Exploiting Radiation Therapy to Restore Immune Reactivity of Glioblastoma ανά Mara De Martino, Oscar Padilla, Camille Daviaud, Cheng-Chia Wu, Cheng-Chia Wu, Robyn D. Gartrell, Claire Vanpouille-Box, Claire Vanpouille-Box

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Complete intracranial response to talimogene laherparepvec (T-Vec), pembrolizumab and whole brain radiotherapy in a patient with melanoma brain metastases refractory to dual checkp... ανά Zoë Blake, Douglas K. Marks, Robyn D. Gartrell, Thomas Hart, Patti Horton, Simon K. Cheng, Bret Taback, Basil A. Horst, Yvonne M. Saenger

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An open source automated tumor infiltrating lymphocyte algorithm for prognosis in melanoma ανά Balazs Acs, Fahad Shabbir Ahmed, Swati Gupta, Pok Fai Wong, Robyn D. Gartrell, Jaya Sarin Pradhan, Emanuelle M. Rizk, Bonnie Gould Rothberg, Yvonne M. Saenger, David L. Rimm

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Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker ανά Andrew X. Chen, Robyn D. Gartrell, Junfei Zhao, Pavan S. Upadhyayula, Wenting Zhao, Jinzhou Yuan, Hanna E. Minns, Athanassios Dovas, Jeffrey N. Bruce, Anna Lasorella, Antonio Iavarone, Peter Canoll, Peter A. Sims, Raul Rabadan

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Combining immunotherapy with high-dose radiation therapy (HDRT) significantly inhibits tumor growth in a syngeneic mouse model of high-risk neuroblastoma ανά Shuobo Boboila, Shunpei Okochi, Debarshi Banerjee, Sunjay Barton, Cherease Street, Ariela L. Zenilman, Qi Wang, Robyn D. Gartrell, Yvonne M. Saenger, David Welch, Cheng-Chia Wu, Angela Kadenhe-Chiweshe, Darrell J. Yamashiro, Eileen P. Connolly

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Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition ανά Jared M. Newton, Aurelie Hanoteau, Hsuan-Chen Liu, Angelina Gaspero, Falguni Parikh, Robyn D. Gartrell-Corrado, Thomas D. Hart, Damya Laoui, Jo A. Van Ginderachter, Neeraja Dharmaraj, William C. Spanos, Yvonne Saenger, Simon Young, Andrew G. Sikora

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Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway ανά Stuart P. Weisberg, Dustin J. Carpenter, Michael Chait, Pranay Dogra, Robyn D. Gartrell-Corrado, Andrew X. Chen, Sean Campbell, Wei Liu, Pooja Saraf, Mark E. Snyder, Masaru Kubota, Nichole M. Danzl, Beth A. Schrope, Raul Rabadan, Yvonne Saenger, Xiaojuan Chen, Donna L. Farber

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Focused ultrasound-mediated blood–brain barrier opening is safe and feasible with moderately hypofractionated radiotherapy for brainstem diffuse midline glioma ανά Masih Tazhibi, Nicholas McQuillan, Hong-Jian Wei, Matthew Gallitto, Ethan Bendau, Andrea Webster Carrion, Xander Berg, Danae Kokossis, Xu Zhang, Zhiguo Zhang, Chia-Ing Jan, Akiva Mintz, Robyn D. Gartrell, Hasan R. Syed, Adriana Fonseca, Jovana Pavisic, Luca Szalontay, Elisa E. Konofagou, Stergios Zacharoulis, Cheng-Chia Wu

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53 Inducing immune response with FLASH and conventional radiation in diffuse midline glioma (DMG) ανά Xu Zhang, Zhiguo Zhang, Raul Rabadan, Peter Canoll, Claire Vanpouille-Box, Hanna Minns, Oscar Padilla, Hong-Jian Wei, Robyn D Gartrell, Andrea Webster-Carrion, Masih Tazhibi, Nicholas McQuillan, Matthew Gallitto, Rebecca Yeh, Tom Hei, Luca Szalontay, Jovana Pavisic, Guy Garty, James Garvin, Vilas Menon, Marta Olah, Cheng-Chia Wu

Akt Inhibition Is Associated With Favorable Immune Profile Changes Within the Tumor Microenvironment of Hormone Receptor Positive, HER2 Negative Breast Cancer ανά Douglas K. Marks, Robyn D. Gartrell, Margueritta El Asmar, Shuobo Boboila, Thomas Hart, Yan Lu, Qingfei Pan, Jiyang Yu, Hanina Hibshoosh, Hanina Hibshoosh, Hua Guo, Eleni Andreopoulou, Lisa Wiechmann, Katherine Crew, Katherine Crew, Katherine Crew, Joseph Sparano, Dawn Hershman, Dawn Hershman, Dawn Hershman, Eileen Connolly, Yvonne Saenger, Yvonne Saenger, Kevin Kalinsky, Kevin Kalinsky

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Rare tumors: Opportunities and challenges from the Children’s Oncology Group perspective ανά Kris Ann P. Schultz, Murali Chintagumpala, Jin Piao, Kenneth S. Chen, Rachana Shah, Robyn D. Gartrell, Emily Christison-Lagay, Farzana Pashnakar, Jesse L. Berry, Allison F. O’Neill, Lauren M. Vasta, Ashley Flynn, Sarah G. Mitchell, Brittani KN. Seynnaeve, Jeremy Rosenblum, Samara L. Potter, Junne Kamihara, Carlos Rodriguez-Galindo, Douglas S. Hawkins, Theodore W. Laetsch

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Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy ανά Aurelie Hanoteau, Jared M. Newton, Rosemarie Krupar, Chen Huang, Hsuan-Chen Liu, Angelina Gaspero, Robyn D. Gartrell, Yvonne M. Saenger, Thomas D. Hart, Saskia J. Santegoets, Damya Laoui, Chad Spanos, Falguni Parikh, Padmini Jayaraman, Bing Zhang, Sjoerd H. Van der Burg, Jo A. Van Ginderachter, Cornelis J. M. Melief, Andrew G. Sikora

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Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma ανά Robyn D. Gartrell, Thomas Enzler, Pan S. Kim, Benjamin T. Fullerton, Ladan Fazlollahi, Andrew X. Chen, Hanna E. Minns, Subha Perni, Stuart P. Weisberg, Emanuelle M. Rizk, Samuel Wang, Eun Jeong Oh, Xinzheng V. Guo, Codruta Chiuzan, Gulam A. Manji, Susan E. Bates, John Chabot, Beth Schrope, Michael Kluger, Jean Emond, Raul Rabadán, Donna Farber, Helen E. Remotti, David P. Horowitz, Yvonne M. Saenger

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Automated digital TIL analysis (ADTA) adds prognostic value to standard assessment of depth and ulceration in primary melanoma ανά Michael R. Moore, Isabel D. Friesner, Emanuelle M. Rizk, Benjamin T. Fullerton, Manas Mondal, Megan H. Trager, Karen Mendelson, Ijeuru Chikeka, Tahsin Kurc, Rajarsi Gupta, Bethany R. Rohr, Eric J. Robinson, Balazs Acs, Rui Chang, Harriet Kluger, Bret Taback, Larisa J. Geskin, Basil Horst, Kevin Gardner, George Niedt, Julide T. Celebi, Robyn D. Gartrell-Corrado, Jane Messina, Tammie Ferringer, David L. Rimm, Joel Saltz, Jing Wang, Rami Vanguri, Yvonne M. Saenger

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