Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage. by Regina Cencic, Hisashi Miura, Abba Malina, Francis Robert, Sylvain Ethier, T Martin Schmeing, Josée Dostie, Jerry Pelletier

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Selective pharmacological targeting of a DEAD box RNA helicase. by Lisa Lindqvist, Monika Oberer, Mikhail Reibarkh, Regina Cencic, Marie-Eve Bordeleau, Emily Vogt, Assen Marintchev, Junichi Tanaka, Francois Fagotto, Michael Altmann, Gerhard Wagner, Jerry Pelletier

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Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. by Regina Cencic, Marilyn Carrier, Gabriela Galicia-Vázquez, Marie-Eve Bordeleau, Rami Sukarieh, Annie Bourdeau, Brigitte Brem, Jose G Teodoro, Harald Greger, Michel L Tremblay, John A Porco, Jerry Pelletier

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A forward genetic screen identifies modifiers of rocaglate responsiveness by Leo Shen, Lauren Pugsley, Regina Cencic, HanChen Wang, Francis Robert, Sai Kiran Naineni, Ananya Sahni, Geneviève Morin, Wenhan Zhang, Anastasia Nijnik, John A. Porco, David Langlais, Sidong Huang, Jerry Pelletier

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Eukaryotic Translation Initiation Factor 4AI: A Potential Novel Target in Neuroblastoma by Christina Skofler, Florian Kleinegger, Stefanie Krassnig, Anna Maria Birkl-Toeglhofer, Georg Singer, Holger Till, Martin Benesch, Regina Cencic, John A. Porco, Jerry Pelletier, Christoph Castellani, Andrea Raicht, Ewa Izycka-Swieszewska, Piotr Czapiewski, Johannes Haybaeck

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Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F by Jennifer Chu, Wenhan Zhang, Regina Cencic, Patrick B.F. O’Connor, Francis Robert, William G. Devine, Asher Selznick, Thomas Henkel, William C. Merrick, Lauren E. Brown, Pavel V. Baranov, John A. Porco, Jr., Jerry Pelletier

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Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells by Zihao Wang, Ritesh P. Thakare, Shalaka Chitale, Alok K. Mishra, Stanley I. Goldstein, Alice C. Fan, Rui Li, Lihua Julie Zhu, Lauren E. Brown, Regina Cencic, Sidong Huang, Michael R. Green, Jerry Pelletier, Sunil K. Malonia, John A. Porco

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CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary by Yibo Xue, Brian Meehan, Elizabeth Macdonald, Sriram Venneti, Xue Qing D. Wang, Leora Witkowski, Petar Jelinic, Tim Kong, Daniel Martinez, Geneviève Morin, Michelle Firlit, Atefeh Abedini, Radia M. Johnson, Regina Cencic, Jay Patibandla, Hongbo Chen, Andreas I. Papadakis, Aurelie Auguste, Iris de Rink, Ron M. Kerkhoven, Nicholas Bertos, Walter H. Gotlieb, Blaise A. Clarke, Alexandra Leary, Michael Witcher, Marie-Christine Guiot, Jerry Pelletier, Josée Dostie, Morag Park, Alexander R. Judkins, Ralf Hass, Douglas A. Levine, Janusz Rak, Barbara Vanderhyden, William D. Foulkes, Sidong Huang

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