Time to Move to the Single-Cell Level: Applications of Single-Cell Multi-Omics to Hematological Malignancies and Waldenström’s Macroglobulinemia—A Particularly Heterogeneous Lympho... by Ramón García-Sanz, Cristina Jiménez

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Minimal Residual Disease in Multiple Myeloma: Past, Present, and Future by Alejandro Medina-Herrera, María Eugenia Sarasquete, Cristina Jiménez, Noemí Puig, Ramón García-Sanz

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Long-term reversibility of renal dysfunction associated to light chain deposition disease with bortezomib and dexamethasone and high dose therapy and autologous stem cell transplan... by Tomás J. González-López, Lourdes Vázquez, Teresa Flores, Jesus Fernando San Miguel, Ramon García-Sanz

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Genetics of Transformed Follicular Lymphoma by Miguel Alcoceba, María García-Álvarez, Jessica Okosun, Simone Ferrero, Marco Ladetto, Jude Fitzgibbon, Ramón García-Sanz

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Immune System Alterations in Multiple Myeloma: Molecular Mechanisms and Therapeutic Strategies to Reverse Immunosuppression by Andrea Díaz-Tejedor, Mauro Lorenzo-Mohamed, Noemí Puig, Ramón García-Sanz, María-Victoria Mateos, Mercedes Garayoa, Teresa Paíno

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<i>MYD88</i> Mutations: Transforming the Landscape of IgM Monoclonal Gammopathies by Miguel Alcoceba, María García-Álvarez, Alejandro Medina, Rebeca Maldonado, Verónica González-Calle, María Carmen Chillón, María Eugenia Sarasquete, Marcos González, Ramón García-Sanz, Cristina Jiménez

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Multiple myeloma with t(11;14): impact of novel agents on outcome by Borja Puertas, Verónica González-Calle, Eduardo Sobejano-Fuertes, Fernando Escalante, Beatriz Rey-Bua, Irene Padilla, Ramón García-Sanz, Noemi Puig, Norma C. Gutiérrez, María-Victoria Mateos

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RNA sequencing identifies novel regulated IRE1-dependent decay targets that affect multiple myeloma survival and proliferation by Dalia Quwaider, Luis A. Corchete, Marta Martín-Izquierdo, Jesús M. Hernández-Sánchez, Elizabeta A. Rojas, Ignacio J. Cardona-Benavides, Ramón García-Sanz, Ana B. Herrero, Norma C. Gutiérrez

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DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma by Dalia Quwaider, Luis A. Corchete, Irena Misiewicz-Krzeminska, María E. Sarasquete, José J. Pérez, Patryk Krzeminski, Noemí Puig, María Victoria Mateos, Ramón García-Sanz, Ana B. Herrero, Norma C. Gutiérrez

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P1679: HEALTH-RELATED QUALITY OF LIFE IN PATIENTS (PTS) WITH WALDENSTRÖM MACROGLOBULINEMIA (WM) TREATED WITH ZANUBRUTINIB (ZANU) VS IBRUTINIB (IBR): RESULTS FROM THE PHASE 3 ASPEN... by Alessandra Tedeschi, Constantine Tam, Roger Owen, Christian Buske, Véronique Leblond, Meletios A. Dimopoulos, Ramón García-Sanz, Jorge Castillo, Judith Trotman, Steven Treon, Keri Yang, Boxiong Tang, Heather Allewelt, Sheel Patel, Wai Chan, Aileen Cohen, Jingjing Yan Schneider, Gisoo Barnes

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Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design. by Almudena Aguilera-Diaz, Iria Vazquez, Beñat Ariceta, Amagoia Mañú, Zuriñe Blasco-Iturri, Sara Palomino-Echeverría, María José Larrayoz, Ramón García-Sanz, María Isabel Prieto-Conde, María Del Carmen Chillón, Ana Alfonso-Pierola, Felipe Prosper, Marta Fernandez-Mercado, María José Calasanz

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Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma by Esperanza M. Algarín, Dalia Quwaider, Francisco J. Campos-Laborie, Andrea Díaz-Tejedor, Pedro Mogollón, Elena Vuelta, Montserrat Martín-Sánchez, Laura San-Segundo, Lorena González-Méndez, Norma C. Gutiérrez, Ramón García-Sanz, Teresa Paíno, Javier De Las Rivas, Enrique M. Ocio, Mercedes Garayoa

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Differences in the immunoglobulin gene repertoires of IgG versus IgA multiple myeloma allude to distinct immunopathogenetic trajectories by Glykeria Gkoliou, Glykeria Gkoliou, Andreas Agathangelidis, Georgos Karakatsoulis, Georgos Karakatsoulis, Chrysavgi Lalayanni, Apostolia Papalexandri, Alejandro Medina, Elisa Genuardi, Katerina Chlichlia, Evdoxia Hatjiharissi, Maria Papaioannou, Evangelos Terpos, Cristina Jimenez, Ioanna Sakellari, Simone Ferrero, Marco Ladetto, Ramon Garcia Sanz, Chrysoula Belessi, Kostas Stamatopoulos, Kostas Stamatopoulos

