Bosentan alleviates the pro-fibrotic phenotype of lung scleroderma fibroblasts: Implications for treatment of scleroderma. by Leask, A, Xu, S, Renzoni, E, Bou-Gharios, G, du Bois, R, Abraham, D, Black, C

Hammerhead ribozyme-mediated silencing of the mutant fibrillin-1 of tight skin mouse: insight into the functional role of mutant fibrillin-1. by Menon, R, Menon, MR, Shi-Wen, X, Renzoni, E, Bou-Gharios, G, Black, C, Abraham, D

Response of human lung fibroblast cells to stimulation by endothelin-1: Involvement of ras/MEK/ERK and PI3 kinase by Shiwen, X, Dashwood, MR, Denton, C, Renzoni, E, Bou-Gharios, G, du Bois, R, Leask, A, Abraham, D, Black, C

Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts. by Shi-wen, X, Kennedy, L, Renzoni, E, Bou-Gharios, G, du Bois, R, Black, C, Denton, C, Abraham, D, Leask, A

Bosentan attenuates the profibrotic gene expression profile of lung fibroblasts in scleroderma by Shiwen, X, Leask, A, Renzoni, E, Howat, S, Bou-Gharios, G, Pearson, J, du Bois, R, Denton, C, Abraham, D, Black, C

Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK. by Xu, S, Howat, S, Renzoni, E, Holmes, A, Pearson, J, Dashwood, MR, Bou-Gharios, G, Denton, C, du Bois, R, Black, C, Leask, A, Abraham, D

Novel transforming growth factor beta transcriptional targets in adult lung fibroblasts indentified by microarray analysis by Renzoni, E, Abraham, D, Shi-Wen, X, Howat, S, Bou-Gharios, G, Wells, A, Veeraraghavan, S, Nicholson, A, Denton, C, Pearson, J, Black, C, Welsh, K, du Bois, R

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile pheno... by Shi-Wen, X, Chen, Y, Denton, C, Eastwood, M, Renzoni, E, Bou-Gharios, G, Pearson, J, Dashwood, M, du Bois, R, Black, C, Leask, A, Abraham, D

Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts. by Shi-Wen, X, Renzoni, E, Kennedy, L, Howat, S, Chen, Y, Pearson, J, Bou-Gharios, G, Dashwood, MR, du Bois, R, Black, C, Denton, C, Abraham, D, Leask, A

Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into path... by Chen, Y, Shi-Wen, X, van Beek, J, Kennedy, L, McLeod, M, Renzoni, E, Bou-Gharios, G, Wilcox-Adelman, S, Goetinck, P, Eastwood, M, Black, C, Abraham, D, Leask, A

Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k). by Denton, C, Lindahl, G, Khan, K, Shiwen, X, Ong, V, Gaspar, N, Lazaridis, K, Edwards, DR, Leask, A, Eastwood, M, Leoni, P, Renzoni, E, Bou Gharios, G, Abraham, D, Black, C

Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. by Renzoni, E, Abraham, D, Howat, S, Shi-Wen, X, Sestini, P, Bou-Gharios, G, Wells, A, Veeraraghavan, S, Nicholson, A, Denton, C, Leask, A, Pearson, J, Black, C, Welsh, K, du Bois, R

CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. by Shi-wen, X, Stanton, L, Kennedy, L, Pala, D, Chen, Y, Howat, S, Renzoni, E, Carter, D, Bou-Gharios, G, Stratton, R, Pearson, J, Beier, F, Lyons, K, Black, C, Abraham, D, Leask, A