Discussion by Ratcliffe, P, Peet, D, Chandel, N, Semenza, G, Stolze, I, Pouysségur, J, Duchen, M, Ward, J, Murphy, M, Archer, S, Buckler, K, Schumacker, P

Discussion by Gonzalez, C, Ratcliffe, P, Acker, H, Archer, S, Duchen, M, Chandel, N, Buckler, K, Pouysségur, J, Kummer, W, Prabhakar, N, Schumacker, P, Sylvester, J, Semenza, G, Ward, J, López-Barneo, J, Harris, A