Editorial: Non-cutaneous melanoma: new therapeutic insights by Ernesto Rossi, Richard D. Carvajal

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Tebentafusp: T Cell Redirection for the Treatment of Metastatic Uveal Melanoma by Bertil E. Damato, Joseph Dukes, Howard Goodall, Richard D. Carvajal

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Treatment of uveal melanoma: where are we now? by Jessica Yang, Daniel K. Manson, Brian P. Marr, Richard D. Carvajal

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The reporting of uveal melanoma cases to the cancer registry in North Carolina by Kathleen G. Gordon, Richard D. Carvajal, Sharnee’ L. Graham, Odette M. Houghton

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Efficacy, Safety, and Tolerability of Approved Combination BRAF and MEK Inhibitor Regimens for <i>BRAF</i>-Mutant Melanoma by Omid Hamid, C. Lance Cowey, Michelle Offner, Mark Faries, Richard D. Carvajal

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Multiregional genetic evolution of metastatic uveal melanoma by Daniel A. Rodriguez, Jessica Yang, Michael A. Durante, Alexander N. Shoushtari, Stergios J. Moschos, Kazimierz O. Wrzeszczynski, J. William Harbour, Richard D. Carvajal

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Dose escalation results from a first-in-human, phase 1 study of glucocorticoid-induced TNF receptor–related protein agonist AMG 228 in patients with advanced solid tumors by Ben Tran, Richard D. Carvajal, Aurelien Marabelle, Sandip Pravin Patel, Patricia M. LoRusso, Erik Rasmussen, Gloria Juan, Vijay V. Upreti, Courtney Beers, Gataree Ngarmchamnanrith, Patrick Schöffski

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A phase Ib trial of combined PKC and MEK inhibition with sotrastaurin and binimetinib in patients with metastatic uveal melanoma by Sebastian Bauer, James Larkin, F. Stephen Hodi, Frank Stephen, Frank Stephen, Ellen H. W. Kapiteijn, Gary K. Schwartz, Emilano Calvo, Padmaja Yerramilli-Rao, Sophie Piperno-Neumann, Richard D. Carvajal

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Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma by Vivian Chua, Marlana Orloff, Jessica LF Teh, Takahito Sugase, Connie Liao, Timothy J Purwin, Bao Q Lam, Mizue Terai, Grazia Ambrosini, Richard D Carvajal, Gary Schwartz, Takami Sato, Andrew E Aplin

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Scoping review of genetic databases for rare dermatologic diseases: Opportunity for artificial intelligence and machine learning by Celine M. Schreidah, BS, George Bingham Reynolds, MS, Lauren M. Fahmy, BS, Richard D. Carvajal, MD, Maarten H. Vermeer, MD, Sean Whittaker, MD, Itsik Pe’er, PhD, Larisa J. Geskin, MD

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A Phase Ib Study of Sotrastaurin, a PKC Inhibitor, and Alpelisib, a PI3Kα Inhibitor, in Patients with Metastatic Uveal Melanoma by Alexander N. Shoushtari, Shaheer Khan, Kimberly Komatsubara, Lynn Feun, Nicolas Acquavella, Shahnaz Singh-Kandah, Tiffany Negri, Alexandra Nesson, Kelly Abbate, Serge Cremers, Elgilda Musi, Grazia Ambrosini, Shing Lee, Gary K. Schwartz, Richard D. Carvajal

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Intermittent MEK inhibition for the treatment of metastatic uveal melanoma by Shaheer Khan, Sapna P. Patel, Alexander N. Shoushtari, Grazia Ambrosini, Serge Cremers, Shing Lee, Lauren Franks, Shahnaz Singh-Kandah, Susana Hernandez, Naomi Sender, Kristina Vuolo, Alexandra Nesson, Prabhjot Mundi, Benjamin Izar, Gary K. Schwartz, Richard D. Carvajal

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Characterizing metastatic uveal melanoma patients who develop symptomatic brain metastases by Alexander Z. Wei, Matan Uriel, Agata Porcu, Michael P. Manos, Ann C. Mercurio, Michael M. Caplan, Liam Hulse, Rino S. Seedor, Marta Holovatska, Jasmine Francis, Shaheer A. Khan, Diana E. McDonnell, Dmitry Bogomolny, Takami Sato, Brian P. Marr, Rizwan Haq, Marlana Orloff, Alexander Shoushtari, Richard D. Carvajal

