Modeling mixed-lineage-rearranged leukemia initiation in CD34+ cells: a “CRISPR” solution by Raúl Torres-Ruiz, Sandra Rodriguez-Perales, Clara Bueno, Pablo Menendez

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The “Never-Ending” Mouse Models for MLL-Rearranged Acute Leukemia Are Still Teaching Us by Katrin Ottersbach, Alejandra Sanjuan-Pla, Raúl Torres-Ruíz, Clara Bueno, Talia Velasco-Hernández, Pablo Menendez

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Functional characterization of two enhancers located downstream FOXP2 by Raúl Torres-Ruiz, Antonio Benítez-Burraco, Marta Martínez-Lage, Sandra Rodríguez-Perales, Paloma García-Bellido

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OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells by Juan Miguel Baquero, Erik Marchena-Perea, Rocío Mirabet, Raúl Torres-Ruiz, Raúl Torres-Ruiz, Carmen Blanco-Aparicio, Sandra Rodríguez-Perales, Thomas Helleday, Thomas Helleday, Carlos Benítez-Buelga, Javier Benítez, Javier Benítez, Ana Osorio, Ana Osorio, Ana Osorio

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RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment by Alvaro Torres-Gomez, Jose Luis Sanchez-Trincado, Víctor Toribio, Raul Torres-Ruiz, Sandra Rodríguez-Perales, María Yáñez-Mó, Pedro A. Reche, Carlos Cabañas, Esther M. Lafuente

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Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid–Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario by Oriol Calvete, José Reyes, Hernán Valdés-Socin, Paloma Martin, Mónica Marazuela, Alicia Barroso, Javier Escalada, Antoni Castells, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, María Currás-Freixes, Javier Benítez

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Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells by Paolo Petazzi, Raul Torres-Ruiz, Antonella Fidanza, Heleia Roca-Ho, Francisco Gutierrez-Agüera, Julio Castaño, Sandra Rodriguez-Perales, Rafael Díaz de la Guardia, Belén López-Millán, Anna Bigas, Lesley M. Forrester, Clara Bueno, Pablo Menéndez

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Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress by Beatriz Martín-Adrados, Stefanie K. Wculek, Sergio Fernández-Bravo, Raúl Torres-Ruiz, Raúl Torres-Ruiz, Ana Valle-Noguera, Maria José Gomez-Sánchez, José Carlos Hernández-Walias, Frederico Moraes Ferreira, Ana María Corraliza, David Sancho, Vanesa Esteban, Sandra Rodriguez-Perales, Aránzazu Cruz-Adalia, Helder I. Nakaya, Azucena Salas, David Bernardo, David Bernardo, David Bernardo, Yolanda Campos-Martín, Elena Martínez-Zamorano, Diego Muñoz-López, Manuel Gómez del Moral, Francisco Javier Cubero, Francisco Javier Cubero, Richard S. Blumberg, Eduardo Martínez-Naves

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Human T-cell receptor triggering requires inactivation of Lim kinase-1 by Slingshot-1 phosphatase by Álvaro Gómez-Morón, Sergio Alegre-Gómez, Rocio Ramirez-Muñoz, Alicia Hernaiz-Esteban, Carlos Carrasco-Padilla, Camila Scagnetti, Óscar Aguilar-Sopeña, Marta García-Gil, Aldo Borroto, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Francisco Sánchez-Madrid, Noa Beatriz Martín-Cófreces, Pedro Roda-Navarro

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Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions by Clara Bueno, Fernando J Calero-Nieto, Xiaonan Wang, Rafael Valdés-Mas, Francisco Gutiérrez-Agüera, Heleia Roca-Ho, Veronica Ayllon, Pedro J Real, David Arambilet, Lluis Espinosa, Raul Torres-Ruiz, Antonio Agraz-Doblas, Ignacio Varela, Jasper de Boer, Anna Bigas, Bertie Gottgens, Rolf Marschalek, Pablo Menendez

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Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity by Ana García García, María Ferrer Aporta, Germán Vallejo Palma, Antonio Giráldez Trujillo, Raquel Castillo-González, David Calzón Lozano, Alberto Mora Perdiguero, Raúl Muñoz Velasco, Miguel Colina Castro, Elena de Simone Benito, Raúl Torres-Ruiz, Sandra Rodriguez-Perales, Jonas Dehairs, Johannes V. Swinnen, Juan Carlos Garcia-Cañaveras, Agustín Lahoz, Sandra Montalvo Quirós, Carlos del Pozo-Rojas, Clara Luque Rioja, Francisco Monroy, Diego Herráez-Aguilar, Marina Alonso Riaño, José Luis Rodríguez Peralto, Víctor Javier Sánchez-Arévalo Lobo

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Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis by Kang Zheng, Fengjie Hao, Sandra Medrano-Garcia, Chaobo Chen, Feifei Guo, Laura Morán-Blanco, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, María Isabel Peligros, Javier Vaquero, Rafael Bañares, Manuel Gómez del Moral, José R. Regueiro, Eduardo Martínez-Naves, Mohamed Ramadan Mohamed, Rocío Gallego-Durán, Douglas Maya, Javier Ampuero, Manuel Romero-Gómez, Albert Gilbert-Ramos, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho, Mar Coll, Isabel Graupera, Pere Ginès, Andreea Ciudin, Jesús Rivera-Esteban, Juan M. Pericàs, María Dolores Frutos, Bruno Ramos Molina, José María Herranz, Matías A. Ávila, Yulia A. Nevzorova, Edgar Fernández-Malavé, Francisco Javier Cubero

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A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis by Lucía Zhu, Diana Retana, Pedro García‐Gómez, Laura Álvaro‐Espinosa, Neibla Priego, Mariam Masmudi‐Martín, Natalia Yebra, Lauritz Miarka, Elena Hernández‐Encinas, Carmen Blanco‐Aparicio, Sonia Martínez, Cecilia Sobrino, Nuria Ajenjo, Maria‐Jesus Artiga, Eva Ortega‐Paino, Raúl Torres‐Ruiz, Sandra Rodríguez‐Perales, RENACER, Riccardo Soffietti, Luca Bertero, Paola Cassoni, Tobias Weiss, Javier Muñoz, Juan Manuel Sepúlveda, Pedro González‐León, Luis Jiménez‐Roldán, Luis Miguel Moreno, Olga Esteban, Ángel Pérez‐Núñez, Aurelio Hernández‐Laín, Oscar Toldos, Yolanda Ruano, Lucía Alcázar, Guillermo Blasco, José Fernández‐Alén, Eduardo Caleiras, Miguel Lafarga, Diego Megías, Osvaldo Graña‐Castro, Carolina Nör, Michael D Taylor, Leonie S Young, Damir Varešlija, Nicola Cosgrove, Fergus J Couch, Lorena Cussó, Manuel Desco, Silvana Mouron, Miguel Quintela‐Fandino, Michael Weller, Joaquín Pastor, Manuel Valiente, Adolfo de la Lama‐Zaragoza, Lourdes Calero‐Felix, Concepcion Fiaño‐Valverde, Pedro David Delgado‐López, Antonio Montalvo‐Afonso, Mar Pascual‐Llorente, Ángela Díaz‐Piqueras, SH Nam‐Cha, Cristina Barrena López, Gerard Plans Ahicart, Elena Martínez‐Saez, Santiago Ramón y Cajal, Pilar Nicolás

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