A Review of Epidermal Growth Factor Receptor/HER2 Inhibitors in the Treatment of Patients with Non–Small-Cell Lung Cancer by Ramaswamy GOVINDAN

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Untangling the evolutionary roots of lung cancer by Siddhartha Devarakonda, Ramaswamy Govindan

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Effect of metastatic site on survival in patients with neuroendocrine neoplasms (NENs). An analysis of SEER data from 2010 to 2014 by Nikolaos A. Trikalinos, Benjamin R. Tan, Manik Amin, Jingxia Liu, Ramaswamy Govindan, Daniel Morgensztern

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Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers by Jennifer A. Karlow, Erica C. Pehrsson, Xiaoyun Xing, Mark Watson, Siddhartha Devarakonda, Ramaswamy Govindan, Ting Wang

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278 Phase I clinical trial evaluating the safety of ADP-A2M10 SPEAR T-cells in patients with MAGE-A10+ advanced non-small cell lung cancer by Victor Moreno, Ramaswamy Govindan, George Blumenschein, Siddhartha Devarakonda, Melissa Johnson, Carlos Bachier, Bernard Doger de Spéville, Vincent Lam, Natalie Hyland

Long non-coding RNA LCAL62 / LINC00261 is associated with lung adenocarcinoma prognosis by Ha X. Dang, Nicole M. White, Emily B. Rozycki, Brooke M. Felsheim, Mark A. Watson, Ramaswamy Govindan, Jingqin Luo, Christopher A. Maher

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Exploring the Feasibility of Utilizing Limited Gene Panel Circulating Tumor DNA Clearance as a Biomarker in Patients With Locally Advanced Non-Small Cell Lung Cancer by Brendan Knapp, Laura Mezquita, Siddhartha Devarakonda, Mihaela Aldea, Saiama N. Waqar, Kym Pepin, Jeffrey P. Ward, Angela Botticella, Karen Howarth, Charlene Knape, Clive Morris, Ramaswamy Govindan, Benjamin Besse, Daniel Morgensztern

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Pre-radiotherapy ctDNA liquid biopsy for risk stratification of oligometastatic non-small cell lung cancer by Nicholas P. Semenkovich, Shahed N. Badiyan, Pamela P. Samson, Hayley B. Stowe, Yun E. Wang, Rachel Star, Siddhartha Devarakonda, Ramaswamy Govindan, Saiama N. Waqar, Clifford G. Robinson, Gregory Vlacich, Bruna Pellini, Aadel A. Chaudhuri

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nab-Paclitaxel Plus Durvalumab in Patients With Previously Treated Advanced Stage Non-small Cell Lung Cancer (ABOUND.2L+) by Daniel Morgensztern, Manuel Cobo Dols, Santiago Ponce Aix, Pieter E. Postmus, Jaafar Bennouna, Jürgen R. Fischer, Oscar Juan-Vidal, David J. Stewart, Andrea Ardizzoni, Rafia Bhore, Marianne Wolfsteiner, Martin Reck, Denis Talbot, Ramaswamy Govindan, Teng Jin Ong

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364 A personal neoantigen vaccine NEO-PV-01 in combination with chemotherapy and pembrolizumab induces broad de novo immune responses in first line, non-squamous NSCLC by Saiama Waqar, Mark Awad, Ramaswamy Govindan, David Spigel, Richard Gaynor, Edward Garon, Aaron Lisberg, Melissa Moles, Jennifer Tepper, April Lamb, Amy Wanamaker, Zakaria Khondker, John Srouji, Jesse Dong, Asaf Poran, Kristen Balogh, Meghan Bushway, Mark DeMario, Lakshmi Srinivasan

Translatability of findings from cynomolgus monkey to human suggests a mechanistic role for IL-21 in promoting immunogenicity to an anti-PD-1/IL-21 mutein fusion protein by Mark A. Kroenke, Marta Starcevic Manning, Christina L. Zuch de Zafra, Xinwen Zhang, Kevin D. Cook, Michael Archer, Martijn P. Lolkema, Jin Wang, Sarah Hoofring, Gurleen Saini, Famke Aeffner, Elizabeth Ahern, Elena Garralda Cabanas, Ramaswamy Govindan, Mun Hui, Shalini Gupta, Daniel T. Mytych

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P079: ClinGen Somatic and CIViC collaborate to comprehensively evaluate somatic variants in cancer* by Jason Saliba, Arpad Danos, Kilannin Krysiak, Adam Coffman, Susanna Kiwala, Joshua McMichael, Cameron Grisdale, Ian King, Shamini Selvarajah, Xinjie Xu, Rashmi Kanagal-Shamanna, Laveniya Satgunaseelan, David Meredith, Mark Evans, Charles Mullighan, Yassmine Akkari, Gordana Raca, Angshumoy Roy, Alex Wagner, Ramaswamy Govindan, Obi Griffith, Malachi Griffith

