Rafael de Cabo

Rafael de Cabo is a Spanish scientist and Branch Chief of the Translational Gerontology Branch at the National Institute on Aging, a division of the U.S. National Institutes of Health. His research on calorie restriction in rhesus macaques suggested that calorie restriction in monkeys have no significant effects on their lifespan. In 2011, his research on obese mice suggested that resveratrol mimetic helps extend longevity and his research on male mice suggested that metformin have a longevity effect. Provided by Wikipedia
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  1. 1
    Short-term senolytic treatment: a paradigm to promote fracture repair during aging

    Short-term senolytic treatment: a paradigm to promote fracture repair during aging by Isabel Beerman, Nathan Basisty, Rafael de Cabo

    Published 2022-04-01
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  2. 2
    Frontiers in aging special issue: DNA repair and interventions in aging perspective on “loss of epigenetic information as a cause of mammalian aging”

    Frontiers in aging special issue: DNA repair and interventions in aging perspective on “loss of epigenetic information as a cause of mammalian aging” by Ethan D. Schaffer, Isabel Beerman, Rafael de Cabo, Robert M. Brosh

    Published 2023-07-01
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  3. 3
    Amniotic epithelial cells: a new tool to combat aging and age-related diseases?

    Amniotic epithelial cells: a new tool to combat aging and age-related diseases? by Clara Di Germanio, Clara Di Germanio, Michel Bernier, Rafael de Cabo, Barbara Barboni

    Published 2016-11-01
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  4. 4
    Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation.

    Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation. by Hitoshi Watanabe, Shun-Ichiro Asahara, Jinsook Son, Wendy M McKimpson, Rafael de Cabo, Domenico Accili

    Published 2024-01-01
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  5. 5
    JNK1 phosphorylates SIRT1 and promotes its enzymatic activity.

    JNK1 phosphorylates SIRT1 and promotes its enzymatic activity. by Nargis Nasrin, Virendar K Kaushik, Eric Fortier, Daniel Wall, Kevin J Pearson, Rafael de Cabo, Laura Bordone

    Published 2009-12-01
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  6. 6
    Redox state and the sirtuin deacetylases are major factors that regulate the acetylation status of the stress protein NQO1

    Redox state and the sirtuin deacetylases are major factors that regulate the acetylation status of the stress protein NQO1 by David Siegel, Peter S. Harris, Cole R. Michel, Cole R. Michel, Rafael de Cabo, Kristofer S. Fritz, David Ross

    Published 2022-11-01
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  7. 7
    RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression

    RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression by Paula Martínez, Gonzalo Gómez-López, Fernando García, Evi Mercken, Sarah Mitchell, Juana M. Flores, Rafael de Cabo, Maria A. Blasco

    Published 2013-07-01
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  8. 8
    RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression

    RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression by Paula Martínez, Gonzalo Gómez-López, Fernando García, Evi Mercken, Sarah Mitchell, Juana M. Flores, Rafael de Cabo, Maria A. Blasco

    Published 2013-06-01
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  9. 9
    In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets.

    In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets. by Joanne S Allard, Leonie K Heilbronn, Carolina Smith, Nicole D Hunt, Donald K Ingram, Eric Ravussin, Pennington CALERIE Team, Rafael de Cabo

    Published 2008-09-01
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  10. 10
    A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation

    A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation by David Siegel, Stephanie Bersie, Peter Harris, Andrea Di Francesco, Michael Armstrong, Nichole Reisdorph, Michel Bernier, Rafael de Cabo, Kristofer Fritz, David Ross

    Published 2021-02-01
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  11. 11
    Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis.

    Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis. by Hannes M Findeisen, Kevin J Pearson, Florence Gizard, Yue Zhao, Hua Qing, Karrie L Jones, Dianne Cohn, Elizabeth B Heywood, Rafael de Cabo, Dennis Bruemmer

    Published 2011-04-01
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  12. 12
    microRNA-33 controls hunger signaling in hypothalamic AgRP neurons

    microRNA-33 controls hunger signaling in hypothalamic AgRP neurons by Nathan L. Price, Pablo Fernández-Tussy, Luis Varela, Magdalena P. Cardelo, Marya Shanabrough, Binod Aryal, Rafael de Cabo, Yajaira Suárez, Tamas L. Horvath, Carlos Fernández-Hernando

    Published 2024-03-01
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  13. 13
    Caloric restriction improves health and survival of rhesus monkeys

    Caloric restriction improves health and survival of rhesus monkeys by Julie A. Mattison, Ricki J. Colman, T. Mark Beasley, David B. Allison, Joseph W. Kemnitz, George S. Roth, Donald K. Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M. Anderson

    Published 2017-01-01
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  14. 14
    Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates.

    Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates. by Mereena George Ushakumary, Mingyi Wang, Harikrishnan V, Allen Sam Titus, Jing Zhang, Lijuan Liu, Robert Monticone, Yushi Wang, Julie A Mattison, Rafael de Cabo, Edward G Lakatta, Shivakumar Kailasam

    Published 2019-01-01
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  15. 15
    The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

    The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. by Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair

    Published 2008-04-01
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  16. 16
    A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin

    A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin by Morgan Levine, Ross A McDevitt, Margarita Meer, Kathy Perdue, Andrea Di Francesco, Theresa Meade, Colin Farrell, Kyra Thrush, Meng Wang, Christopher Dunn, Matteo Pellegrini, Rafael de Cabo, Luigi Ferrucci

    Published 2020-11-01
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  17. 17
    Calorie Restriction Curbs Proinflammation That Accompanies Arterial Aging, Preserving a Youthful Phenotype

    Calorie Restriction Curbs Proinflammation That Accompanies Arterial Aging, Preserving a Youthful Phenotype by Mingyi Wang, Li Zhang, Wanqu Zhu, Jing Zhang, Soo Hyuk Kim, Yushi Wang, Leng Ni, Richard Telljohann, Robert E. Monticone, Kimberly McGraw, Lijuan Liu, Rafael de Cabo, Edward G. Lakatta

    Published 2018-09-01
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  18. 18
    Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

    Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice by Samantha M. Solon-Biet, Sarah J. Mitchell, Sean C.P. Coogan, Victoria C. Cogger, Rahul Gokarn, Aisling C. McMahon, David Raubenheimer, Rafael de Cabo, Stephen J. Simpson, David G. Le Couteur

    Published 2015-06-01
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  19. 19
    Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.

    Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males. by Bronwen Martin, Michele Pearson, Randall Brenneman, Erin Golden, Alex Keselman, Titilola Iyun, Olga D Carlson, Josephine M Egan, Kevin G Becker, William Wood, Vinayakumar Prabhu, Rafael de Cabo, Stuart Maudsley, Mark P Mattson

    Published 2008-06-01
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  20. 20
    Health benefits of late-onset metformin treatment every other week in mice

    Health benefits of late-onset metformin treatment every other week in mice by Irene Alfaras, Sarah J. Mitchell, Hector Mora, Darisbeth Rosario Lugo, Alessandra Warren, Ignacio Navas-Enamorado, Vickie Hoffmann, Christopher Hine, James R. Mitchell, David G. Le Couteur, Victoria C. Cogger, Michel Bernier, Rafael de Cabo

    Published 2017-11-01
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