Unveiling the K+-sensitivity of cell metabolism using genetically encoded, FRET-based K+, glucose, and ATP biosensors by Helmut Bischof, Sandra Burgstaller, Wolfgang F. Graier, Robert Lukowski, Roland Malli

Get full text

Influence of the external breast prosthesis on the postural control of women who underwent mastectomy: Cross-sectional study by Anna Koralewska, Małgorzata Domagalska-Szopa, Robert Łukowski, Andrzej Szopa, Andrzej Szopa

Get full text

Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing by David Skrabak, Helmut Bischof, Thomas Pham, Peter Ruth, Rebekka Ehinger, Lucas Matt, Robert Lukowski

Get full text

Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea by Philine Marchetta, Philipp Eckert, Robert Lukowski, Peter Ruth, Wibke Singer, Lukas Rüttiger, Marlies Knipper

Get full text

Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE^−/− Mouse Model by Natalie Längst, Julia Adler, Anna Kuret, Andreas Peter, Peter Ruth, Karsten Boldt, Robert Lukowski

Get full text

Slack Potassium Channels Modulate TRPA1-Mediated Nociception in Sensory Neurons by Fangyuan Zhou, Katharina Metzner, Patrick Engel, Annika Balzulat, Marco Sisignano, Peter Ruth, Robert Lukowski, Achim Schmidtko, Ruirui Lu

Get full text

K_Ca3.1 Channels Confer Radioresistance to Breast Cancer Cells by Corinna J. Mohr, Dominic Gross, Efe C. Sezgin, Friederike A. Steudel, Peter Ruth, Stephan M. Huber, Robert Lukowski

Get full text

IKCa channels control breast cancer metabolism including AMPK-driven autophagy by Dominic Gross, Helmut Bischof, Selina Maier, Katharina Sporbeck, Andreas L. Birkenfeld, Roland Malli, Peter Ruth, Tassula Proikas-Cezanne, Robert Lukowski

Get full text

Cyclic GMP-Dependent Regulation of Vascular Tone and Blood Pressure Involves Cysteine-Rich LIM-Only Protein 4 (CRP4) by Natalie Längst, Julia Adler, Olga Schweigert, Felicia Kleusberg, Melanie Cruz Santos, Amelie Knauer, Matthias Sausbier, Tanja Zeller, Peter Ruth, Robert Lukowski

Get full text

Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing by Ruirui Lu, Katharina Metzner, Fangyuan Zhou, Cathrin Flauaus, Annika Balzulat, Patrick Engel, Jonas Petersen, Rebekka Ehinger, Anne Bausch, Peter Ruth, Robert Lukowski, Achim Schmidtko

Get full text

Cancer-Associated Intermediate Conductance Ca2+-Activated K+ Channel KCa3.1 by Corinna J. Mohr, Friederike A. Steudel, Dominic Gross, Peter Ruth, Wing-Yee Lo, Reiner Hoppe, Werner Schroth, Hiltrud Brauch, Stephan M. Huber, Robert Lukowski

Get full text

Monitoring extracellular ion and metabolite dynamics with recombinant nanobody-fused biosensors by Sandra Burgstaller, Teresa R. Wagner, Helmut Bischof, Sarah Bueckle, Aman Padamsey, Desiree Frecot, Philipp D. Kaiser, David Skrabak, Roland Malli, Robert Lukowski, Ulrich Rothbauer

Get full text

Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling by Dila Calis, Morgan Hess, Philine Marchetta, Wibke Singer, Julian Modro, Ellis Nelissen, Jos Prickaerts, Peter Sandner, Robert Lukowski, Peter Ruth, Marlies Knipper, Lukas Rüttiger

Get full text

Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia by Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev

Get full text

Stimulation of Slack K+ Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex by Matthew R. Fleming, Maile R. Brown, Jack Kronengold, Yalan Zhang, David P. Jenkins, Gulia Barcia, Rima Nabbout, Anne E. Bausch, Peter Ruth, Robert Lukowski, Dhasakumar S. Navaratnam, Leonard K. Kaczmarek

Get full text

SK4 channels modulate Ca2+ signalling and cell cycle progression in murine breast cancer by Friederike A. Steudel, Corinna J. Mohr, Benjamin Stegen, Hoang Y. Nguyen, Andrea Barnert, Marc Steinle, Sandra Beer‐Hammer, Pierre Koch, Wing‐Yee Lo, Werner Schroth, Reiner Hoppe, Hiltrud Brauch, Peter Ruth, Stephan M. Huber, Robert Lukowski

