Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. by Kirstetter, P, Anderson, K, Porse, B, Jacobsen, SE, Nerlov, C

Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo. by Pedersen, T, Bereshchenko, O, Garcia-Silva, S, Ermakova, O, Kurz, E, Mandrup, S, Porse, B, Nerlov, C

Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency by Hasemann, MS, Schuster, M, Frank, A, Theilgaard-Mönch, K, Pedersen, T, Nerlov, C, Porse, B

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo. by Porse, B, Pedersen TA, Xu, X, Lindberg, B, Wewer, U, Friis-Hansen, L, Nerlov, C

Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage. by Porse, B, Bryder, D, Theilgaard-Mönch, K, Hasemann, MS, Anderson, K, Damgaard, I, Jacobsen, SE, Nerlov, C

The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo. by Porse, B, Pedersen, T, Hasemann, MS, Schuster, M, Kirstetter, P, Luedde, T, Damgaard, I, Kurz, E, Schjerling, C, Nerlov, C

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. by Weischenfeldt, J, Damgaard, I, Bryder, D, Theilgaard-Mönch, K, Thoren, L, Nielsen, F, Jacobsen, SE, Nerlov, C, Porse, B

Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen. by Hasemann, MS, Damgaard, I, Schuster, M, Theilgaard-Mönch, K, Sørensen, AB, Mrsic, A, Krugers, T, Ylstra, B, Pedersen, F, Nerlov, C, Porse, B

Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells. by Kirstetter, P, Schuster, M, Bereshchenko, O, Moore, S, Dvinge, H, Kurz, E, Theilgaard-Mönch, K, Månsson, R, Pedersen, T, Pabst, T, Schrock, E, Porse, B, Jacobsen, SE, Bertone, P, Tenen, D, Nerlov, C

Gene expression profiling in MDS and AML: potential and future avenues. by Theilgaard-Mönch, K, Boultwood, J, Ferrari, S, Giannopoulos, K, Hernandez-Rivas, J, Kohlmann, A, Morgan, M, Porse, B, Tagliafico, E, Zwaan, C, Wainscoat, J, Van den Heuvel-Eibrink, MM, Mills, K, Bullinger, L

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis by Li, R, Colombo, M, Wang, G, Rodriguez-Romera, A, Benlabiod, C, Jooss, NJ, O'Sullivan, J, Brierley, CK, Clark, S-A, Pérez Sáez, JM, Fernández, PA, Schoof, EM, Porse, B, Meng, Y, Khan, AO, Wen, S, Dong, P, Zhou, W, Sousos, N, Murphy, L, Clarke, M, Olijnik, A-A, Wong, ZC, Karali, CS, Sirinukunwattana, K, Ryou, H, Norfo, R, Cheng, Q, Carrelha, J, Ren, Z, Thongjuea, S, Rathinam, VA, Krishnan, A, Royston, D, Rabinovich, GA, Mead, AJ, Psaila, B

The EHA Research Roadmap: normal hematopoiesis by Jaffredo, T, Balduini, A, Bigas, A, Bernardi, R, Bonnet, D, Canque, B, Charbord, P, Cumano, A, Delwel, R, Durand, C, Fibbe, W, Forrester, L, de Franceschi, L, Ghevaert, C, Gjertsen, B, Gottgens, B, Graf, T, Heidenreich, O, Hermine, O, Higgs, D, Kleanthous, M, Klump, H, Kouskoff, V, Krause, D, Lacaud, G, Celso, CL, Martens, JHA, Méndez-Ferrer, S, Menendez, P, Oostendorp, R, Philipsen, S, Porse, B, Raaijmakers, M, Robin, C, Stunnenberg, H, Theilgaard-Mönch, K, Touw, I, Vainchenker, W, Corrons, J-LV, Yvernogeau, L, Schuringa, JJ