Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression. by Lindsay M Reynolds, Timothy D Howard, Ingo Ruczinski, Kanika Kanchan, Michael C Seeds, Rasika A Mathias, Floyd H Chilton

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Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation. by Yoonhee Kim, Bhoom Suktitipat, Lisa R Yanek, Nauder Faraday, Alexander F Wilson, Diane M Becker, Lewis C Becker, Rasika A Mathias

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On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies. by Sungho Won, Jemma B Wilk, Rasika A Mathias, Christopher J O'Donnell, Edwin K Silverman, Kathleen Barnes, George T O'Connor, Scott T Weiss, Christoph Lange

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Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer’s disease by Megan T. Lynch, Margaret A. Taub, Jose M. Farfel, Jingyun Yang, Peter Abadir, Philip L. De Jager, Francine Grodstein, David A. Bennett, Rasika A. Mathias

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Adaptive evolution of the FADS gene cluster within Africa. by Rasika A Mathias, Wenqing Fu, Joshua M Akey, Hannah C Ainsworth, Dara G Torgerson, Ingo Ruczinski, Susan Sergeant, Kathleen C Barnes, Floyd H Chilton

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Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families by Ali R Keramati, Lisa R Yanek, Kruthika Iyer, Margaret A Taub, Ingo Ruczinski, Diane M Becker, Lewis C Becker, Nauder Faraday, Rasika A Mathias

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FADS genetic variants and ω-6 polyunsaturated fatty acid metabolism in a homogeneous island population[S] by Rasika A. Mathias, Candelaria Vergara, Li Gao, Nicholas Rafaels, Tracey Hand, Monica Campbell, Carol Bickel, Priscilla Ivester, Susan Sergeant, Kathleen C. Barnes, Floyd H. Chilton

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Aquaporin 5 polymorphisms and rate of lung function decline in chronic obstructive pulmonary disease. by Nadia N Hansel, Venkataramana Sidhaye, Nicholas M Rafaels, Li Gao, Peisong Gao, Renaldo Williams, John E Connett, Terri H Beaty, Rasika A Mathias, Robert A Wise, Landon S King, Kathleen C Barnes

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Telomere shortening and the transition to family caregiving in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. by Nicole D Armstrong, Marguerite R Irvin, William E Haley, Marcela D Blinka, Debora Kamin Mukaz, Amit Patki, Sue Rutherford Siegel, Idan Shalev, Peter Durda, Rasika A Mathias, Jeremy D Walston, David L Roth

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HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy by Kanika Kanchan, Stepan Grinek, Henry T. Bahnson, Ingo Ruczinski, Gautam Shankar, David Larson, George Du Toit, Kathleen C. Barnes, Hugh A. Sampson, Mayte Suarez-Farinas, Gideon Lack, Gerald T. Nepom, Karen Cerosaletti, Rasika A. Mathias

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Telomere shortening and the transition to family caregiving in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study by Nicole D. Armstrong, Marguerite R. Irvin, William E. Haley, Marcela D. Blinka, Debora Kamin Mukaz, Amit Patki, Sue Rutherford Siegel, Idan Shalev, Peter Durda, Rasika A. Mathias, Jeremy D. Walston, David L. Roth

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DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver. by Timothy D Howard, Rasika A Mathias, Michael C Seeds, David M Herrington, James E Hixson, Lawrence C Shimmin, Greg A Hawkins, Matthew Sellers, Hannah C Ainsworth, Susan Sergeant, Leslie R Miller, Floyd H Chilton

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Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis. by Kai Kammers, Margaret A Taub, Ingo Ruczinski, Joshua Martin, Lisa R Yanek, Alyssa Frazee, Yongxing Gao, Dixie Hoyle, Nauder Faraday, Diane M Becker, Linzhao Cheng, Zack Z Wang, Jeff T Leek, Lewis C Becker, Rasika A Mathias

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Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis. by Mary J Emond, Tin Louie, Julia Emerson, Jessica X Chong, Rasika A Mathias, Michael R Knowles, Mark J Rieder, Holly K Tabor, Debbie A Nickerson, Kathleen C Barnes, NHLBI GO Exome Sequencing Project, Lung Go, Ronald L Gibson, Michael J Bamshad

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Correction: Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis. by Mary J Emond, Tin Louie, Julia Emerson, Jessica X Chong, Rasika A Mathias, Michael R Knowles, Mark J Rieder, Holly K Tabor, Debbie A Nickerson, Kathleen C Barnes, NHLBI GO Exome Sequencing Project, Lung Go, Ronald L Gibson, Michael J Bamshad

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Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI by Quan Sun, Bryce T. Rowland, Jiawen Chen, Anna V. Mikhaylova, Christy Avery, Ulrike Peters, Jessica Lundin, Tara Matise, Steve Buyske, Ran Tao, Rasika A. Mathias, Alexander P. Reiner, Paul L. Auer, Nancy J. Cox, Charles Kooperberg, Timothy A. Thornton, Laura M. Raffield, Yun Li

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HLA-associated outcomes in peanut oral immunotherapy trials identify mechanistic and clinical determinants of therapeutic success by Kanika Kanchan, Gautam Shankar, Michelle F. Huffaker, Henry T. Bahnson, Henry T. Bahnson, R Sharon Chinthrajah, Srinath Sanda, Monali Manohar, Hua Ling, Justin E. Paschall, George Du Toit, Ingo Ruczinski, Alkis Togias, Gideon Lack, Kari C. Nadeau, Stacie M. Jones, Gerald T. Nepom, Gerald T. Nepom, Rasika A. Mathias

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Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry by Michael D. Kessler, Laura Yerges-Armstrong, Margaret A. Taub, Amol C. Shetty, Kristin Maloney, Linda Jo Bone Jeng, Ingo Ruczinski, Albert M. Levin, L. Keoki Williams, Terri H. Beaty, Rasika A. Mathias, Kathleen C. Barnes, Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA), Timothy D. O’Connor

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Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation by Ming-Huei Chen, Lisa R. Yanek, Joshua D. Backman, John D. Eicher, Jennifer E. Huffman, Yoav Ben-Shlomo, Andrew D. Beswick, Laura M. Yerges-Armstrong, Alan R. Shuldiner, Jeffrey R. O’Connell, Rasika A. Mathias, Diane M. Becker, Lewis C. Becker, Joshua P. Lewis, Andrew D. Johnson, Nauder Faraday

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Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program by Kanika Kanchan, Kruthika Iyer, Lisa R Yanek, Ivan Carcamo-Orive, Margaret A Taub, Claire Malley, Kristin Baldwin, Lewis C Becker, Ulrich Broeckel, Linzhao Cheng, Chad Cowan, Matteo D'Antonio, Kelly A Frazer, Thomas Quertermous, Gustavo Mostoslavsky, George Murphy, Marlene Rabinovitch, Daniel J Rader, Martin H Steinberg, Eric Topol, Wenli Yang, Joshua W Knowles, Cashell E Jaquish, Ingo Ruczinski, Rasika A Mathias

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