PB1788: A SCREENING OF DONATED CHEMICAL PROBES TO IDENTIFY NOVEL THERAPEUTIC OPTIONS FOR ACUTE MYELOID LEUKEMIA (AML) IN CHILDHOOD by Stephanie Laszig, Raj Bhayadia, Jan-Henning Klusmann, Stefan Knapp

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P419: HARNESSING MIRNA-193B-3P MIMIC AS A POTENT THERAPEUTIC OPTION IN ACUTE MYELOID LEUKEMIA by Hasan Issa, Raj Bhayadia, Robert Winkler, Dirk Heckl, Jan-Henning Klusmann

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P467: LONG NON-CODING RNA SNHG29 IS A NOVEL MYELOID LEUKEMIA DEPENDENCY by Robert Winkler, Dirk Heckl, Michelle Ng, Reinier Boon, Hasan Issa, Raj Bhayadia, Jan-Henning Klusmann

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PB1825: IDENTIFYING GENE TARGETS FOR DRUG REPURPOSING TO COUNTER MYELOID LEUKEMIA IN CHILDREN WITH DOWN-SYNDROME (ML-DS) by Anna-Lena Schmell, Kristof Meier, Oriol Alejo-Valle, Dirk Heckel, Raj Bhayadia, Jan-Henning Klusmann

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GATA1s exerts developmental stage-specific effects in human hematopoiesis by Sofia Gialesaki, Anna Katharina Mahnken, Lena Schmid, Maurice Labuhn, Raj Bhayadia, Dirk Heckl, Jan-Henning Klusmann

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The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia by Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann

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Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15 by Michelle Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Marit Willemijn Vermunt, Robert Winkler, Leah Schüler, Oriol Alejo, Konstantin Schuschel, Eniko Regenyi, Dorit Borchert, Michael Heuser, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann

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P1354: CRISPR/CAS9 GENE EDITING OF IMMUNE CHECKPOINT RECEPTOR NKG2A IMPROVES THE ANTI-LEUKEMIC EFFICACY OF PRIMARY CD33-TARGETING CAR-NK CELLS. by Nawid Albinger, Tobias Bexte, Ahmad Al-Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz Särchen, Meike Vogler, Raj Bhayadia, Jan-Henning Klusmann, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich

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CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells by Tobias Bexte, Nawid Albinger, Ahmad Al Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz Särchen, Meike Vogler, Hadeer Mohamed Rasheed, Beate Anahita Jung, Sebastian Wolf, Raj Bhayadia, Thomas Oellerich, Jan-Henning Klusmann, Olaf Penack, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich

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P422: TARGETING THE WT1MUT-MIR-193A TRANSCRIPTIONAL AXIS WITH INT-1B3, A NOVEL LIPID NANOPARTICLE-FORMULATED MIR-193A-3P MIMIC IN ACUTE MYELOID LEUKEMIA by Xining Yang, Kathrin Krowiorz, Daelynn Buelow, Raj Bhayadia, Jessica Kohlschmidt, Deedra Nicolet, Tobias Maetzig, Caroline Pabst, Jeremy Hui, Arshia Shad, Sharon Gao, Maria Stephenson, Si Wei Wu, Marion van den Bosch, Leo Escano, Frances Lock, Afsaneh Panahi, Liam Macphee, Irina Maksakova, Amanda Amoah, Konstanze Döhner, Linda Fogelstrand, Ann-Kathrin Eisfeld, Sanaz Yahyanejad, Michel Janicot, Jan-Henning Klusmann, Sharyn Baker, Christopher Oakes, Arefeh Rouhi, Florian Kuchenbauer

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