569 Targeting IL-15 delivery to PD-L1 expressing tumors with an Anti-PD-L1-IL-15 cytokine fusion IgM to enhance T Cell and NK Cell Mediated tumor cytotoxicity by Angus Sinclair, Thierry Giffon, Dean Ng, Poonam Yakkundi, Hope Lancero, Marigold Manlusoc, Rodnie Rosete, Avneesh Saini, Madeline Tran, Kevin Carlin, Chitra Saraiya, Ramesh Baliga, Bruce Keyt

711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion... by Maya Kotturi, Mélanie Desbois, Angus Sinclair, Thierry Giffon, Dean Ng, Poonam Yakkundi, Marigold Manlusoc, Rodnie Rosete, Avneesh Saini, Bruce Keyt, Daniel Machado, Miho Oyasu, Susan Calhoun, Tasnim Kothambawala, Beatrice Wang

908 Humanized model for assessment of therapies targeting either lymphoid or myeloid compartment: enhanced evaluation of clinical relevancy & translatability by Charles Dumontet, Gaëlle Martin, Chloé Beuraud, Yacine Cherifi, Alexandre Fraichard, Patricia Isnard-Petit, Kader Thiam, Angus Sinclair, Poonam Yakkundi, Florence Renart-Depontieu, Morgane Denis, Léa Magadoux, Elsa Kress, Ludovic Bourre, Dean Campbell, Astrid Doerner

1174 Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity by Yue Wang, Jie Xue, Umesh Muchhal, Keyu Li, Angus Sinclair, Poonam Yakkundi, Rodnie Rosete, Bruce Keyt, Liqin Liu, Deepal Pandya, Vidhya Bai Krishnoji Rao, Elizabeth Perez, Paul Hinton, Gene Li, Kristene Mai, Nardeen Hanna, Zhongde Ye, Jinqiu Wang, Tina Mao, Palak Chudasama, Sachi Rahman, Zee Malik, Krzysztof Bzymek

1362 Agonistic 4–1BB IgM antibodies enhance CD8+ T cell proliferation and proinflammatory cytokine secretion in vitro and in vivo by Adam Smith, Umesh Muchhal, Dean Ng, Poonam Yakkundi, Gary Bolton, Yuan Cao, Tasnim Kothambawala, Beatrice Wang, Deepal Pandya, Vidhya Bai Krishnoji Rao, Elizabeth Perez, Paul Hinton, Hyewon Phee, Sachi Rahman, Thin Wai, Natalia L dos Santos, Aditya Bharti, Balaji Banoth, Harrison Horwitz, Bruce A Keyt, Angus M Sinclair