Human Autoinflammatory Diseases Mediated by NLRP3-, Pyrin-, NLRP1-, and NLRC4-Inflammasome Dysregulation Updates on Diagnosis, Treatment, and the Respective Roles of IL-1 and IL-18 by Sara Alehashemi, Raphaela Goldbach-Mansky

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Editorial: Insights in autoimmune and autoinflammatory disorders: 2021 by Raphaela Goldbach-Mansky, Betty Diamond

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Human induced pluripotent stem cells generated from Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome patients with a homozygou... by Quan Yu, Atul Mehta, Jizhong Zou, Jeanette Beers, Adriana A de Jesus Rasheed, Raphaela Goldbach-Mansky, Manfred Boehm, Guibin Chen

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Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene by Rebecca Harper, Quan Yu, Yangtenyu Liu, Dan Yang, Jizhong Zou, Jeanette Beers, Adriana A. de Jesus Rasheed, Raphaela Goldbach-Mansky, Manfred Boehm, Guibin Chen

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Corrigendum to “Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene” [Stem Cell Res. 64 (2022) 102933] by Rebecca Harper, Quan Yu, Yangtenyu Liu, Dan Yang, Jizhong Zou, Jeanette Beers, Adriana A de Jesus Rasheed, Raphaela Goldbach-Mansky, Manfred Boehm, Guibin Chen

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Human induced pluripotent stem cells generated from STING-associated vasculopathy with onset in infancy (SAVI) patients with a heterozygous mutation in the STING gene by Atul Mehta, Quan Yu, Yangtengyu Liu, Dan Yang, Jizhong Zou, Jeanette Beers, Adriana A de Jesus Rasheed, Andrew T. Rastegar, Raphaela Goldbach-Mansky, Manfred Boehm, Guibin Chen

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Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib by Ali Jabbari, Zhenpeng Dai, Luzhou Xing, Jane E. Cerise, Yuval Ramot, Yackov Berkun, Gina A. Montealegre Sanchez, Raphaela Goldbach-Mansky, Angela M. Christiano, Raphael Clynes, Abraham Zlotogorski

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Human induced pluripotent stem cells (NIHTVBi029-A and NIHTVBi030-A) generated from two patients with a heterozygous mutation in the CDC42 gene by Isabella Varea, Benjamin Joseph, Kevin Emmerich, Sahana Manohar-Sindhu, Jizhong Zou, Kip Friend, Xuming Tang, Dan Yang, Adriana A de Jesus Rasheed, Raphaela Goldbach-Mansky, Manfred Boehm

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Establishment of a human induced pluripotent stem cell line (NIHTVBi031-A) derived from a COPA syndrome patient with a heterozygous p.Ala239Pro mutation by Benjamin Joseph, Isabella Varea, Kevin Emmerich, Sahana Manohar-Sindhu, Jizhong Zou, Kip Friend, Caleb Sipwoli, Xuming Tang, Dan Yang, Adriana A de Jesus Rasheed, Raphaela Goldbach-Mansky, Manfred Boehm

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Development of nitroalkene-based inhibitors to target STING-dependent inflammation by Fei Chang, Camilla Gunderstofte, Nicole Colussi, Mareena Pitts, Sonia R. Salvatore, Anne L. Thielke, Lucia Turell, Beatriz Alvarez, Raphaela Goldbach-Mansky, Luis Villacorta, Christian K. Holm, Francisco J. Schopfer, Anne Louise Hansen

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Proceedings from the 2nd Next Gen Therapies for Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome symposium held on October 3-4, 2019 by Scott W. Canna, Grant S. Schulert, Adriana de Jesus, Alex Pickering, Hermine Brunner, Massimo Gadina, Stewart Levine, Raphaela Goldbach-Mansky, Jonathan Boutelle, Rashmi Sinha, Fabrizio DeBenedetti, Alexei Grom, on behalf of the NextGen 2019 Participants

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Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies by Hanna Kim, Fatima Gunter-Rahman, John A. McGrath, Esther Lee, Adriana A. de Jesus, Ira N. Targoff, Yan Huang, Terrance P. O’Hanlon, Wanxia L. Tsai, Massimo Gadina, Frederick W. Miller, Raphaela Goldbach-Mansky, Lisa G. Rider

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Case Report: Novel SAVI-Causing Variants in STING1 Expand the Clinical Disease Spectrum and Suggest a Refined Model of STING Activation by Bin Lin, Sofia Torreggiani, Dana Kahle, Dax G. Rumsey, Benjamin L. Wright, Benjamin L. Wright, Marco A. Montes-Cano, Laura Fernandez Silveira, Sara Alehashemi, Jacob Mitchell, Alexander G. Aue, Zheng Ji, Tengchuan Jin, Adriana A. de Jesus, Raphaela Goldbach-Mansky

