Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma by Lafleur, VN, Halim, S, Choudhry, H, Ratcliffe, PJ, Mole, DR

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature by Lombardi, O, Li, R, Halim, S, Choudhry, H, Ratcliffe, PJ, Mole, DR

Factor inhibiting HIF (FIH1) modulates cardiac function and metabolism by Holliday, J, Platt, S, Handzlik, MK, MacDonald, IA, Clarke, K, Ratcliffe, PJ, Cole, MA

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2 by Choudhry, H, Schödel, J, Oikonomopoulos, S, Camps, C, Grampp, S, Harris, AL, Ratcliffe, PJ, Ragoussis, J, Mole, DR

N-terminal cysteine acetylation and oxidation patterns may define protein stability by Heathcote, KC, Keeley, TP, Myllykoski, M, Lundekvam, M, McTiernan, N, Akter, S, Masson, N, Ratcliffe, PJ, Arnesen, T, Flashman, E

Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6 by Cockman, ME, Sugimoto, Y, Pegg, HB, Masson, N, Salah, E, Tumber, A, Flynn, HR, Kirkpatrick, JM, Schofield, CJ, Ratcliffe, PJ

Hypoxia drives glucose transporter 3 expression through HIF-mediated induction of the long non-coding RNA NICI by Lauer, V, Grampp, S, Platt, J, Lafleur, V, Lombardi, O, Choudhry, H, Kranz, F, Hartmann, A, Wullich, B, Yamamoto, A, Coleman, ML, Ratcliffe, PJ, Mole, DR, Schödel, J

Structure–activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors by Holt-Martyn, JP, Chowdhury, R, Tumber, A, Yeh, T-L, Abboud, MI, Lippl, K, Lohans, CT, Langley, GW, Figg Jr, W, McDonough, MA, Pugh, CW, Ratcliffe, PJ, Schofield, CJ

The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes by Ortmann, BM, Burrows, N, Lobb, IT, Arnaiz, E, Wit, N, Bailey, PSJ, Jordon, LH, Lombardi, O, Peñalver, A, McCaffrey, J, Seear, R, Mole, DR, Ratcliffe, PJ, Maxwell, PH, Nathan, JA

Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins by Leissing, TM, Hardy, AP, Chan, H, Wang, Y, Tumber, A, Chowdhury, R, Fang, P, Coleman, ML, Cockman, ME, Kramer, HB, Berridge, G, Fischer, R, Kessler, B, Ratcliffe, PJ, Lu, X, Schofield, CJ

Potent and selective triazole-based inhibitors of the hypoxia-inducible factor prolyl-hydroxylases with activity in the murine brain by Chan, MC, Atasoylu, O, Hodson, E, Tumber, A, Leung, IKH, Chowdhury, R, Gómez-Pérez, V, Demetriades, M, Rydzik, AM, Holt-Martyn, J, Tian, Y-M, Bishop, T, Claridge, TDW, Kawamura, A, Pugh, CW, Ratcliffe, PJ, Schofield, CJ

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases by Markolovic, S, Zhuang, Q, Wilkins, SE, Eaton, CD, Abboud, MI, Katz, MJ, McNeil, HE, Leśniak, R, Hall, C, Struwe, WB, Konietzny, R, Davis, S, Yang, M, Ge, W, Benesch, JLP, Kessler, BM, Ratcliffe, PJ, Cockman, ME, Fischer, R, Wappner, P, Chowdhury, R, Coleman, M, Schofield, CJ

Hypoxic and pharmacological activation of HIFs inhibits SARS-CoV-2 infection of lung epithelial cells by Wing, P, Keeley, TP, Zhuang, X, Lee, JY, Prange-Barczynska, M, Tsukuda, S, Morgan, SB, Harding, AC, Argles, ILA, Kurlekar, S, Noerenberg, M, Thompson, CP, Huang, K-YA, Balfe, P, Watashi, K, Castello, A, Hinks, TSC, James, W, Ratcliffe, PJ, Davis, I, Hodson, EJ, Bishop, T, McKeating, J

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses by Sadiku, P, Willson, JA, Dickinson, RS, Murphy, F, Harris, AJ, Lewis, A, Sammut, D, Mirchandani, AS, Ryan, E, Watts, ER, Thompson, AAR, Marriott, HM, Dockrell, DH, Taylor, CT, Schneider, M, Maxwell, PH, Chilvers, ER, Mazzone, M, Moral, V, Pugh, CW, Ratcliffe, PJ, Schofield, CJ, Ghesquiere, B, Carmeliet, P, Whyte, MK, Walmsley, SR

Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment by Ma, J, Al Moussawi, K, Lou, H, Chan, HF, Wang, Y, Chadwick, J, Phetsouphanh, C, Slee, EA, Zhong, S, Leissing, TM, Roth, A, Qin, X, Chen, S, Yin, J, Ratnayaka, I, Hu, Y, Louphrasitthiphol, P, Taylor, L, Bettencourt, PJG, Muers, M, Greaves, DR, McShane, H, Goldin, R, Soilleux, EJ, Coleman, ML, Ratcliffe, PJ, Lu, X