Ralph DeBerardinis

Ralph J. DeBerardinis is an American physician-scientist, the chief of the Division of Pediatric Genetics and Metabolism at the Children’s Medical Center Research Institute at UT Southwestern and a professor at the University of Texas Southwestern Medical Center. DeBerardinis became a Howard Hughes Medical Institute Investigator in 2018. DeBerardinis was elected to the National Academy of Medicine in 2020. DeBerardinis is known for his contributions to research on cancer and pediatric inborn errors of metabolism. Provided by Wikipedia
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  1. 1
    Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity

    Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity by Ling Cai, Ralph J. DeBerardinis, Guanghua Xiao, John D. Minna, Yang Xie

    Published 2023-06-01
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  2. 2
    Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy

    Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy by Stefan Stender, Vlad G. Zaha, Craig R. Malloy, Jessica Sudderth, Ralph J. DeBerardinis, Jae Mo Park

    Published 2020-03-01
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  3. 3
    Partial N‐acetyl glutamate synthase deficiency presenting as postpartum hyperammonemia: Diagnosis and subsequent pregnancy management

    Partial N‐acetyl glutamate synthase deficiency presenting as postpartum hyperammonemia: Diagnosis and subsequent pregnancy management by Lea Abou Haidar, Panayotis Pachnis, Garrett K. Gotway, Min Ni, Ralph J. DeBerardinis, Markey C. McNutt

    Published 2023-11-01
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  4. 4
    IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells

    IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells by Afshan Fathima Nawas, Ashley Solmonson, Boning Gao, Ralph J. DeBerardinis, John D. Minna, Maralice Conacci-Sorrell, Carole R. Mendelson

    Published 2023-11-01
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  5. 5
    Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities

    Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities by Jermaine Goveia, Andreas Pircher, Lena‐Christin Conradi, Joanna Kalucka, Vincenzo Lagani, Mieke Dewerchin, Guy Eelen, Ralph J DeBerardinis, Ian D Wilson, Peter Carmeliet

    Published 2016-09-01
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  6. 6
    A review of multiple diagnostic approaches in the undiagnosed diseases network to identify inherited metabolic diseases

    A review of multiple diagnostic approaches in the undiagnosed diseases network to identify inherited metabolic diseases by Yutaka Furuta, Rory J. Tinker, Rizwan Hamid, Joy D. Cogan, Kimberly M. Ezell, Devin Oglesbee, Ralph J. DeBerardinis, John A. Phillips, the Undiagnosed Diseases Network

    Published 2024-11-01
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  7. 7
    Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation

    Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation by Yi-Heng Hao, M. Carmen Lafita-Navarro, Lauren Zacharias, Nofit Borenstein-Auerbach, Min Kim, Spencer Barnes, Jiwoong Kim, Jerry Shay, Ralph J. DeBerardinis, Maralice Conacci-Sorrell

    Published 2019-10-01
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  8. 8
    Targeting acetylcholine signaling modulates persistent drug tolerance in EGFR-mutant lung cancer and impedes tumor relapse

    Targeting acetylcholine signaling modulates persistent drug tolerance in EGFR-mutant lung cancer and impedes tumor relapse by Meng Nie, Na Chen, Huanhuan Pang, Tao Jiang, Wei Jiang, Panwen Tian, LiAng Yao, Yangzi Chen, Ralph J. DeBerardinis, Weimin Li, Qitao Yu, Caicun Zhou, Zeping Hu

    Published 2022-10-01
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  9. 9
    MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies

    MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies by GuemHee Baek, Yan F. Tse, Zeping Hu, Derek Cox, Noah Buboltz, Peter McCue, Charles J. Yeo, Michael A. White, Ralph J. DeBerardinis, Erik S. Knudsen, Agnieszka K. Witkiewicz

    Published 2014-12-01
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  10. 10
    Differential requirements for mitochondrial electron transport chain components in the adult murine liver

    Differential requirements for mitochondrial electron transport chain components in the adult murine liver by Nicholas P Lesner, Xun Wang, Zhenkang Chen, Anderson Frank, Cameron J Menezes, Sara House, Spencer D Shelton, Andrew Lemoff, David G McFadden, Janaka Wansapura, Ralph J DeBerardinis, Prashant Mishra

