Robert T. Sauer

Robert Thomas Sauer (born 13 July 1948) is an American biochemist who is the Salvador E. Luria Professor of Biology at the Massachusetts Institute of Technology. Provided by Wikipedia
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  1. 1
    The Non-dominant AAA+ Ring in the ClpAP Protease Functions as an Anti-stalling Motor to Accelerate Protein Unfolding and Translocation

    The Non-dominant AAA+ Ring in the ClpAP Protease Functions as an Anti-stalling Motor to Accelerate Protein Unfolding and Translocation by Hema Chandra Kotamarthi, Robert T. Sauer, Tania A. Baker

    Published 2020-02-01
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    Article
  2. 2
    Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding

    Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding by Tristan A Bell, Tania A Baker, Robert T Sauer

    Published 2019-06-01
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  3. 3
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates

    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates by Xue Fei, Tristan A Bell, Sarah R Barkow, Tania A Baker, Robert T Sauer

    Published 2020-10-01
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  4. 4
    ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP

    ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP by Sora Kim, Kristin L Zuromski, Tristan A Bell, Robert T Sauer, Tania A Baker

    Published 2020-12-01
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  5. 5
    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate

    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate by Xue Fei, Tristan A Bell, Simon Jenni, Benjamin M Stinson, Tania A Baker, Stephen C Harrison, Robert T Sauer

    Published 2020-02-01
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  6. 6
    Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

    Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens by Katherine Amberg-Johnson, Sanjay B Hari, Suresh M Ganesan, Hernan A Lorenzi, Robert T Sauer, Jacquin C Niles, Ellen Yeh

    Published 2017-08-01
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  7. 7
    Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease

    Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease by Meghann R. Kasal, Hema Chandra Kotamarthi, Madeline M. Johnson, Hannah M. Stephens, Matthew J. Lang, Robert T. Sauer, Tania A. Baker

    Published 2023-09-01
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  8. 8
    A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation

    A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation by Alireza Ghanbarpour, Steven E. Cohen, Xue Fei, Laurel F. Kinman, Tristan A. Bell, Jia Jia Zhang, Tania A. Baker, Joseph H. Davis, Robert T. Sauer

    Published 2023-11-01
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  9. 9
    Cooperativity and communication in archaeal Cdc48·20S, an ancient proteolytic machine

    Cooperativity and communication in archaeal Cdc48·20S, an ancient proteolytic machine by Grabenstatter, Jonathan Dean

    Published 2016
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  10. 10
    Identifying the requirement and mechanism of the dynamic yet kinetically stable ClpXP interface

    Identifying the requirement and mechanism of the dynamic yet kinetically stable ClpXP interface by Amor, Alvaro Jorge

    Published 2017
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  11. 11
    The role of hydrophobic core in protein folding

    The role of hydrophobic core in protein folding by Lim, Wendel Alan

    Published 2005
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  12. 12
    Identifying determinants of folding and activity for a protein of unknown structure

    Identifying determinants of folding and activity for a protein of unknown structure by Bowie, James Ulrich

    Published 2005
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  13. 13
    A genetic and biochemical analysis of the bacteriophage [lambda] cro protein

    A genetic and biochemical analysis of the bacteriophage [lambda] cro protein by Pakula, Andrew Arnold

    Published 2005
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  14. 14
    Role of communication between subunits and enzymes in ClpXP-mediated substrate unfolding and degradation

    Role of communication between subunits and enzymes in ClpXP-mediated substrate unfolding and degradation by Joshi, Shilpa Arun, 1975-

    Published 2005
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  15. 15
    Substrate denaturation and translocation by a proteolytic machine

    Substrate denaturation and translocation by a proteolytic machine by Kenniston, Jon Anders

    Published 2006
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  16. 16
    The engrailed homeodomain : determinants of DNA-binding affinity and specificity

    The engrailed homeodomain : determinants of DNA-binding affinity and specificity by Ades, Sarah Ellen

    Published 2006
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  17. 17
    β-sheet interactions with DNA revealed by the arc repressor-operator complex

    β-sheet interactions with DNA revealed by the arc repressor-operator complex by Raumann, Brigitte Elke

    Published 2006
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  18. 18
    P22 arc--energetics and cooperativity of DNA binding

    P22 arc--energetics and cooperativity of DNA binding by Brown, Bronwen Marylouise

    Published 2006
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  19. 19
    ClpX interactions with ClpP, SspB, protein substrate and nucleotide

    ClpX interactions with ClpP, SspB, protein substrate and nucleotide by Hersch, Greg Louis

    Published 2008
    Other Authors: “…Robert T. Sauer.…”
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    Thesis
  20. 20
    Specificity and regulation of substrate degradation for a AAA+ protease

    Specificity and regulation of substrate degradation for a AAA+ protease by Farrell, Christopher Mark

    Published 2007
    Other Authors: “…Robert T. Sauer.…”
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    Thesis

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