Reg3γ: current understanding and future therapeutic opportunities in metabolic disease by Jae Hoon Shin, Nadejda Bozadjieva-Kramer, Randy J. Seeley

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Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose by Henriette Frikke-Schmidt, Peter Arvan, Randy J. Seeley, Corentin Cras-Méneur

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High fat diet alters lactation outcomes: possible involvement of inflammatory and serotonergic pathways. by Laura L Hernandez, Bernadette E Grayson, Ekta Yadav, Randy J Seeley, Nelson D Horseman

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GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice by Henriette Frikke-Schmidt, Karin Hultman, Joseph W. Galaske, Sebastian B. Jørgensen, Martin G. Myers, Jr., Randy J. Seeley

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Weight loss independent changes in adipose tissue macrophage and T cell populations after sleeve gastrectomy in mice by Henriette Frikke-Schmidt, Brian F. Zamarron, Robert W. O'Rourke, Darleen A. Sandoval, Carey N. Lumeng, Randy J. Seeley

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Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action by Elodie M. Varin, Erin E. Mulvihill, Laurie L. Baggio, Jacqueline A. Koehler, Xiemin Cao, Randy J. Seeley, Daniel J. Drucker

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The anorectic effect of GLP-1 in rats is nutrient dependent. by Darleen Sandoval, Jason G Barrera, Margaret A Stefater, Stephanie Sisley, Stephen C Woods, David D D'Alessio, Randy J Seeley

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High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney by Kerstin Stemmer, Diego Perez-Tilve, Gayathri Ananthakrishnan, Anja Bort, Randy J. Seeley, Matthias H. Tschöp, Daniel R. Dietrich, Paul T. Pfluger

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Intestinal HIF-2α Regulates GLP-1 Secretion via Lipid Sensing in L-CellsSummary by Raja Gopal Reddy Mooli, Dhanunjay Mukhi, Anil K. Pasupulati, Simon S. Evers, Ian J. Sipula, Michael Jurczak, Randy J. Seeley, Yatrik M. Shah, Sadeesh K. Ramakrishnan

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Vertical sleeve gastrectomy induces enteroendocrine cell differentiation of intestinal stem cells through bile acid signaling by Ki-Suk Kim, Bailey C.E. Peck, Yu-Han Hung, Kieran Koch-Laskowski, Landon Wood, Priya H. Dedhia, Jason R. Spence, Randy J. Seeley, Praveen Sethupathy, Darleen A. Sandoval

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GDF15 is required for cold-induced thermogenesis and contributes to improved systemic metabolic health following loss of OPA1 in brown adipocytes by Jayashree Jena, Luis Miguel García-Peña, Eric T Weatherford, Alex Marti, Sarah H Bjorkman, Kevin Kato, Jivan Koneru, Jason H Chen, Randy J Seeley, E Dale Abel, Renata O Pereira

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Continuous glucose monitoring reveals glycemic variability and hypoglycemia after vertical sleeve gastrectomy in rats by Simon S. Evers, Ki-Suk Kim, Nadejda Bozadjieva, Alfor G. Lewis, Diana Farris, Matthew J. Sorensen, Youngsoo Kim, Steven E. Whitesall, Robert T. Kennedy, Daniel E. Michele, Randy J. Seeley, Darleen A. Sandoval

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The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice by Laurie L. Baggio, John R. Ussher, Brent A. McLean, Xiemin Cao, M. Golam Kabir, Erin E. Mulvihill, Alexandra S. Mighiu, Hangjun Zhang, Andreas Ludwig, Randy J. Seeley, Scott P. Heximer, Daniel J. Drucker

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Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity. by Ji-Yeon Lee, Heike Muenzberg, Oksana Gavrilova, Jacquelyn A Reed, Darlene Berryman, Eneida C Villanueva, Gwendolyn W Louis, Gina M Leinninger, Stefano Bertuzzi, Randy J Seeley, Gertraud W Robinson, Martin G Myers, Lothar Hennighausen

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Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation by Danna M. Breen, Srinath Jagarlapudi, Anita Patel, Chang Zou, Stephanie Joaquim, Xiangping Li, Liya Kang, Jincheng Pang, Katherine Hales, Enida Ziso-Qejvanaj, Nicholas B. Vera, Donald Bennett, Tao He, Matthew Lambert, Kerry Kelleher, Zhidan Wu, Bei B. Zhang, Laura Lin, Randy J. Seeley, Olivier Bezy

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Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models by Alan C. Rupp, Abigail J. Tomlinson, Alison H. Affinati, Warren T. Yacawych, Allison M. Duensing, Cadence True, Sarah R. Lindsley, Melissa A. Kirigiti, Alexander MacKenzie, Joseph Polex-Wolf, Chien Li, Lotte Bjerre Knudsen, Randy J. Seeley, David P. Olson, Paul Kievit, Martin G. Myers Jr.

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Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation by Silvana Obici, I. Jack Magrisso, Armen S. Ghazarian, Alireza Shirazian, Jonas R. Miller, Christine M. Loyd, Denovan P. Begg, Kimberly A. Krawczewski Carhuatanta, Michael K. Haas, Jon F. Davis, Stephen C. Woods, Darleen A. Sandoval, Randy J. Seeley, Laurie J. Goodyear, Emmanuel N. Pothos, Joram D. Mul

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Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity by Anne-Marie C. Overstreet, Bernadette E. Grayson, Antonia Boger, Danika Bakke, Erin M. Carmody, Cayla E. Bales, Shirley C. Paski, Stephen F. Murphy, Christopher R. Dethlefs, Kara J. Shannon, Katie R. Adlaka, Claire E. Wolford, Vincent J. Campiti, Christina V. Raghunandan, Randy J. Seeley, David L. Boone

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Dietary sugars, not lipids, drive hypothalamic inflammation by Yuanqing Gao, Maximilian Bielohuby, Thomas Fleming, Gernot F. Grabner, Ewout Foppen, Wagner Bernhard, Mara Guzmán-Ruiz, Clarita Layritz, Beata Legutko, Erwin Zinser, Cristina García-Cáceres, Ruud M. Buijs, Stephen C. Woods, Andries Kalsbeek, Randy J. Seeley, Peter P. Nawroth, Martin Bidlingmaier, Matthias H. Tschöp, Chun-Xia Yi

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Calorie restriction outperforms bariatric surgery in a murine model of obesity and triple-negative breast cancer by Kristina K. Camp, Michael F. Coleman, Tori L. McFarlane, Steven S. Doerstling, Subreen A. Khatib, Erika T. Rezeli, Alfor G. Lewis, Alexander J. Pfeil, Laura A. Smith, Laura W. Bowers, Farnaz Fouladi, Weida Gong, Elaine M. Glenny, Joel S. Parker, Ginger L. Milne, Ian M. Carroll, Anthony A. Fodor, Randy J. Seeley, Stephen D. Hursting

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