Conditionally Active, pH-Sensitive Immunoregulatory Antibodies Targeting VISTA and CTLA-4 Lead an Emerging Class of Cancer Therapeutics by F. Donelson Smith, Robert H. Pierce, Thomas Thisted, Edward H. van der Horst

Get full text

Durable tumor regression in highly refractory metastatic KIT/PDGFRA wild-type GIST following treatment with nivolumab by Brett A. Schroeder, Karan Kohli, Ryan B. O’Malley, Theresa S. Kim, Robin L. Jones, Robert H. Pierce, Seth M. Pollack

Get full text

Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma by Vladimir Makarov, Paul Nghiem, Jaehyuk Choi, Timothy A Chan, Kimberly S Smythe, Jean S Campbell, Robert H Pierce, Raphael Gottardo, Candice Church, David M Koelle, Thomas Pulliam, Natalie Longino, Song Y Park, Nadeem Riaz, Lichen Jing, Robert Amezquita

Get full text

Effects of HLA single chain trimer design on peptide presentation and stability by Kathryn A. K. Finton, Peter B. Rupert, Della J. Friend, Ana Dinca, Erica S. Lovelace, Matthew Buerger, Domnita V. Rusnac, Ulysses Foote-McNabb, William Chour, James R. Heath, Jean S. Campbell, Robert H. Pierce, Roland K. Strong

Get full text

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma by Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch, Garry P. Nolan

Get full text

Enhanced and sustained biodistribution of HIV-1 neutralizing antibody VRC01LS in human genital and rectal mucosa by Maria P. Lemos, Rena D. Astronomo, Yunda Huang, Sandeep Narpala, Madhu Prabhakaran, Philipp Mann, Carmen A. Paez, Yiwen Lu, Gregory J. Mize, Hayley Glantz, Katharine Westerberg, Hunter Colegrove, Kimberly S. Smythe, Minggang Lin, Robert H. Pierce, Julia Hutter, Ian Frank, John R. Mascola, Adrian B. McDermott, Linda-Gail Bekker, M. Juliana McElrath

Get full text

CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes by Seth M Pollack, Robin L Jones, Marissa Vignali, Brett A Schroeder, Shihong Zhang, Jose G Mantilla, Kimberly S Smythe, Jean S Campbell, Robert H Pierce, Lee D Cranmer, Michael J Wagner, Bonnie J LaFleur, Brian C Schulte, Natalie A LaFranzo, Rachel M Gittelman, Kevin C Flanagan, Julie Rytlewski, Laura Riolobos, Teresa S Kim, Eleanor Chen

Get full text

Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses by Michael C Jensen, Venu G Pillarisetty, Katherine J Brempelis, Courtney M Cowan, Shannon A Kreuser, Kevin P Labadie, Brooke M Prieskorn, Nicole A P Lieberman, Chibawanye I Ene, Kara W Moyes, Harrison Chinn, Kole R DeGolier, Lisa R Matsumoto, Sara K Daniel, Jason K Yokoyama, Amira D Davis, Virginia J Hoglund, Kimberly S Smythe, Stephanie D Balcaitis, Richard G Ellenbogen, Jean S Campbell, Robert H Pierce, Eric C Holland, Courtney A Crane

Get full text