Get full text

Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo by Magdalena Bachmann, Andrea Rossa, Tatiana Varanita, Bernard Fioretti, Lucia Biasutto, Stefan Milenkovic, Vanessa Checchetto, Roberta Peruzzo, Syed A. Ahmad, Sameer H. Patel, Robert Lukowski, Michael J. Edwards, Matteo Ceccarelli, Erich Gulbins, Mario Zoratti, Andrea Mattarei, Ildiko Szabo

Get full text

Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine‐Independent and Chronic Itch by Annika Balzulat, W. Felix Zhu, Cathrin Flauaus, Victor Hernandez‐Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko

Get full text

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications by G. Todd Milne, on behalf of the Ironwood team, Peter Sandner, Kathleen A. Lincoln, Paul C. Harrison, Hongxing Chen, Hong Wang, Holly Clifford, Hu Sheng Qian, Diane Wong, Chris Sarko, Ryan Fryer, Jeremy Richman, Glenn A. Reinhart, Carine M. Boustany, Steven S. Pullen, Henriette Andresen, Lise Román Moltzau, Alessandro Cataliotti, Finn Olav Levy, Robert Lukowski, Sandra Frankenreiter, Andreas Friebe, Timothy Calamaras, Robert Baumgartner, Angela McLaughlin, Mark Aronovitz, Wendy Baur, Guang-Rong Wang, Navin Kapur, Richard Karas, Robert Blanton, Stefan Hell, Scott A. Waldman, Jieru E. Lin, Francheska Colon-Gonzalez, Gilbert W. Kim, Erik S. Blomain, Dante Merlino, Adam Snook, Jeanette Erdmann, Jana Wobst, Thorsten Kessler, Heribert Schunkert, Ulrich Walter, Oliver Pagel, Elena Walter, Stepan Gambaryan, Albert Smolenski, Kerstin Jurk, Rene Zahedi, James R. Klinger, Raymond L. Benza, Paul A. Corris, David Langleben, Robert Naeije, Gérald Simonneau, Christian Meier, Pablo Colorado, Mi Kyung Chang, Dennis Busse, Marius M. Hoeper, Jaime L. Masferrer, Sarah Jacobson, Guang Liu, Renee Sarno, Sylvie Bernier, Ping Zhang, G. Todd Milne, Roger Flores-Costa, Mark Currie, Katherine Hall, Dorit Möhrle, Katrin Reimann, Steffen Wolter, Markus Wolters, Evanthia Mergia, Nicole Eichert, Hyun-Soon Geisler, Peter Ruth, Andreas Friebe, Robert Feil, Ulrike Zimmermann, Doris Koesling, Marlies Knipper, Lukas Rüttiger, Yasutake Tanaka, Atsuko Okamoto, Takashi Nojiri, Motofumi Kumazoe, Takeshi Tokudome, Koichi Miura, Jun Hino, Hiroshi Hosoda, Mikiya Miyazato, Kenji Kangawa, Vikas Kapil, Amrita Ahluwalia, Nazareno Paolocci, Philip Eaton, James C. Campbell, Philipp Henning, Eugen Franz, Banumathi Sankaran, Friedrich W. Herberg, Choel Kim, M. Wittwer, Q. Luo, V. Kaila, S. A. Dames, Andrew Tobin, Mahmood Alam, Olena Rudyk, Susanne Krasemann, Kristin Hartmann, Oleksandra Prysyazhna, Min Zhang, Lan Zhao, Astrid Weiss, Ralph Schermuly, Philip Eaton, Amie J. Moyes, Sandy M. Chu, Reshma S. Baliga, Adrian J. Hobbs, Stylianos Michalakis, Regine Mühlfriedel, Christian Schön, Dominik M. Fischer, Barbara Wilhelm, Ditta Zobor, Susanne Kohl, Tobias Peters, Eberhart Zrenner, Karl Ulrich Bartz-Schmidt, Marius Ueffing, Bernd Wissinger, Mathias Seeliger, Martin