    Published 2022-09-01
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  11. 11
    New insights in the targets of action of dimethyl fumarate in endothelial cells: effects on energetic metabolism and serine synthesis in vitro and in vivo

    New insights in the targets of action of dimethyl fumarate in endothelial cells: effects on energetic metabolism and serine synthesis in vitro and in vivo by Mª Carmen Ocaña, Manuel Bernal, Chendong Yang, Carlos Caro, Alejandro Domínguez, Hieu S. Vu, Casimiro Cárdenas, María Luisa García-Martín, Ralph J. DeBerardinis, Ana R. Quesada, Beatriz Martínez-Poveda, Miguel Ángel Medina

    Published 2023-10-01
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  12. 12
    Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency

    Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency by Bryn D Webb, Sara M Nowinski, Ashley Solmonson, Jaya Ganesh, Richard J Rodenburg, Joao Leandro, Anthony Evans, Hieu S Vu, Thomas P Naidich, Bruce D Gelb, Ralph J DeBerardinis, Jared Rutter, Sander M Houten

    Published 2023-03-01
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  13. 13
    Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

    Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research by John Kurhanewicz, Daniel B. Vigneron, Kevin Brindle, Eduard Y. Chekmenev, Arnaud Comment, Charles H. Cunningham, Ralph J. DeBerardinis, Gary G. Green, Martin O. Leach, Sunder S. Rajan, Rahim R. Rizi, Brian D. Ross, Warren S. Warren, Craig R. Malloy

    Published 2011-02-01
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  14. 14
    BBOX1 restrains TBK1-mTORC1 oncogenic signaling in clear cell renal cell carcinoma

    BBOX1 restrains TBK1-mTORC1 oncogenic signaling in clear cell renal cell carcinoma by Chengheng Liao, Lianxin Hu, Liwei Jia, Jin Zhou, Tao Wang, Kangsan Kim, Hua Zhong, Hongwei Yao, Lei Dong, Lei Guo, Qian Liang, Cheng Zhang, Fangzhou Zhao, Jun Fang, Hongyi Liu, Shina Li, Lin Xu, Jeremy M. Simon, Srinivas Malladi, Payal Kapur, James Brugarolas, Ralph J. DeBerardinis, Qing Zhang

    Published 2025-02-01
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  15. 15
    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria by Sara M Nowinski, Ashley Solmonson, Scott F Rusin, J Alan Maschek, Claire L Bensard, Sarah Fogarty, Mi-Young Jeong, Sandra Lettlova, Jordan A Berg, Jeffrey T Morgan, Yeyun Ouyang, Bradley C Naylor, Joao A Paulo, Katsuhiko Funai, James E Cox, Steven P Gygi, Dennis R Winge, Ralph J DeBerardinis, Jared Rutter

    Published 2020-08-01
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  16. 16
    Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis

    Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis by Niranjan Venkateswaran, Roy Garcia, M. Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A. S. Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A. Kilgore, Shun Fang, Isabella N. Brown, Li Li, Emily Parks, Igor Lopes dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V. Grishin, Lisa Kinch, Lin Xu, Noelle S. Williams, Jerry W. Shay, Ralph J. DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell

    Published 2024-05-01
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  17. 17
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas by Meng-Hsiung Hsieh, Joshua H. Choe, Jashkaran Gadhvi, Yoon Jung Kim, Marcus A. Arguez, Madison Palmer, Haleigh Gerold, Chance Nowak, Hung Do, Simbarashe Mazambani, Jordan K. Knighton, Matthew Cha, Justin Goodwin, Min Kyu Kang, Ji Yun Jeong, Shin Yup Lee, Brandon Faubert, Zhenyu Xuan, E. Dale Abel, Claudio Scafoglio, David B. Shackelford, John D. Minna, Pankaj K. Singh, Vladimir Shulaev, Leonidas Bleris, Kenneth Hoyt, James Kim, Masahiro Inoue, Ralph J. DeBerardinis, Tae Hoon Kim, Jung-whan Kim

    Published 2019-08-01
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