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P107: Effect of Brentuximab Vedotin Addition to Chemotherapy and Prognostic Factors in Patients with Relapsed/Refractory Hodgkin Lymphoma: a Large Multi-Trial Analysis Based on Ind... by Julia Driessen, Fer De Wit, Alex F. Herrera, Pier Luigi Zinzani, Ann S. Lacasce, Peter D. Cole, Craig H. Moskowitz, Ramón. García Sanz, Michael Fuchs, Horst Müller, Peter Borchmann, Armando Santoro, Heiko Schöder, Josée. M. Zijlstra, Barbara A. Hutten, Alison J. Moskowitz, Marie José Kersten

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Single-Cell DNA Sequencing and Immunophenotypic Profiling to Track Clonal Evolution in an Acute Myeloid Leukemia Patient by María García-Álvarez, Ana Yeguas, Cristina Jiménez, Alejandro Medina-Herrera, Verónica González-Calle, Montserrat Hernández-Ruano, Rebeca Maldonado, Irene Aires, Cristina Casquero, Inmaculada Sánchez-Villares, Ana Balanzategui, María Eugenia Sarasquete, Miguel Alcoceba, María Belén Vidriales, Marcos González-Díaz, Ramón García-Sanz, María Carmen Chillón

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Clonal architecture and evolutionary history of Waldenström's macroglobulinemia at the single-cell level by Ramón García-Sanz, María García-Álvarez, Alejandro Medina, Elham Askari, Verónica González-Calle, María Casanova, Igor de la Torre-Loizaga, Fernando Escalante-Barrigón, Miguel Bastos-Boente, Abelardo Bárez, Nerea Vidaña-Bedera, José María Alonso, María Eugenia Sarasquete, Marcos González, María Carmen Chillón, Miguel Alcoceba, Cristina Jiménez

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T021: Radiation-Free Therapy as the INitial treatment of Good-prognosis early non-bulky Hodgkin lymphoma, defined by a low Metabolic Tumor Volume and a negative PET-2 - RAFTING Tri... by Andrea Gallamini, Marco Picardi, Kateryna Filonenko, Manuel Gotti, Javier Núñez Céspedes, Andrea Rossi, Eva Domingo-Domènech, Agnieszka Giza, Roberto Sorasio, Livio Trentin, Mariana Bastos Oteiro, Ewa Paszkiewicz-Kozik, Ramon García Sanz, Caterina Patti, Stephane Chauvie, Fabrizio Bergesio, Luca Guerra, Alessandro Rambaldi, Ana Sureda Balari, Jan Maciej Zaucha

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P848: EXPRESSION PROFILE OF BCL-2 FAMILY PROTEINS IN MULTIPLE MYELOMA. by Cristina De Ramón Sánchez, Elizabeta A Rojas, Irena Misiewicz-Krzeminska, Ignacio J Cardona-Benavides, Myriam Cuadrado, Isabel Isidro, Maria Jose Calasanz, Ramón García-Sanz, Laura Rosiñol Dachs, Joaquín Martinez-Lopez, Joan Baldé, Juan J Lahuerta, Jesus F San Miguel, Maria-Victoria Mateos, Luis A Corchete, Norma Carmen Gutierrez Gutierrez

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Novel Agents as Main Drivers for Continued Improvement in Survival in Multiple Myeloma by Borja Puertas, Verónica González-Calle, Eduardo Sobejano-Fuertes, Fernando Escalante, José A. Queizán, Abelardo Bárez, Jorge Labrador, José María Alonso-Alonso, Alfonso García de Coca, Alberto Cantalapiedra, Teresa Villaescusa, Carlos Aguilar-Franco, Elena Alejo-Alonso, Beatriz Rey-Bua, Lucía López-Corral, Ramón García-Sanz, Noemi Puig, Norma C. Gutiérrez, María-Victoria Mateos

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HLA specificities are associated with prognosis in IGHV-mutated CLL-like high-count monoclonal B cell lymphocytosis. by María García-Álvarez, Miguel Alcoceba, Miriam López-Parra, Noemí Puig, Alicia Antón, Ana Balanzategui, Isabel Prieto-Conde, Cristina Jiménez, María E Sarasquete, M Carmen Chillón, María Laura Gutiérrez, Rocío Corral, José María Alonso, José Antonio Queizán, Julia Vidán, Emilia Pardal, María Jesús Peñarrubia, José M Bastida, Ramón García-Sanz, Luis Marín, Marcos González

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