Biel, RD-CURE consortium, Mark J. Ranek, Kristen M. Kokkonen, Dong I. Lee, Ronald J. Holewinski, Vineet Agrawal, Cornelia Virus, Donté A. Stevens, Masayuki Sasaki, Huaqun Zhang, Mathew M. Mannion, Peter P. Rainer, Richard C. Page, Jonathan C. Schisler, Jennifer E. Van Eyk, Monte S. Willis, David A. Kass, Manuela Zaccolo, Michael Russwurm, Jan Giesen, Corina Russwurm, Ernst-Martin Füchtbauer, Doris Koesling, Nadja I. Bork, Viacheslav O. Nikolaev, Luis Agulló, Martin Floor, Jordi Villà-Freixa, Ornella Manfra, Gaia Calamera, Nicoletta C. Surdo, Silja Meier, Alexander Froese, Viacheslav O. Nikolaev, Manuela Zaccolo, Finn Olav Levy, Kjetil Wessel Andressen, Annemarie Aue, Fabian Schwiering, Dieter Groneberg, Andreas Friebe, Gzona Bajraktari, Jürgen Burhenne, Walter E. Haefeli, Johanna Weiss, Katharina Beck, Barbara Voussen, Alexander Vincent, Sean P. Parsons, Jan D. Huizinga, Andreas Friebe, Fabiola Zakia Mónica, Edward Seto, Ferid Murad, Ka Bian, Joseph R. Burgoyne, Oleksandra Prysyazhna, Daniel Richards, Philip Eaton, Gaia Calamera, Marianne Bjørnerem, Andrea Hembre Ulsund, Jeong Joo Kim, Choel Kim, Finn Olav Levy, Kjetil Wessel Andressen, Sonia Donzelli, Mara Goetz, Kjestine Schmidt, Markus Wolters, Konstantina Stathopoulou, Oleksandra Prysyazhna, Jenna Scotcher, Christian Dees, Hariharan Subramanian, Elke Butt, Alisa Kamynina, S. Bruce King, Viacheslav O. Nikolaev, Cor de Witt, Lars I. Leichert, Robert Feil, Philip Eaton, Friederike Cuello, Hyazinth Dobrowinski, Moritz Lehners, Michael Paolillo Hannes Schmidt, Robert Feil, Susanne Feil, Lai Wen, Markus Wolters, Martin Thunemann, Kjestine Schmidt, Marcus Olbrich, Harald Langer, Meinrad Gawaz, Andreas Friebe, Cor de Wit, Robert Feil, Eugen Franz, Jeong Joo Kim, Daniela Bertinetti, Choel Kim, Friedrich W. Herberg, Hossein-Ardeschir Ghofrani, Friedrich Grimminger, Ekkehard Grünig, Yigao Huang, Pavel Jansa, Zhi Cheng Jing, David Kilpatrick, David Langleben, Stephan Rosenkranz, Flavia Menezes, Arno Fritsch, Sylvia Nikkho, Reiner Frey, Marc Humbert, Dieter Groneberg, Annemarie Aue, Fabian Schwiering, Andreas Friebe, Manuela Harloff, Joerg Reinders, Jens Schlossmann, Joon Jung, Jessica A. Wales, Cheng-Yu Chen, Linda Breci, Andrzej Weichsel, Sylvie G. Bernier, Robert Solinga, James E. Sheppeck, Paul A. Renhowe, William R. Montfort, Liying Qin, Ying-Ju Sung, Darren Casteel, Choel Kim, Alexander Kollau, Andrea Neubauer, Astrid Schrammel, Michael Russwurm, Doris Koesling, Bernd Mayer, Motofumi Kumazoe, Mika Takai, Chieri Takeuchi, Mai Kadomatsu, Shun Hiroi, Kanako Takamatsu, Takashi Nojiri, Kenji Kangawa, Hirofumi Tachibana, Marissa Opelt, Emrah Eroglu, Markus Waldeck-Weiermair, Michael Russwurm, Doris Koesling, Roland Malli, Wolfgang F. Graier, John T. Fassett, Astrid Schrammel, Bernd Mayer, Selene J. Sollie, Lise Román Moltzau, Maria Hernandez-Valladares, Frode Berven, Finn Olav Levy, Kjetil W. Andressen, Takashi Nojiri, Takeshi