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359 AMG 757, a half-life extended bispecific T-cell engager (BiTE®) immune therapy against DLL3 in SCLC: phase 1 interim results by Hui Yang, Stephane Champiat, Ramaswamy Govindan, Ravi Salgia, Fiona Blackhall, Everett Vokes, Michael Boyer, Marie-Anne Damiette Smit, Melissa Johnson, Hossein Borghaei, Luis Paz-Ares Rodrigues, Rene Boosman, Horst-Dieter Hummel, W Victoria Lai, Hibiki Udagawa, Anne Chiang, Christine Hann, Mukul Minocha, Nooshin Hashemi-Sadraei, Aditya Shetty, Taofeek Owonikoko

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma by Raffit Hassan, Patrick M Forde, Edward B Garon, Steven M Dubinett, Roy S Herbst, Charu Aggarwal, Matthew D Hellmann, Sarah B Goldberg, David L Rimm, Sarah Sagorsky, Boris Sepesi, Ramaswamy Govindan, Andrea Ferris, Scott J Antonia, Fred R Hirsch, Lawrence H Schwartz, Marianne Davies, Melissa L Johnson, Shakun Malik, Daniel Morgensztern, Joel W Neal, Jyoti D Patel

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Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer by Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu, Megan Richters, Sharon L. Freshour, Zachary L. Skidmore, Huiming Xia, Joshua F. McMichael, Jason Kunisaki, Katie M. Campbell, Timothy Hung-Po Chen, Emily B. Rozycki, Douglas Adkins, Siddhartha Devarakonda, Sumithra Sankararaman, Yiing Lin, William C. Chapman, Christopher A. Maher, Vivek Arora, Gavin P. Dunn, Ravindra Uppaluri, Ramaswamy Govindan, Obi L. Griffith, Malachi Griffith

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Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy by Catherine G. Tran, Luis C. Borbon, Jacqueline L. Mudd, Ellen Abusada, Solmaz AghaAmiri, Sukhen C. Ghosh, Servando Hernandez Vargas, Guiying Li, Gabriella V. Beyer, Mary McDonough, Rachel Li, Carlos H.F. Chan, Susan A. Walsh, Thaddeus J. Wadas, Thomas O’Dorisio, M Sue O’Dorisio, Ramaswamy Govindan, Paul F. Cliften, Ali Azhdarinia, Andrew M. Bellizzi, Ryan C. Fields, James R. Howe, Po Hien Ear

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Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10+ advanced non-small cell lung cancer by Victor Moreno, Andrew Gerry, Tom Holdich, Anthony J Olszanski, Ramaswamy Govindan, John V Heymach, Matthew J Frigault, Siddhartha Devarakonda, Melissa Johnson, Justin Gainor, Carlos Bachier, Natalie Hyland, Jean-Marc Navenot, Svetlana Fayngerts, Jane Bai, Elliot Norry, Robyn Broad, George R Blumenschein, Martin J Edelman, Bernard Doger de Spéville, Vincent K Lam, Zohar Wolchinsky, Dzmitry Batrakou, Melissa M Pentony, Joseph P Sanderson, Diane Marks, Paula M Fracasso

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Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer by Ashenafi Bulle, Peng Liu, Kuljeet Seehra, Sapana Bansod, Yali Chen, Kiran Zahra, Vikas Somani, Iftikhar Ali Khawar, Hung-Po Chen, Paarth B. Dodhiawala, Lin Li, Yutong Geng, Chia-Kuei Mo, Jay Mahsl, Li Ding, Ramaswamy Govindan, Sherri Davies, Jacqueline Mudd, William G. Hawkins, Ryan C. Fields, David G. DeNardo, Deborah Knoerzer, Jason M. Held, Patrick M. Grierson, Andrea Wang-Gillam, Marianna B. Ruzinova, Kian-Huat Lim

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Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer by Alex H. Wagner, Siddhartha Devarakonda, Zachary L. Skidmore, Kilannin Krysiak, Avinash Ramu, Lee Trani, Jason Kunisaki, Ashiq Masood, Saiama N. Waqar, Nicholas C. Spies, Daniel Morgensztern, Jason Waligorski, Jennifer Ponce, Robert S. Fulton, Leonard B. Maggi, Jason D. Weber, Mark A. Watson, Christopher J. O’Conor, Jon H. Ritter, Rachelle R. Olsen, Haixia Cheng, Anandaroop Mukhopadhyay, Ismail Can, Melissa H. Cessna, Trudy G. Oliver, Elaine R. Mardis, Richard K. Wilson, Malachi Griffith, Obi L. Griffith, Ramaswamy Govindan

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Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment by Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding

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