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Adjuvant crizotinib in high-risk uveal melanoma following definitive therapy by Shaheer Khan, Jose Lutzky, Alexander N. Shoushtari, Joanne Jeter, Brian Marr, Thomas E. Olencki, Colleen M. Cebulla, Mohamed Abdel-Rahman, J. William Harbour, Naomi Sender, Alexandra Nesson, Shahnaz Singh-Kandah, Susana Hernandez, Jeanelle King, Manpreet S. Katari, Lyssa Dimapanat, Stephanie Izard, Grazia Ambrosini, Oliver Surriga, Alex J. Rai, Codruta Chiuzan, Gary K. Schwartz, Richard D. Carvajal

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Perspectives in melanoma: meeting report from the “Melanoma Bridge” (December 5th–7th, 2019, Naples, Italy) by Paolo A. Ascierto, Igor Puzanov, Sanjiv S. Agarwala, Christian Blank, Richard D. Carvajal, Sandra Demaria, Reinhard Dummer, Marc Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Patrick Hwu, Roger S. Lo, Georgina V. Long, Jason J. Luke, Iman Osman, Michael A. Postow, Ryan J. Sullivan, Janis M. Taube, Giorgio Trinchieri, Hassane M. Zarour, Corrado Caracò, Magdalena Thurin

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy) by Paolo A. Ascierto, Sanjiv S. Agarwala, Christian Blank, Corrado Caracò, Richard D. Carvajal, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S. Lo, Amanda W. Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I. Poulikakos, Sergio A. Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, Magdalena Thurin

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A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies by Chia-Chi Lin, Elena Garralda, Patrick Schöffski, David S. Hong, Lillian L. Siu, Miguel Martin, Michela Maur, Rina Hui, Ross A Soo, Joanne Chiu, Tian Zhang, Brigette Ma, Chrisann Kyi, Daniel SW Tan, Philippe A. Cassier, John Sarantopoulos, Andrew Weickhardt, Richard D. Carvajal, Jennifer Spratlin, Taito Esaki, Fréderic Rolland, Wallace Akerley, Barbara Deschler-Baier, Lawrence Rispoli, Tanay S. Samant, Niladri Roy Chowdhury, Daniel Gusenleitner, Eunice L. Kwak, Vasileios Askoxylakis, Filippo De Braud

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Correction: Combination checkpoint blockade for metastatic cutaneous malignancies in kidney transplant recipients by Lisa Zimmer, Serigne Lo, Caroline Robert, John Haanen, Ines Pires da Silva, Reinhard Dummer, Michael Manos, Joanna Mangana, Marcus O Butler, Richard D Carvajal, Alon Vaisman, Christian Posch, F Stephen Hodi, Paola Queirolo, Axel Hauschild, Christian U Blank, Maria Grazia Vitale, Karijn P M Suijkerbuijk, Alexander M Menzies, Aljosja Rogiers, Chiara Tentori, Joseph M Grimes, Megan H Trager, Sharon Nahm, Peter Bowling, Neha Papneja, April A N Rose, Jessica S W Borgers, Severine Roy, Thiago Pimentel Muniz, Tim Cooksley, Jeremy Lupu, Samuel D Saibil, Michael Erdmann, Laura Pala, Ryan J Sullivan, Wilson H Miller Jr, Osama E Rahma, Paul C Lorigan

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Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition by Dirk Schadendorf, Carola Berking, Lisa Zimmer, Serigne Lo, Caroline Robert, John Haanen, Ines Pires da Silva, Paolo Antonio Ascierto, Reinhard Dummer, Michael Manos, Joanna Mangana, Marcus O Butler, Richard D Carvajal, Georgina V Long, Alon Vaisman, Christian Posch, F Stephen Hodi, Paola Queirolo, Axel Hauschild, Christian U Blank, Maria Grazia Vitale, Carlo Alberto Tondini, Leyre Zubiri, Arielle Elkrief, Karijn P M Suijkerbuijk, Mario Mandala, Alexander M Menzies, Aljosja Rogiers, Chiara Tentori, Joseph M Grimes, Megan H Trager, Sharon Nahm, Peter Bowling, Neha Papneja, April A N Rose, Jessica S W Borgers, Severine Roy, Thiago Pimentel Muniz, Tim Cooksley, Jeremy Lupu, Samuel D Saibil, Matteo S Carlino, Michael Erdmann, Laura Pala, Ryan J Sullivan, Wilson H Miller Jr, Kerry L Reynolds, Osama E Rahma, Paul C Lorigan

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