The influence of antigenic variation on cytotoxic T lymphocyte responses in HIV-1 infection. ‌ Price, D, Meier, U, Klenerman, P, Purbhoo, M, Phillips, R, Sewell, A

Copresentation of natural HIV-1 agonist and antagonist ligands fails to induce the T cell receptor signaling cascade. ‌ Purbhoo, M, Sewell, A, Klenerman, P, Goulder, P, Hilyard, K, Bell, J, Jakobsen, B, Phillips, R

Antagonism of cytotoxic T-lymphocyte activation by soluble CD8. ‌ Sewell, A, Gerth, U, Price, D, Purbhoo, M, Boulter, J, Gao, G, Bell, J, Phillips, R, Jakobsen, B

Ultrasensitive detection and phenotyping of CD4+ T cells with optimized HLA class II tetramer staining. ‌ Scriba, T, Purbhoo, M, Day, C, Robinson, N, Fidler, S, Fox, J, Weber, J, Klenerman, P, Sewell, A, Phillips, R

Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent. ‌ Whelan, J, Dunbar, P, Price, D, Purbhoo, M, Lechner, F, Ogg, G, Griffiths, G, Phillips, R, Cerundolo, V, Sewell, A

The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. ‌ Purbhoo, M, Boulter, J, Price, D, Vuidepot, A, Hourigan, C, Dunbar, P, Olson, K, Dawson, S, Phillips, R, Jakobsen, B, Bell, J, Sewell, A

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. ‌ Sowinski, S, Jolly, C, Berninghausen, O, Purbhoo, M, Chauveau, A, Köhler, K, Oddos, S, Eissmann, P, Brodsky, F, Hopkins, C, Onfelt, B, Sattentau, Q, Davis, D

Quantifying and imaging NY-ESO-1/LAGE-1-derived epitopes on tumor cells using high affinity T cell receptors. ‌ Purbhoo, M, Sutton, D, Brewer, J, Mullings, R, Hill, M, Mahon, T, Karbach, J, Jäger, E, Cameron, B, Lissin, N, Vyas, P, Chen, J, Cerundolo, V, Jakobsen, B

A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex. ‌ Xu, X, Purbhoo, M, Chen, N, Mongkolsapaya, J, Cox, J, Meier, U, Tafuro, S, Dunbar, P, Sewell, A, Hourigan, C, Appay, V, Cerundolo, V, Burrows, SR, Mcmichael, A, Screaton, G

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor. ‌ Varela-Rohena, A, Molloy, P, Dunn, S, Li, Y, Suhoski, M, Carroll, R, Milicic, A, Mahon, T, Sutton, D, Laugel, B, Moysey, R, Cameron, B, Vuidepot, A, Purbhoo, M, Cole, D, Phillips, R, June, C, Jakobsen, B, Sewell, A, Riley, J