Systems level characterizations of single and combination drug mechanisms of action in vitro and in vivo by Pritchard, Justin (Justin Robert)

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Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes by Pritchard, Justin R., Zhao, Boyang

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Understanding resistance to combination chemotherapy by Pritchard, Justin R., Hemann, Michael, Lauffenburger, Douglas A

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Addressing Genetic Tumor Heterogeneity through Computationally Predictive Combination Therapy by Zhao, Boyang, Pritchard, Justin R., Hemann, Michael, Lauffenburger, Douglas A

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Predicting cancer drug mechanisms of action using molecular network signatures by Pritchard, Justin R., Bruno, Peter Michael, Hemann, Michael, Lauffenburger, Douglas A

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A mammalian functional-genetic approach to characterizing cancer therapeutics by Williams, Richard T., Jiang, Hai, Hemann, Michael, Pritchard, Justin R., Lauffenburger, Douglas A

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Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death by Wands, Jack R., Cosgrove, Benjamin D., Hemann, Michael, Pritchard, Justin R., Griffith, Linda G, Lauffenburger, Douglas A

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Defining principles of combination drug mechanisms of action by Bruno, Peter Michael, Gilbert, Luke Andrew, Capron, Kelsey L., Hemann, Michael, Pritchard, Justin R., Lauffenburger, Douglas A

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Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution by Zhao, Boyang, Srinivas, Raja Ram, Creixell Morera, Pau, Tidor, Bruce, Lauffenburger, Douglas A, Hemann, Michael, Pritchard, Justin R.

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BCL-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response by Gilbert, Luke Andrew, Meacham, Corbin Elizabeth, Jiang, Hai, Hemann, Michael, Pritchard, Justin R., Shingleton, Jennifer R., Lauffenburger, Douglas A

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The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning by Bruno, Peter M, Lu, Mengrou, Dennis, Kady A, Inam, Haider, Moore, Connor J, Sheehe, John, Elledge, Stephen J, Hemann, Michael T, Pritchard, Justin R

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A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress by Murai, Junko, Pommier, Yves, Hemann, Michael T, Bruno, Peter Michael, Liu, Yunpeng, Park, Ga Young, Koch, Catherine E., Lippard, Stephen J., Hemann, Michael, Eisen, Timothy Jonas, Pritchard, Justin R.

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A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth by Meacham, Corbin Elizabeth, Lawton, Lee N., Pritchard, Justin R., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Soto Feliciano, Yadira Marie, Hemann, Michael, Joughin, Brian Alan

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Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer by Dowling, Catríona M, Hollinshead, Kate ER, Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T, Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K, Bleach, Rachel, Lindner, Andreas U, Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen HM, Wynne, Kieran, Hemann, Michael, Bradner, James E, Kimmelman, Alec C, Guerriero, Jennifer L, Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G, Chonghaile, Tríona Ní

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Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer by Dowling, Catríona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Tríona Ní

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