Proapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesis by Florita C. Henderson, Olga L. Miakotina, Rama K. Mallampalli

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Upregulation of surfactant synthesis triggers ABCA1-mediated basolateral phospholipid efflux by Jiming Zhou, Yong You, Alan J. Ryan, Rama K. Mallampalli

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LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia by Zhiwei Xu, Jiming Zhou, Diann M. McCoy, Rama K. Mallampalli

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Lipoprotein deprivation stimulates transcription of the CTP:phosphocholine cytidylyltransferase gene by Alan J. Ryan, Diann M. McCoy, Satya N. Mathur, F. Jeffrey Field, Rama K. Mallampalli

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Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation by Elizabeth A. Lendermon, Tiffany A. Coon, Joseph S. Bednash, Nathaniel M. Weathington, John F. McDyer, Rama K. Mallampalli

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The deubiquitinase USP13 stabilizes the anti-inflammatory receptor IL-1R8/Sigirr to suppress lung inflammationResearch in context by Lian Li, Jianxin Wei, Shuang Li, Anastasia M. Jacko, Nathaniel M. Weathington, Rama K. Mallampalli, Jing Zhao, Yutong Zhao

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FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells by Tomeka L. Suber, Ina Nikolli, Michael E. O’Brien, James Londino, Jing Zhao, Kong Chen, Rama K. Mallampalli, Yutong Zhao

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The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β by Jiaxing Miao, Lian Li, Nargis Shaheen, Jianxin Wei, Anastasia M. Jacko, Prithu Sundd, Sarah J. Taleb, Rama K. Mallampalli, Yutong Zhao, Jing Zhao

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Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity by Joseph S. Bednash, Nathaniel Weathington, James Londino, Mauricio Rojas, Dexter L. Gulick, Robert Fort, SeungHye Han, Alison C. McKelvey, Bill B. Chen, Rama K. Mallampalli

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RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia by Hannah Voic, Xiuying Li, Jun-Ho Jang, Chunbin Zou, Prithu Sundd, Jonathan Alder, Mauricio Rojas, Divay Chandra, Scott Randell, Rama K. Mallampalli, Yohannes Tesfaigzi, Tyrone Ryba, Toru Nyunoya

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Factor H preserves alternative complement function during ARDS, linked to improved survival by William Bain, Mohammadreza Tabary, Sara R. Moore, Xiaojing An, Georgios D. Kitsios, Bryan J. McVerry, Prabir Ray, Anuradha Ray, Rama K. Mallampalli, Viviana P. Ferreira, Janet S. Lee, S. Mehdi Nouraie

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Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia by Yandong Lai, Xiuying Li, Tiao Li, Toru Nyunoya, Kong Chen, Georgios D. Kitsios, Seyed Mehdi Nouraie, Yingze Zhang, Bryan J. McVerry, Janet S. Lee, Rama K. Mallampalli, Chunbin Zou

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Longitudinal transcriptomic analysis reveals persistent enrichment of iron homeostasis and erythrocyte function pathways in severe COVID-19 ARDS by Moemen Eltobgy, Finny Johns, Daniela Farkas, Laura Leuenberger, Sarah P. Cohen, Kevin Ho, Sarah Karow, Gabrielle Swoope, Sonal Pannu, Jeffrey C. Horowitz, Rama K. Mallampalli, Joshua A. Englert, Joseph S. Bednash, Joseph S. Bednash

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Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors by Cong Zeng, John P. Evans, Rebecca Pearson, Panke Qu, Yi-Min Zheng, Richard T. Robinson, Luanne Hall-Stoodley, Jacob Yount, Sonal Pannu, Rama K. Mallampalli, Linda Saif, Eugene Oltz, Gerard Lozanski, Shan-Lu Liu

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A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO• sabotage of theft-ferroptosis by Haider H. Dar, Tamil S. Anthonymuthu, Liubov A. Ponomareva, Austin B. Souryavong, Galina V. Shurin, Alexandr O. Kapralov, Vladimir A. Tyurin, Janet S. Lee, Rama K. Mallampalli, Sally E. Wenzel, Hülya Bayir, Valerian E. Kagan

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Interferon Lambda Signaling in Macrophages Is Necessary for the Antiviral Response to Influenza by Rama K. Mallampalli, Jessica Adair, Ajit Elhance, Daniela Farkas, Lexie Chafin, Matthew E. Long, Matthew E. Long, Mithu De, Ana L. Mora, Mauricio Rojas, Victor Peters, Joseph S. Bednash, MuChun Tsai, James D. Londino

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Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome by Tomeka L. Suber, Stacy G. Wendell, Steven J. Mullett, Benjamin Zuchelkowski, William Bain, Georgios D. Kitsios, Bryan J. McVerry, Prabir Ray, Anuradha Ray, Rama K. Mallampalli, Yingze Zhang, Faraaz Shah, Seyed Mehdi Nouraie, Janet S. Lee

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The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia by Krishnendu Chakraborty, Mahesh Raundhal, Bill B. Chen, Christina Morse, Yulia Y. Tyurina, Anupriya Khare, Timothy B. Oriss, Rachael Huff, Janet S. Lee, Claudette M. St. Croix, Simon Watkins, Rama K. Mallampalli, Valerian E. Kagan, Anuradha Ray, Prabir Ray

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Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure by Sudipta Das, Tomasz W. Kaminski, Brent T. Schlegel, William Bain, Sanmei Hu, Akruti Patel, Sagar L. Kale, Kong Chen, Janet S. Lee, Rama K. Mallampalli, Valerian E. Kagan, Dhivyaa Rajasundaram, Bryan J. McVerry, Prithu Sundd, Georgios D. Kitsios, Anuradha Ray, Prabir Ray

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Distinct patterns of SARS-CoV-2 BA.2.87.1 and JN.1 variants in immune evasion, antigenicity, and cell-cell fusion by Pei Li, Yajie Liu, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yi-Min Zheng, Claire Carlin, Joseph S. Bednash, Jeffrey C. Horowitz, Rama K. Mallampalli, Linda J. Saif, Eugene M. Oltz, Daniel Jones, Jianrong Li, Richard J. Gumina, Shan-Lu Liu

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