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Case report: De novo SAMD9L truncation causes neonatal-onset autoinflammatory syndrome which was successfully treated with hematopoietic stem cell transplantation by María Soledad Caldirola, María Soledad Caldirola, Analía Gisela Seminario, Analía Gisela Seminario, Paula Carolina Luna, Renata Curciarello, Guillermo Horacio Docena, Nicolás Fernandez Escobar, Guillermo Drelichman, Marco Gattorno, Adriana A. de Jesus, Raphaela Goldbach-Mansky, María Isabel Gaillard, María Isabel Gaillard, Liliana Bezrodnik

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Autoinflammatory patients with Golgi-trapped CDC42 exhibit intracellular trafficking defects leading to STING hyperactivation and ER stress by Alberto Iannuzzo, Selket Delafontaine, Rana El Masri, Rachida Tacine, Giusi Prencipe, Masahiko Nishitani-Isa, Rogier T. A. van Wijck, Farzana Bhuyan, Adriana A. de Jesus Rasheed, Simona Coppola, Paul L. A. van Daele, Antonella Insalaco, Raphaela Goldbach-Mansky, Takahiro Yasumi, Marco Tartaglia, Isabelle Meyts, Jérôme Delon

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Establishing 20S Proteasome Genetic, Translational and Post-Translational Status from Precious Biological and Patient Samples with Top-Down MS by Angelique Sanchez Dafun, Dušan Živković, Stephen Adonai Leon-Icaza, Sophie Möller, Carine Froment, Delphine Bonnet, Adriana Almeida de Jesus, Laurent Alric, Muriel Quaranta-Nicaise, Audrey Ferrand, Céline Cougoule, Etienne Meunier, Odile Burlet-Schiltz, Frédéric Ebstein, Raphaela Goldbach-Mansky, Elke Krüger, Marie-Pierre Bousquet, Julien Marcoux

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Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1β. by Pamela Aubert, Mayte Suárez-Fariñas, Hiroshi Mitsui, Leanne M Johnson-Huang, Jamie Lynn Harden, Katherine C Pierson, Joseph G Dolan, Inna Novitskaya, Israel Coats, Jacob Estes, Edward W Cowen, Nicole Plass, Chyi-Chia Richard Lee, Hong-Wei Sun, Michelle A Lowes, Raphaela Goldbach-Mansky

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IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE by Shu Wang, Jingya Wang, Varsha Kumar, Jodi L. Karnell, Brian Naiman, Phillip S. Gross, Saifur Rahman, Kamelia Zerrouki, Richard Hanna, Christopher Morehouse, Nicholas Holoweckyj, Hao Liu, Autoimmunity Molecular Medicine Team, Zerai Manna, Raphaela Goldbach-Mansky, Sarfaraz Hasni, Richard Siegel, Miguel Sanjuan, Katie Streicher, Michael P. Cancro, Roland Kolbeck, Rachel Ettinger

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Spectrum of Systemic Auto-Inflammatory Diseases in India: A Multi-Centric Experience by Deepti Suri, Amit Rawat, Ankur Kumar Jindal, Pandiarajan Vignesh, Anju Gupta, Rakesh Kumar Pilania, Vibhu Joshi, Kanika Arora, Rajni Kumrah, Gummadi Anjani, Amita Aggarwal, Shubha Phadke, Fouzia N. Aboobacker, Biju George, Eunice Sindhuvi Edison, Mukesh Desai, Prasad Taur, Vijaya Gowri, Ambreen Abdulwahab Pandrowala, Sagar Bhattad, Swati Kanakia, Marco Gottorno, Isabella Ceccherini, Adriana Almeida de Jesus, Raphaela Goldbach-Mansky, Michael S. Hershfield, Surjit Singh

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Genetically programmed alternative splicing of NEMO mediates an autoinflammatory disease phenotype by Younglang Lee, Alex W. Wessel, Jiazhi Xu, Julia G. Reinke, Eries Lee, Somin M. Kim, Amy P. Hsu, Jevgenia Zilberman-Rudenko, Sha Cao, Clinton Enos, Stephen R. Brooks, Zuoming Deng, Bin Lin, Adriana A. de Jesus, Daniel N. Hupalo, Daniela G.P. Piotto, Maria T. Terreri, Victoria R. Dimitriades, Clifton L. Dalgard, Steven M. Holland, Raphaela Goldbach-Mansky, Richard M. Siegel, Eric P. Hanson

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