An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans 由 Repapi, E

CTAS - A CT score to quantify disease activity in pulmonary sarcoidosis 由 Ho, L, Benamore, R, Kendrick, Y, Repapi, E, Helm, E, Cole, S, Taylor, S

CTAS – a ct score to quantify disease activity in pulmonary sarcoidosis 由 Kendrick, Y, Repapi, E, Helm, E, Cole, S, Hoyles, R, Benamore, R, Ho, L

SCL establishes a transcriptional and epigenetic repressive environment in blood-fated cells to suppress alternative mesodermal lineages 由 Porcher, C, Chagraoui, H, Kristiansen, M, Richter, J, Gray, N, Repapi, E, Taylor, S, Vyas, P

No evidence for age-related differences in mtRNA quality in the female germline 由 Hartley, FM, Alageel, A, Appeltant, R, Gray, N, Repapi, E, Wells, D, Williams, SA, Poulton, J

Transforming Growth Factor β drives haemogenic endothelium programming and the transition to haematopoietic stem cells 由 Monteiro, R, Pinheiro, P, Joseph, N, Peterkin, T, Koth, J, Repapi, E, Bonkhofer, F, Kirmizitas, A, Patient, R

Reconstruction of the global neural crest gene regulatory network in vivo 由 Williams, R, Candido-Ferreira, I, Repapi, E, Gavriouchkina, D, Senanayake, U, Ling, I, Telenius, J, Taylor, S, Hughes, J, Sauka-Spengler, T

From pioneer to repressor: bimodal foxd3 activity dynamically remodels neural crest regulatory landscape in vivo 由 Lukoseviciute, M, Gavriouchkina, D, Williams, R, Hochgreb-Hagele, T, Senanayake, U, Chong-Morrison, V, Thongjuea, S, Repapi, E, Mead, A, Sauka-Spengler, T

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation. 由 Godfrey, L, Kerry, J, Thorne, R, Repapi, E, Davies, J, Tapia, M, Ballabio, E, Hughes, J, Geng, H, Konopleva, M, Milne, T

Single cell spatial analysis of lungs from patients with fatal COVID-19 reveals a cellular network marked by inflammatory foci of immature neutrophil and CD8 T cells localised to a... 由 Weeratunga, P, Denney, L, Bull, J, Repapi, E, Sergeant, M, Vuppusetty, C, C Cosmic Consortium, Byrne, H, Taylor, S, Ho, L-P

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort. 由 Zhang, Y, Makvandi-Nejad, S, Qin, L, Zhao, Y, Zhang, T, Wang, L, Repapi, E, Taylor, S, McMichael, A, Li, N, Dong, T, Wu, H

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells 由 Hardman, C, Chen, Y, Salimi, M, Jarrett, R, Johnson, D, Jarvinen, V, Owens, R, Repapi, E, Cousins, D, Barlow, J, McKenzie, A, Ogg, G

Disruption of haematopoietic stem cell heterogeniety in a mouse model of myelproliferate neoplasm 由 Norfo, R, Di Genua, C, Booth, C, Giustacchini, A, Povinelli, B, Gray, N, Repapi, E, Soilleux, E, Jamieson, L, Tran, N, Green, A, Jacobsen, S, Mead, A

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin 由 Truch, J, Downes, DJ, Scott, C, Gür, ER, Telenius, JM, Repapi, E, Schwessinger, R, Gosden, M, Brown, JM, Taylor, S, Cheong, PL, Hughes, JR, Higgs, DR, Gibbons, RJ

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation 由 Godfrey, L, Crump, N, Thorne, R, Lau, I, Repapi, E, Dimou, D, Smith, A, Harman, J, Telenius, J, Oudelaar, A, Downes, D, Vyas, P, Hughes, J, Milne, T

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide 由 Ramcharan, R, Petnga Kamdoum, W, Gao, S, Aleksic, T, Pfister, S, Tanner, J, Bridges, E, Asher, R, Watson, A, Margison, G, Woodcock, M, Repapi, E, Li, J, Middleton, M, Macaulay, V

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer. 由 Lenos, K, Grawenda, A, Lodder, K, Kuijjer, M, Teunisse, A, Repapi, E, Grochola, L, Bartel, F, Hogendoorn, P, Wuerl, P, Taubert, H, Cleton-Jansen, A, Bond, G, Jochemsen, A

IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent 由 Hardman, CS, Chen, Y-L, Salimi, M, Nahler, J, Corridoni, D, Jagielowicz, M, Chathuranga, F, Johnson, D, Repapi, E, Cousins, D, Barlow, J, McKenzie, A, Simmons, A, Ogg, G

Cell-Intrinsic Depletion of AML1-ETO-Positive Pre-Leukemic HSCs By Kras Activating Mutation 由 Di Genua, C, Norfo, R, Rodriguez-Meira, A, Drissen, R, Booth, C, Povinelli, B, Repapi, E, Gray, N, Carrelha, J, Kettyle, L, Jamieson, L, Neo, W, Nerlov, C, Mead, A

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 由 Kerry, J, Godfrey, L, Repapi, E, Tapia, M, Blackledge, N, Ma, H, Ballabio, E, O'Byrne, S, Ponthan, F, Heidenreich, O, Roy, A, Roberts, I, Konopleva, M, Klose, R, Geng, H, Milne, T