Highlight Risk Probability Differences in Oral Premalignant Lesions by Andrea Carenzo, Mara S. Serafini, Elisa Roca, Alberto Paderno, Davide Mattavelli, Chiara Romani, Pierre Saintigny, Senada Koljenović, Lisa Licitra, Loris De Cecco, Paolo Bossi

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Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. by Marie Ménard, Clélia Costechareyre, Gabriel Ichim, Jonathan Blachier, David Neves, Loraine Jarrosson-Wuilleme, Reinhard Depping, Jan Koster, Pierre Saintigny, Patrick Mehlen, Servane Tauszig-Delamasure

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Non-canonical NOTCH3 signalling limits tumour angiogenesis by Shuheng Lin, Ana Negulescu, Sirisha Bulusu, Benjamin Gibert, Jean-Guy Delcros, Benjamin Ducarouge, Nicolas Rama, Nicolas Gadot, Isabelle Treilleux, Pierre Saintigny, Olivier Meurette, Patrick Mehlen

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Effect of acute aerobic exercise before immunotherapy and chemotherapy infusion in patients with metastatic non-small-cell lung cancer: protocol for the ERICA feasibility trial by Vincent Pialoux, Christophe Caux, Christine Ménétrier-Caux, Maurice Pérol, Thierry Walzer, Béatrice Fervers, Olivia Pérol, Lidia Delrieu, Pierre Saintigny, Manon Gouez, Marine Villard, Philippe Marijnen

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EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer by Lauriane Muller, Frédérique Fauvet, Christelle Chassot, Francesca Angileri, Angèle Coutant, Cyril Dégletagne, Laurie Tonon, Pierre Saintigny, Alain Puisieux, Anne-Pierre Morel, Maria Ouzounova, Pierre Martinez

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Expression Profiling of Ribosome Biogenesis Factors Reveals Nucleolin as a Novel Potential Marker to Predict Outcome in AML Patients. by Virginie Marcel, Frédéric Catez, Caroline M Berger, Emeline Perrial, Adriana Plesa, Xavier Thomas, Eve Mattei, Sandrine Hayette, Pierre Saintigny, Philippe Bouvet, Jean-Jacques Diaz, Charles Dumontet

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Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level by Chloe Goldsmith, Jesús Rafael Rodríguez-Aguilera, Ines El-Rifai, Adrien Jarretier-Yuste, Valérie Hervieu, Olivier Raineteau, Pierre Saintigny, Victoria Chagoya de Sánchez, Robert Dante, Gabriel Ichim, Hector Hernandez-Vargas

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A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes by Jean-Philippe Foy, Louis Bazire, Sandra Ortiz-Cuaran, Sophie Deneuve, Janice Kielbassa, Emilie Thomas, Alain Viari, Alain Puisieux, Patrick Goudot, Chloé Bertolus, Nicolas Foray, Youlia Kirova, Pierre Verrelle, Pierre Saintigny

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RSK3 switches cell fate: from stress-induced senescence to malignant progression by Anda Huna, Jean-Michel Flaman, Catalina Lodillinsky, Kexin Zhu, Gabriela Makulyte, Victoria Pakulska, Yohann Coute, Clémence Ruisseaux, Pierre Saintigny, Hector Hernandez-Vargas, Pierre-Antoine Defossez, Mathieu Boissan, Nadine Martin, David Bernard

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Added value of whole‐exome and RNA sequencing in advanced and refractory cancer patients with no molecular‐based treatment recommendation based on a 90‐gene panel by Armelle Dufresne, Valéry Attignon, Anthony Ferrari, Laurie Tonon, Sandrine Boyault, Séverine Tabone‐Eglinger, Philippe Cassier, Olivier Trédan, Nadège Corradini, Armelle Vinceneux, Aurélie Swalduz, Alain Viari, Sylvie Chabaud, David Pérol, Jean Yves Blay, Pierre Saintigny

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Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers by Marie Alexandra Albaret, Arnaud Paré, Lucie Malet, Geneviève De Souza, Emilie Lavergne, Dominique Goga, Gonzague De Pinieux, Claire Castellier, Aurélie Swalduz, Vivian Robin, Vincent Lavergne, Hichem-Claude Mertani, Isabelle Treilleux, Claudine Vermot-Desroches, Jean-Jacques Diaz, Pierre Saintigny

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Outcomes in oncogenic-addicted advanced NSCLC patients with actionable mutations identified by liquid biopsy genomic profiling using a tagged amplicon-based NGS assay. by Jordi Remon, Aurelie Swalduz, David Planchard, Sandra Ortiz-Cuaran, Laura Mezquita, Ludovic Lacroix, Cecile Jovelet, Etienne Rouleau, Camille Leonce, Frank De Kievit, Clive Morris, Greg Jones, Kelly Mercier, Karen Howarth, Emma Green, Maurice Pérol, Pierre Saintigny, Benjamin Besse

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Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer by Courèche-Guillaume Kaderbhai, Corentin Richard, Jean David Fumet, Anne Aarnink, Sandra Ortiz-Cuaran, Maurice Pérol, Pascal Foucher, Bruno Coudert, Laure Favier, Aurélie Lagrange, Emeric Limagne, Romain Boidot, Sylvain Ladoire, Michel Poudenx, Marius Ilie, Paul Hofman, Pierre Saintigny, François Ghiringhelli

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CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity by Maha Siouda, Audrey D. Dujardin, Laetitia Barbollat-Boutrand, Marco A. Mendoza-Parra, Benjamin Gibert, Maria Ouzounova, Jebrane Bouaoud, Laurie Tonon, Marie Robert, Jean-Philippe Foy, Vincent Lavergne, Serge N. Manie, Alain Viari, Alain Puisieux, Gabriel Ichim, Hinrich Gronemeyer, Pierre Saintigny, Peter Mulligan

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A WIN Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non‐small cell lung cancer by Benjamin Solomon, Ana Callejo, Jair Bar, Guy Berchem, Lyudmila Bazhenova, Pierre Saintigny, Fanny Wunder, Jacques Raynaud, Nicolas Girard, J. Jack Lee, Raed Sulaiman, Bruce Prouse, Catherine Bresson, Hila Ventura, Shai Magidi, Eitan Rubin, Brandon Young, Amir Onn, Brian Leyland‐Jones, Richard L. Schilsky, Vladimir Lazar, Enriqueta Felip, Razelle Kurzrock

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