Editorial: The affective side of Alzheimer's disease (AD): neuropsychiatric symptoms as early sentinel of cognitive decline and pathogenetic factors in disease progression by Debora Cutuli, Debora Cutuli, Roberto Coccurello, Roberto Coccurello

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P2X7 Receptor in the Management of Energy Homeostasis: Implications for Obesity, Dyslipidemia, and Insulin Resistance by Roberto Coccurello, Roberto Coccurello, Cinzia Volonté, Cinzia Volonté

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The Endocannabinoids-Microbiota Partnership in Gut-Brain Axis Homeostasis: Implications for Autism Spectrum Disorders by Roberto Coccurello, Roberto Coccurello, Maria Cristina Marrone, Mauro Maccarrone, Mauro Maccarrone

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From the Gender Gap to Neuroactive Steroids: Exploring Multiple Cases to Further Understand Neuropathic Pain by Sara Marinelli, Roberto Coccurello

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A Step Forward: About the Progresses Made in the Second Edition of the Special Issue “The Multiple Mechanisms Underlying Neuropathic Pain” by Sara Marinelli, Roberto Coccurello

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Stimulation of P2X7 Enhances Whole Body Energy Metabolism in Mice by Giacomo Giacovazzo, Paola Fabbrizio, Savina Apolloni, Roberto Coccurello, Roberto Coccurello, Cinzia Volonté, Cinzia Volonté

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Alzheimer’s disease and depression in the elderly: A trajectory linking gut microbiota and serotonin signaling by Debora Cutuli, Debora Cutuli, Giacomo Giacovazzo, Davide Decandia, Davide Decandia, Roberto Coccurello, Roberto Coccurello

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Physical Exercise as Disease-Modifying Alternative against Alzheimer’s Disease: A Gut–Muscle–Brain Partnership by Debora Cutuli, Davide Decandia, Giacomo Giacovazzo, Roberto Coccurello

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Transcriptome Analysis in a Mouse Model of Premature Aging of Dentate Gyrus: Rescue of Alpha-Synuclein Deficit by Virus-Driven Expression or by Running Restores the Defective Neuro... by Laura Micheli, Teresa Maria Creanza, Manuela Ceccarelli, Giorgio D’Andrea, Giacomo Giacovazzo, Nicola Ancona, Roberto Coccurello, Roberto Coccurello, Raffaella Scardigli, Felice Tirone

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Lack of cyclin D3 induces skeletal muscle fiber-type shifting, increased endurance performance and hypermetabolism by Silvia Giannattasio, Giacomo Giacovazzo, Agnese Bonato, Carla Caruso, Siro Luvisetto, Roberto Coccurello, Maurizia Caruso

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Sex Differences in Neuropathy: The Paradigmatic Case of MetFormin by Federica De Angelis, Valentina Vacca, Jessica Tofanicchio, Georgios Strimpakos, Giacomo Giacovazzo, Flaminia Pavone, Roberto Coccurello, Sara Marinelli

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Sexually Dimorphic Immune and Neuroimmune Changes Following Peripheral Nerve Injury in Mice: Novel Insights for Gender Medicine by Valentina Vacca, Sara Marinelli, Federica De Angelis, Daniela F. Angelini, Eleonora Piras, Luca Battistini, Flaminia Pavone, Roberto Coccurello

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Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice. by Roberto Coccurello, Francesca Nazio, Claudia Rossi, Federica De Angelis, Valentina Vacca, Giacomo Giacovazzo, Patrizia Procacci, Valerio Magnaghi, Domenico Ciavardelli, Sara Marinelli

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Sex-specific adipose tissue’s dynamic role in metabolic and inflammatory response following peripheral nerve injury by Valentina Vacca, Claudia Rossi, Luisa Pieroni, Federica De Angelis, Giacomo Giacovazzo, Ilaria Cicalini, Domenico Ciavardelli, Flaminia Pavone, Roberto Coccurello, Sara Marinelli

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Fatty Acid Amide Hydrolase (FAAH) Inhibition Modulates Amyloid-Beta-Induced Microglia Polarization by Maddalena Grieco, Maria Giovanna De Caris, Elisa Maggi, Federica Armeli, Roberto Coccurello, Tiziana Bisogno, Maria D’Erme, Mauro Maccarrone, Patrizia Mancini, Rita Businaro

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Tau Cleavage Contributes to Cognitive Dysfunction in Strepto-Zotocin-Induced Sporadic Alzheimer’s Disease (sAD) Mouse Model by Valentina Latina, Giacomo Giacovazzo, Pietro Calissano, Anna Atlante, Federico La Regina, Francesca Malerba, Marco Dell’Aquila, Egidio Stigliano, Bijorn Omar Balzamino, Alessandra Micera, Roberto Coccurello, Giuseppina Amadoro

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Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease by Valentina Latina, Giacomo Giacovazzo, Federica Cordella, Bijorn Omar Balzamino, Alessandra Micera, Monica Varano, Cristina Marchetti, Francesca Malerba, Rita Florio, Bruno Bruni Ercole, Federico La Regina, Anna Atlante, Roberto Coccurello, Silvia Di Angelantonio, Pietro Calissano, Giuseppina Amadoro

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Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1G93A Mice Predates Disease Onset and Is A Promising Therapeutic Target by Silvia Scaricamazza, Illari Salvatori, Giacomo Giacovazzo, Jean Philippe Loeffler, Frederique Renè, Marco Rosina, Cyril Quessada, Daisy Proietti, Constantin Heil, Simona Rossi, Stefania Battistini, Fabio Giannini, Nila Volpi, Frederik J. Steyn, Shyuan T. Ngo, Elisabetta Ferraro, Luca Madaro, Roberto Coccurello, Cristiana Valle, Alberto Ferri

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Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease by Annalisa Nobili, Emanuele Claudio Latagliata, Maria Teresa Viscomi, Virve Cavallucci, Debora Cutuli, Giacomo Giacovazzo, Paraskevi Krashia, Francesca Romana Rizzo, Ramona Marino, Mauro Federici, Paola De Bartolo, Daniela Aversa, Maria Concetta Dell’Acqua, Alberto Cordella, Marco Sancandi, Flavio Keller, Laura Petrosini, Stefano Puglisi-Allegra, Nicola Biagio Mercuri, Roberto Coccurello, Nicola Berretta, Marcello D’Amelio

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