Novel functions of FoxM1: from molecular mechanisms to cancer therapy by Mónica eAlvarez-Fernández, René H Medema

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Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats by Daniël O. Warmerdam, Jeroen van den Berg, René H. Medema

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Balanced Activity of Three Mitotic Motors Is Required for Bipolar Spindle Assembly and Chromosome Segregation by Roy G.H.P. van Heesbeen, Marvin E. Tanenbaum, René H. Medema

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Combined Inactivation of Pocket Proteins and APC/C^Cdh1 by Cdk4/6 Controls Recovery from DNA Damage in G1 Phase by Indra A. Shaltiel, Alba Llopis, Melinda Aprelia, Rob Klompmaker, Apostolos Menegakis, Lenno Krenning, René H. Medema

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p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies by Mar Soto, Jonne A. Raaijmakers, Bjorn Bakker, Diana C.J. Spierings, Peter M. Lansdorp, Floris Foijer, René H. Medema

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Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells by Iraia García-Santisteban, Alba Llopis, Lenno Krenning, Jon Vallejo-Rodríguez, Bram van den Broek, Ana M. Zubiaga, René H. Medema

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Hypersensitivity to DNA damage in antephase as a safeguard for genome stability by Femke M. Feringa, Lenno Krenning, André Koch, Jeroen van den Berg, Bram van den Broek, Kees Jalink, René H. Medema

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Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. by Nannette Jelluma, Arjan B Brenkman, Ian McLeod, John R Yates, Don W Cleveland, René H Medema, Geert J P L Kops

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Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence by Apostolos Menegakis, Rob Klompmaker, Claire Vennin, Aina Arbusà, Maartje Damen, Bram van den Broek, Daniel Zips, Jacco van Rheenen, Lenno Krenning, René H. Medema

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BUB1 Is Essential for the Viability of Human Cells in which the Spindle Assembly Checkpoint Is Compromised by Jonne A. Raaijmakers, Roy G.H.P. van Heesbeen, Vincent A. Blomen, Louise M.E. Janssen, Ferdy van Diemen, Thijn R. Brummelkamp, René H. Medema

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Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1. by Renske van Leuken, Linda Clijsters, Wouter van Zon, Dan Lim, XueBiao Yao, Rob M F Wolthuis, Michael B Yaffe, René H Medema, Marcel A T M van Vugt

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The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability. by Dorine C Hintzen, Mar Soto, Michael Schubert, Bjorn Bakker, Diana C J Spierings, Karoly Szuhai, Peter M Lansdorp, Roel J C Kluin, Floris Foijer, René H Medema, Jonne A Raaijmakers

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MND1 enables homologous recombination in somatic cells primarily outside the context of replication by Lisa Koob, Anoek Friskes, Louise vanBergen, Femke M. Feringa, Bram van denBroek, Emma S. Koeleman, Ellis vanBeek, Michael Schubert, Vincent A. Blomen, Thijn R. Brummelkamp, Lenno Krenning, René H. Medema

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Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. by Daniël Splinter, Marvin E Tanenbaum, Arne Lindqvist, Dick Jaarsma, Annette Flotho, Ka Lou Yu, Ilya Grigoriev, Dieuwke Engelsma, Elize D Haasdijk, Nanda Keijzer, Jeroen Demmers, Maarten Fornerod, Frauke Melchior, Casper C Hoogenraad, René H Medema, Anna Akhmanova

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Degree and site of chromosomal instability define its oncogenic potential by Wilma H. M. Hoevenaar, Aniek Janssen, Ajit I. Quirindongo, Huiying Ma, Sjoerd J. Klaasen, Antoinette Teixeira, Bastiaan van Gerwen, Nico Lansu, Folkert H. M. Morsink, G. Johan A. Offerhaus, René H. Medema, Geert J. P. L. Kops, Nannette Jelluma

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Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity. by Ziva Pogacar, Jackie L Johnson, Lenno Krenning, Giulia De Conti, Fleur Jochems, Cor Lieftink, Arno Velds, Leyma Wardak, Kelvin Groot, Arnout Schepers, Liqin Wang, Ji-Ying Song, Marieke van de Ven, Olaf van Tellingen, Rene H Medema, Roderick L Beijersbergen, Rene Bernards, Rodrigo Leite de Oliveira

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Perturbations in 3D genome organization can promote acquired drug resistance by Anna G. Manjón, Stefano Giustino Manzo, Stefan Prekovic, Leon Potgeter, Tom van Schaik, Ning Qing Liu, Koen Flach, Daniel Peric-Hupkes, Stacey Joosten, Hans Teunissen, Anoek Friskes, Mila Ilic, Dorine Hintzen, Vinícius H. Franceschini-Santos, Wilbert Zwart, Elzo de Wit, Bas van Steensel, René H. Medema

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Mutations in LRRC50 predispose zebrafish and humans to seminomas. by Sander G Basten, Erica E Davis, Ad J M Gillis, Ellen van Rooijen, Hans Stoop, Nikolina Babala, Ive Logister, Zachary G Heath, Trudy N Jonges, Nicholas Katsanis, Emile E Voest, Freek J van Eeden, Rene H Medema, René F Ketting, Stefan Schulte-Merker, Leendert H J Looijenga, Rachel H Giles

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