Functional analysis of GCKR mutations identified in subjects with hypertriglyceridaemia demonstrates the inherent challenges in clinical interpretation of rare variants by Raimondo, A, Rees, MG, Wang, J, Barrett, A, Collins, F, Hegele, R, Gloyn, A

Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence. by Zelent, B, Raimondo, A, Barrett, A, Buettger, C, Chen, P, Gloyn, A, Matschinsky, F

Reclassification of diabetes aetiology in a family with multiple diabetes phenotypes by Kavvoura, F, Raimondo, A, Thanabalasingham, G, Barrett, A, Webster, A, Mann, N, Ellard, S, Gloyn, A, Owen, K

A panel of diverse assays to interrogate the interaction between glucokinase and glucokinase regulatory protein, two vital proteins in human disease by Rees, MG, Davis, M, Shen, M, Titus, S, Raimondo, A, Barrett, A, Gloyn, A, Collins, F, Simeonov, A

Reclassification of diabetes etiology in a family with multiple diabetes phenotypes. by Kavvoura, F, Raimondo, A, Thanabalasingham, G, Barrett, A, Webster, A, Shears, D, Mann, N, Ellard, S, Gloyn, A, Owen, K

The phenotypic severity of homozygous GCK mutations causing neonatal or adolescent-onset diabetes is mediated through thermostability in addition to enzyme activity by Chakera, A, Raimondo, A, Homsen, S, Colclough, K, Barrett, A, De-Franco, E, Chatelas, A, van de Bunt, M, Flanagan, SE, Hattersley, A, Ellard, S, Gloyn, A

Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families. by Rees, MG, Raimondo, A, Wang, J, Ban, MR, Davis, M, Barrett, A, Ranft, J, Jagdhuhn, D, Waterstradt, R, Baltrusch, S, Simeonov, A, Collins, F, Hegele, R, Gloyn, A

Phenotypic severity of homozygous GCK mutations causing neonatal or childhood-onset diabetes is primarily mediated through effects on protein stability. by Raimondo, A, Chakera, A, Thomsen, S, Colclough, K, Barrett, A, De Franco, E, Chatelas, A, Demirbilek, H, Akcay, T, Alawneh, H, Flanagan, SE, Van De Bunt, M, Hattersley, A, Gloyn, A, Ellard, S

Insights into the pathogenicity of rare missense GCK variants from the identification and functional characterization of compound heterozygous and double mutations inherited in cis... by Beer, N, Osbak, K, van de Bunt, M, Tribble, N, Steele, A, Wensley, K, Edghill, E, Colcough, K, Barrett, A, Valentínová, L, Rundle, J, Raimondo, A, Grimsby, J, Ellard, S, Gloyn, A

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic beta cells by Thomsen, S, Raimondo, A, Hastoy, B, Sengupta, S, Dai, X, Bautista, A, Censin, J, Payne, A, Umapathysivam, M, Spigelman, A, Barrett, A, Groves, C, Beer, N, Manning Fox, J, McCarthy, M, Clark, A, Mahajan, A, Rorsman, O, MacDonald, P, Gloyn, A

Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci by Gaulton, KJ, Ferreira, T, Lee, Y, Raimondo, A, Mägi, R, Mahajan, A, Rayner, N, Morris, A, Thomsen, S, van de Bunt, M, Beer, N, Gloyn, A, Lindgren, C, Robertson, N, Trakalo, J, Wiltshire, S, Ingelsson, E, Donnelly, P, Rundle, J, Groves, C, Owen, K, Reschen, M, Chalisey, A, O'Callaghan, C, McCarthy, M, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM)