Target the Host, Kill the Bug; Targeting Host Respiratory Immunosuppressive Responses as a Novel Strategy to Improve Bacterial Clearance During Lung Infection by Alanna M. Kelly, Rachel M. McLoughlin

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The zwitterionic cell wall teichoic acid of Staphylococcus aureus provokes skin abscesses in mice by a novel CD4+ T-cell-dependent mechanism. by Christopher Weidenmaier, Rachel M McLoughlin, Jean C Lee

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The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens by Keenan A. Lacey, Joan A. Geoghegan, Rachel M. McLoughlin

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Making the Most of the Host; Targeting the Autophagy Pathway Facilitates Staphylococcus aureus Intracellular Survival in Neutrophils by Emilio G. Vozza, Michelle E. Mulcahy, Rachel M. McLoughlin

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Bacterial toxins: Offensive, defensive, or something else altogether? by Justine K Rudkin, Rachel M McLoughlin, Andrew Preston, Ruth C Massey

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Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation. by Alanna M Kelly, John M Leech, Sarah L Doyle, Rachel M McLoughlin

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Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target. by Keenan A Lacey, Michelle E Mulcahy, Aisling M Towell, Joan A Geoghegan, Rachel M McLoughlin

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Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies by Jonah Clegg, Jonah Clegg, Elisabetta Soldaini, Rachel M. McLoughlin, Stephen Rittenhouse, Fabio Bagnoli, Sanjay Phogat

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Human MAIT Cells Respond to <i>Staphylococcus aureus</i> with Enhanced Anti-Bacterial Activity by Andrew J. R. Cooper, Jonah Clegg, Féaron C. Cassidy, Andrew E. Hogan, Rachel M. McLoughlin

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Staphylococcus aureus suppresses the pentose phosphate pathway in human neutrophils via the adenosine receptor A2aR to enhance intracellular survival by Emilio G. Vozza, Clíodhna M. Daly, Sinead A. O'Rourke, Hannah K. Fitzgerald, Aisling Dunne, Rachel M. McLoughlin

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Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils by Michelle E. Mulcahy, Eóin C. O’Brien, Kate M. O’Keeffe, Emilio G. Vozza, Neal Leddy, Rachel M. McLoughlin

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Nasal colonisation by Staphylococcus aureus depends upon clumping factor B binding to the squamous epithelial cell envelope protein loricrin. by Michelle E Mulcahy, Joan A Geoghegan, Ian R Monk, Kate M O'Keeffe, Evelyn J Walsh, Timothy J Foster, Rachel M McLoughlin

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VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity by Josie Ward, Suisheng Zhang, Adam Sikora, Radoslaw Michalski, Yuting Yin, Aurora D'Alessio, Rachel M. McLoughlin, Vincent Jaquet, Franck Fieschi, Ulla G. Knaus

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Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine. by Pádraig J Ross, Caroline E Sutton, Sarah Higgins, Aideen C Allen, Kevin Walsh, Alicja Misiak, Ed C Lavelle, Rachel M McLoughlin, Kingston H G Mills

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Extensive remodelling of the cell wall during the development of Staphylococcus aureus bacteraemia by Edward JA Douglas, Nathanael Palk, Tarcisio Brignoli, Dina Altwiley, Marcia Boura, Maisem Laabei, Mario Recker, Gordon YC Cheung, Ryan Liu, Roger C Hsieh, Michael Otto, Eoin O'Brien, Rachel M McLoughlin, Ruth C Massey

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PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection by Marcin Baran, Claudia Feriotti, Aoife McGinley, Simon R. Carlile, Zhaozhao Jiang, Ricardo Calderon-Gonzalez, Amy Dumigan, Joana Sá-Pessoa, Caroline E. Sutton, Jay Kearney, Rachel M. McLoughlin, Kingston H.G. Mills, Katherine A. Fitzgerald, Jose A. Bengeochea, Andrew G. Bowie

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Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. by Edel A McNeela, Aine Burke, Daniel R Neill, Cathy Baxter, Vitor E Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M McLoughlin, Andres Mori, Barry Moran, Katherine A Fitzgerald, Jurg Tschopp, Virginie Pétrilli, Peter W Andrew, Aras Kadioglu, Ed C Lavelle

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Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection. by Aisling F Brown, Alison G Murphy, Stephen J Lalor, John M Leech, Kate M O'Keeffe, Micheál Mac Aogáin, Dara P O'Halloran, Keenan A Lacey, Mehri Tavakol, Claire H Hearnden, Deirdre Fitzgerald-Hughes, Hilary Humphreys, Jérôme P Fennell, Willem J van Wamel, Timothy J Foster, Joan A Geoghegan, Ed C Lavelle, Thomas R Rogers, Rachel M McLoughlin

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Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression by Liam Townsend, Adam H. Dyer, Aifric Naughton, Sultan Imangaliyev, Jean Dunne, Rachel Kiersey, Dean Holden, Aoife Mooney, Deirdre Leavy, Katie Ridge, Jamie Sugrue, Mubarak Aldoseri, Jo Hannah Kelliher, Martina Hennessy, Declan Byrne, Paul Browne, Christopher L. Bacon, Catriona Doyle, Ruth O’Riordan, Anne-Marie McLaughlin, Ciaran Bannan, Ignacio Martin-Loeches, Arthur White, Rachel M. McLoughlin, Colm Bergin, Nollaig M. Bourke, Cliona O’Farrelly, Niall Conlon, Clíona Ní Cheallaigh

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Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon by Tristram A. J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhan Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke A. J. O’Neill

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