Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models by Nupur Chaphekar, Prerna Dodeja, Imam H. Shaik, Steve Caritis, Raman Venkataramanan, Raman Venkataramanan, Raman Venkataramanan

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348 Translating a precision dosing approach for opioid use disorder in Puerto Rico: Pilot testing of the clinical utility and patient/provider acceptability by Darlene Santiago, Jorge Duconge, Raman Venkataramanan, Francisco Gonzalez

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Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes by Roberto Gramignoli, Aarati R. Ranade, Raman Venkataramanan, Stephen C. Strom

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A systematic review of pregnancy-related clinical intervention of drug regimens due to pharmacokinetic reasons by Lauren A. Borda, Mats Någård, David W. Boulton, Raman Venkataramanan, Paola Coppola

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Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico by Darlene Santiago, Victor Mangas-Sanjuan, Kyle Melin, Jorge Duconge, Wenchen Zhao, Raman Venkataramanan

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Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokine... by Firuz G. Feturi, Matthias Weinstock, Wenchen Zhao, Wei Zhang, Wei Zhang, Jonas T. Schnider, Vasil E. Erbas, Sinan Oksuz, Jan A. Plock, Lisa Rohan, Lisa Rohan, Alexander M. Spiess, Lydia M. Ferreira, Mario G. Solari, Raman Venkataramanan, Raman Venkataramanan, Vijay S. Gorantla, Vijay S. Gorantla, Vijay S. Gorantla

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Rapid and Sensitive Assessment of Human Hepatocyte Functions by Roberto Gramignoli, Veysel Tahan, Kenneth Dorko, Raman Venkataramanan, Ira J. Fox, Ewa C. S. Ellis, Massoud Vosough, Stephen C. Strom Ph.D.

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A pilot study of oral treprostinil pharmacogenomics and treatment persistence in patients with pulmonary arterial hypertension by James C. Coons, Karryn Crisamore, Solomon Adams, Ashley Modany, Marc A. Simon, Wenchen Zhao, Imam H. Shaik, Raman Venkataramanan, Philip E. Empey

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An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy by Yichao Chen, Rui Xia, Yixian Huang, Wenchen Zhao, Jiang Li, Xiaolan Zhang, Pengcheng Wang, Raman Venkataramanan, Jie Fan, Wen Xie, Xiaochao Ma, Binfeng Lu, Song Li

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An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat by Yolandi van der Merwe, Anne E. Faust, Ian Conner, Xinzhu Gu, Firuz Feturi, Wenchen Zhao, Bianca Leonard, Souvik Roy, Vijay S. Gorantla, Raman Venkataramanan, Kia M. Washington, William R. Wagner, Michael B. Steketee

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Abstract 51: Correlative Metrics of Adherence to Immunosuppression in Upper Extremity Transplant Recipients - Pittsburgh Experience by Firuz G. Feturi, PhD, Vincent Chavanon, MD, Jaimie Shores, MD, Gerald Brandacher, MD, Andrew Lee, MD, Joseph Losee, MD, Kia Washington, MD, Mario G. Solari, MD, Raman Venkataramanan, PhD, Vijay Gorantla, MD, Alexander M. Spiess, MD

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Development and Application of Purified Tissue Dissociation Enzyme Mixtures for Human Hepatocyte Isolation by Roberto Gramignoli, Michael L. Green, Veysel Tahan, Kenneth Dorko, Kristen J. Skvorak, Fabio Marongiu, Wenchen Zao, Raman Venkataramanan, Ewa C. S. Ellis, David Geller, Andrew G. Breite, Francis E. Dwulet, Robert C. McCarthy, Stephen C. Strom Ph.D.

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Abstract 84: Single Locally Implanted Tacrolimus Disk Promotes Long-term Vascularized Composite Allograft Survival via Site Specific Immunosuppression and without Systemic Side Eff... by Firuz G. Feturi, PhD, Jignesh Unadkat, MD, Yong Wang, MD, Chiaki Komatsu, MD, Wensheng Zhang, MD, Jingjing Li, MD, Damian Grybowski, MD, Zhaoxiang Zhang, MD, Kia Washington, MD, Mario Solari, MD, Raman Venkataramanan, PhD, Alexander Spiess, MD

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Nerve Wrap for Local Delivery of FK506/Tacrolimus Accelerates Nerve Regeneration by Bo Xiao, Firuz Feturi, An-Jey A. Su, Yolandi Van der Merwe, Joshua M. Barnett, Kayvon Jabbari, Neil J. Khatter, Bing Li, Evan B. Katzel, Raman Venkataramanan, Mario G. Solari, William R. Wagner, Michael B. Steketee, Daniel J. Simons, Kia M. Washington

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SP03. Pharmacokinetics of Rapamycin and Tacrolimus in Swine Model of Vascularized Composite Allotransplantation by Firuz G. Feturi, B. Pharm, PhD, Tarek Y. Elgendy, MD, Deokyeol Kim, MD, Matthias Waldner, MD, Kia M. Washington, MD, Mohamed Ezzelarab, MD, Jignesh V. Unadkat, MD, Angus Thomson, MD, PhD, Mario G. Solari, MD, Raman Venkataramanan, PhD

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Abstract 132: Local Administration of FK506 with Impregnated Nerve Wraps Accelerates Nerve Regeneration by Joshua M. Barnett, BS, Bo Xiao, BS, Yolandi van der Merwe, BS, Xinzhu Gu, PhD, Firuz Feturi, BS, Evan Katzel, MD, Raman Venkataramanan, PhD, Mario Solari, MD, William Wagner, PhD, Daniel Simons, PhD, Michael B. Steketee, PhD, Kia M. Washington, MD

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Trajectories of Depressive and Anxiety Symptoms Across Pregnancy and Postpartum in Selective Serotonin Reuptake Inhibitor‐Treated Women by Gabrielle A. Mesches, Jody D. Ciolino, Catherine S. Stika, Dorothy K. Sit, Katelyn Zumpf, Sheehan Fisher, Crystal T. Clark, Alfred L. George Jr., Michael J. Avram, Laura J. Rasmussen‐Torvik, Daniel L. Erickson, Steven Caritis, Dawn Fischer, Raman Venkataramanan, Maged Costantine, Holly West, Elizabeth Welch, Shannon Clark, Katherine L. Wisner, Jacqueline K. Gollan

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Abstract: Local Administration of FK506 with Impregnated Nerve Wraps Accelerates Peripheral Nerve Regeneration by Joshua M. Barnett, BS, Bo Xiao, MD, PhD, Firuz Feturi, PhD, Yolandi van der Merwe, BEng, Xinzhu Gu, PhD, Evan B. Katzel, MD, Raman Venkataramanan, PhD, Mario G. Solari, MD, William Wagner, PhD, Daniel J. Simons, PhD, Michael B. Steketee, PhD, Kia M. Washington, MD

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