Conformational Entropy as a Potential Liability of Computationally Designed Antibodies by Thomas Löhr, Pietro Sormanni, Michele Vendruscolo

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An open-source automated PEG precipitation assay to measure the relative solubility of proteins with low material requirement by Marc Oeller, Pietro Sormanni, Michele Vendruscolo

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Editorial: Intrinsically Disordered Proteins and Regions: The Challenge to the Structure-Function Relationship by Angelo Toto, Pietro Sormanni, Cristina Paissoni, Vladimir N. Uversky

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Rapid and accurate in silico solubility screening of a monoclonal antibody library by Pietro Sormanni, Leanne Amery, Sofia Ekizoglou, Michele Vendruscolo, Bojana Popovic

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Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties by Hristo L. Svilenov, Paolo Arosio, Tim Menzen, Peter Tessier, Pietro Sormanni

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Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures by Tatsuya Ikenoue, Francesco A. Aprile, Francesco A. Aprile, Pietro Sormanni, Michele Vendruscolo

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Automated optimization of the solubility of a hyper-stable α-amylase by Montader Ali, Matthew Greenig, Marc Oeller, Misha Atkinson, Xing Xu, Pietro Sormanni

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Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt by Aubin Ramon, Mingyang Ni, Olga Predeina, Rebecca Gaffey, Patrick Kunz, Shimobi Onuoha, Pietro Sormanni

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Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease by Rosie Freer, Pietro Sormanni, Prajwal Ciryam, Burkhard Rammner, Silvio O. Rizzoli, Christopher M. Dobson, Michele Vendruscolo

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Automated optimisation of solubility and conformational stability of antibodies and proteins by Angelo Rosace, Anja Bennett, Marc Oeller, Mie M. Mortensen, Laila Sakhnini, Nikolai Lorenzen, Christian Poulsen, Pietro Sormanni

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A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data. by Ajeet K Sharma, Pietro Sormanni, Nabeel Ahmed, Prajwal Ciryam, Ulrike A Friedrich, Günter Kramer, Edward P O'Brien

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Sequence-based prediction of the intrinsic solubility of peptides containing non-natural amino acids by Marc Oeller, Ryan J. D. Kang, Hannah L. Bolt, Ana L. Gomes dos Santos, Annika Langborg Weinmann, Antonios Nikitidis, Pavol Zlatoidsky, Wu Su, Werngard Czechtizky, Leonardo De Maria, Pietro Sormanni, Michele Vendruscolo

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Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms by Suman De, David C. Wirthensohn, Patrick Flagmeier, Craig Hughes, Francesco A. Aprile, Francesco S. Ruggeri, Daniel R. Whiten, Derya Emin, Zengjie Xia, Juan A. Varela, Pietro Sormanni, Franziska Kundel, Tuomas P. J. Knowles, Christopher M. Dobson, Clare Bryant, Michele Vendruscolo, David Klenerman

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Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity by Tanguy Le Marchand, Matteo de Rosa, Nicola Salvi, Benedetta Maria Sala, Loren B. Andreas, Emeline Barbet-Massin, Pietro Sormanni, Alberto Barbiroli, Riccardo Porcari, Cristiano Sousa Mota, Daniele de Sanctis, Martino Bolognesi, Lyndon Emsley, Vittorio Bellotti, Martin Blackledge, Carlo Camilloni, Guido Pintacuda, Stefano Ricagno

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Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease by Michele Perni, Annemieke van der Goot, Ryan Limbocker, Ryan Limbocker, Tjakko J. van Ham, Francesco A. Aprile, Catherine K. Xu, Patrick Flagmeier, Karen Thijssen, Pietro Sormanni, Giuliana Fusco, Serene W. Chen, Pavan K. Challa, Julius B. Kirkegaard, Romain F. Laine, Kai Yu Ma, Kai Yu Ma, Martin B. D. Müller, Martin B. D. Müller, Tessa Sinnige, Janet R. Kumita, Samuel I. A. Cohen, Renée Seinstra, Gabriele S. Kaminski Schierle, Clemens F. Kaminski, Denise Barbut, Alfonso De Simone, Tuomas P. J. Knowles, Michael Zasloff, Ellen A. A. Nollen, Michele Vendruscolo, Christopher M. Dobson

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