Tokudome, Motofumi Kumazoe, Miki Arai, Yutaka Suzuki, Koichi Miura, Jun Hino, Hiroshi Hosoda, Mikiya Miyazato, Meinoshin Okumura, Shinpei Kawaoka, Kenji Kangawa, Stefanie Peters, Hannes Schmidt, B. Selin Kenet, Sarah Helena Nies, Katharina Frank, Lai Wen, Fritz G. Rathjen, Robert Feil, Olga N. Petrova, Isabelle Lamarre, Michel Négrerie, Jerid W. Robinson, Jeremy R. Egbert, Julia Davydova, Laurinda A. Jaffe, Lincoln R. Potter, Jerid W. Robinson, Nicholas Blixt, Leia C. Shuhaibar, Gordon L. Warren, Kim C. Mansky, Laurinda A. Jaffe, Lincoln R. Potter, Simone Romoli, Tobias Bauch, Karoline Dröbner, Frank Eitner, Mihály Ruppert, Tamás Radovits, Sevil Korkmaz-Icöz, Shiliang Li, Péter Hegedűs, Sivakanan Loganathan, Balázs Tamás Németh, Attila Oláh, Csaba Mátyás, Kálmán Benke, Béla Merkely, Matthias Karck, Gábor Szabó, Ulrike Scheib, Matthias Broser, Shatanik Mukherjee, Katja Stehfest, Christine E. Gee, Heinz G. Körschen, Thomas G. Oertner, Peter Hegemann, Hannes Schmidt, Deborah M. Dickey, Alexandre Dumoulin, Ralf Kühn, Laurinda Jaffe, Lincoln R. Potter, Fritz G. Rathjen, Sophie Schobesberger, Peter Wright, Claire Poulet, Catherine Mansfield, Andreas Friebe, Sian E. Harding, Viacheslav O. Nikolaev, Julia Gorelik, Alexander Kollau, Marissa Opelt, Gerald Wölkart, Antonius C. F. Gorren, Michael Russwurm, Doris Koesling, Astrid Schrammel, Bernd Mayer, Gerburg K. Schwaerzer, Darren E. Casteel, Nancy D. Dalton, Yusu Gu, Shunhui Zhuang, Dianna M. Milewicz, Kirk L. Peterson, Renate Pilz, Fabian Schwiering, Annemarie Aue, Dieter Groneberg, Andreas Friebe, Aikaterini I. Argyriou, Garyfalia Makrynitsa, Ioannis I. Alexandropoulos, Andriana Stamopoulou, Marina Bantzi, Athanassios Giannis, Stavros Topouzis, Andreas Papapetropoulos, Georgios A. Spyroulias, Dennis J. Stuehr, Arnab Ghosh, Yue Dai, Saurav Misra, Boris Tchernychev, Joon Jung, Guang Liu, Inmaculada Silos-Santiago, Gerhard Hannig, Vu Thao-Vi Dao, Martin Deile, Pavel I. Nedvetsky, Andreas Güldner, César Ibarra-Alvarado, Axel Gödecke, Harald H. H. W. Schmidt, Angelos Vachaviolos, Andrea Gerling, Martin Thunemann, Stefan Z. Lutz, Hans-Ulrich Häring, Marcel A. Krüger, Bernd J. Pichler, Michael J. Shipston, Susanne Feil, Robert Feil, Sara Vandenwijngaert, Clara D. Ledsky, Obiajulu Agha, Dongjian Hu, Ibrahim J. Domian, Emmanuel S. Buys, Christopher Newton-Cheh, Donald B. Bloch, Barbara Voussen, Katharina Beck, Nadine Mauro, Jonas Keppler, Andreas Friebe, Wilson A. Ferreira, Hanan Chweih, Pamela L. Brito, Camila B. Almeida, Carla F. F. Penteado, Sara S. O. Saad, Fernando F. Costa, Paul S. Frenette, Damian Brockschnieder, Johannes-Peter Stasch, Peter Sandner, Nicola Conran, Daniel P. Zimmer, Jenny Tobin, Courtney Shea, Renee Sarno, Kimberly Long, Sarah Jacobson, Kim Tang, Peter Germano, James Wakefield, Ali Banijamali, G-Yoon Jamie Im, James E. Sheppeck, Albert T. Profy, G. Todd Milne, Mark G. Currie, Jaime L. Masferrer

Get full text