Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies by Anil P. S. Ori, Ake T. Lu, Steve Horvath, Roel A. Ophoff

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Correction: Investigation of the Genetic Association between Quantitative Measures of Psychosis and Schizophrenia: A Polygenic Risk Score Analysis. by Eske M. Derks, Jacob A. S. Vorstman, Stephan Ripke, Rene S. Kahn, Roel A. Ophoff

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An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging. by Tian Yuan, Yinming Jiao, Simone de Jong, Roel A Ophoff, Stephan Beck, Andrew E Teschendorff

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Sex-dependent novelty response in neurexin-1α mutant mice. by Marijke C Laarakker, Niels R Reinders, Hilgo Bruining, Roel A Ophoff, Martien J H Kas

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Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis. by Eske M Derks, Jacob A S Vorstman, Stephan Ripke, Rene S Kahn, Schizophrenia Psychiatric Genomic Consortium, Roel A Ophoff

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The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. by Marco P Boks, Eske M Derks, Daniel J Weisenberger, Erik Strengman, Esther Janson, Iris E Sommer, René S Kahn, Roel A Ophoff

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Powerful eQTL mapping through low-coverage RNA sequencing by Tommer Schwarz, Toni Boltz, Kangcheng Hou, Merel Bot, Chenda Duan, Loes Olde Loohuis, Marco P. Boks, René S. Kahn, Roel A. Ophoff, Bogdan Pasaniuc

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Hippocampal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice. by Simone de Jong, Martien J H Kas, Jeffrey Kiernan, Annetrude G de Mooij-van Malsen, Hugo Oppelaar, Esther Janson, Igor Vukobradovic, Charles R Farber, William L Stanford, Roel A Ophoff

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Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk by Anil P. S. Ori, Loes M. Olde Loohuis, Jerry Guintivano, Eilis Hannon, Emma Dempster, David St. Clair, Nick J. Bass, Andrew McQuillin, Jonathan Mill, Patrick F. Sullivan, Rene S. Kahn, Steve Horvath, Roel A. Ophoff

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Segment-wise genome-wide association analysis identifies a candidate region associated with schizophrenia in three independent samples. by Thomas E Gladwin, Eske M Derks, Genetic Risk and Outcome of Psychosis (GROUP), Marcella Rietschel, Manuel Mattheisen, René Breuer, Thomas G Schulze, Markus M Nöthen, Douglas Levinson, Jianxin Shi, Pablo V Gejman, Sven Cichon, Roel A Ophoff

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Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia by Loes M. Olde Loohuis, Serghei Mangul, Anil P. S. Ori, Guillaume Jospin, David Koslicki, Harry Taegyun Yang, Timothy Wu, Marco P. Boks, Catherine Lomen-Hoerth, Martina Wiedau-Pazos, Rita M. Cantor, Willem M. de Vos, René S. Kahn, Eleazar Eskin, Roel A. Ophoff

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A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes. by Simone de Jong, Marco P M Boks, Tova F Fuller, Eric Strengman, Esther Janson, Carolien G F de Kovel, Anil P S Ori, Nancy Vi, Flip Mulder, Jan Dirk Blom, Birte Glenthøj, Chris D Schubart, Wiepke Cahn, René S Kahn, Steve Horvath, Roel A Ophoff

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Genetic correlation between amyotrophic lateral sclerosis and schizophrenia by Russell L. McLaughlin, Dick Schijven, Wouter van Rheenen, Kristel R. van Eijk, Margaret O’Brien, René S. Kahn, Roel A. Ophoff, An Goris, Daniel G. Bradley, Ammar Al-Chalabi, Leonard H. van den Berg, Jurjen J. Luykx, Orla Hardiman, Jan H. Veldink, Project MinE GWAS Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium

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A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder. by Carla P D Fernandes, Andrea Christoforou, Sudheer Giddaluru, Kari M Ersland, Srdjan Djurovic, Manuel Mattheisen, Astri J Lundervold, Ivar Reinvang, Markus M Nöthen, Marcella Rietschel, Roel A Ophoff, Genetic Risk and Outcome of Psychosis (GROUP), Albert Hofman, André G Uitterlinden, Thomas Werge, Sven Cichon, Thomas Espeseth, Ole A Andreassen, Vidar M Steen, Stephanie Le Hellard

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Genetic and clinical analyses of psychosis spectrum symptoms in a large multiethnic youth cohort reveal significant link with ADHD by Loes M. Olde Loohuis, Eva Mennigen, Anil P. S. Ori, Diana Perkins, Elise Robinson, Jean Addington, Kristin S. Cadenhead, Barbara A. Cornblatt, Daniel H. Mathalon, Thomas H. McGlashan, Larry J. Seidman, Matcheri S. Keshavan, William S. Stone, Ming T. Tsuang, Elaine F. Walker, Scott W. Woods, Tyrone D. Cannon, Ruben C. Gur, Raquel E. Gur, Carrie E. Bearden, Roel A. Ophoff

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Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. by Jingyuan Fu, Marcel G M Wolfs, Patrick Deelen, Harm-Jan Westra, Rudolf S N Fehrmann, Gerard J Te Meerman, Wim A Buurman, Sander S M Rensen, Harry J M Groen, Rinse K Weersma, Leonard H van den Berg, Jan Veldink, Roel A Ophoff, Harold Snieder, David van Heel, Ritsert C Jansen, Marten H Hofker, Cisca Wijmenga, Lude Franke

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ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues by Serghei Mangul, Harry Taegyun Yang, Nicolas Strauli, Franziska Gruhl, Hagit T. Porath, Kevin Hsieh, Linus Chen, Timothy Daley, Stephanie Christenson, Agata Wesolowska-Andersen, Roberto Spreafico, Cydney Rios, Celeste Eng, Andrew D. Smith, Ryan D. Hernandez, Roel A. Ophoff, Jose Rodriguez Santana, Erez Y. Levanon, Prescott G. Woodruff, Esteban Burchard, Max A. Seibold, Sagiv Shifman, Eleazar Eskin, Noah Zaitlen

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Gene-network analysis identifies susceptibility genes related to glycobiology in autism. by Bert van der Zwaag, Lude Franke, Martin Poot, Ron Hochstenbach, Henk A Spierenburg, Jacob A S Vorstman, Emma van Daalen, Maretha V de Jonge, Nienke E Verbeek, Eva H Brilstra, Ruben van 't Slot, Roel A Ophoff, Michael A van Es, Hylke M Blauw, Jan H Veldink, Jacobine E Buizer-Voskamp, Frits A Beemer, Leonard H van den Berg, Cisca Wijmenga, Hans Kristian Ploos van Amstel, Herman van Engeland, J Peter H Burbach, Wouter G Staal

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Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. by Frank P Diekstra, Christiaan G J Saris, Wouter van Rheenen, Lude Franke, Ritsert C Jansen, Michael A van Es, Paul W J van Vught, Hylke M Blauw, Ewout J N Groen, Steve Horvath, Karol Estrada, Fernando Rivadeneira, Albert Hofman, Andre G Uitterlinden, Wim Robberecht, Peter M Andersen, Judith Melki, Vincent Meininger, Orla Hardiman, John E Landers, Robert H Brown, Aleksey Shatunov, Christopher E Shaw, P Nigel Leigh, Ammar Al-Chalabi, Roel A Ophoff, Leonard H van den Berg, Jan H Veldink

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. by Rudolf S N Fehrmann, Ritsert C Jansen, Jan H Veldink, Harm-Jan Westra, Danny Arends, Marc Jan Bonder, Jingyuan Fu, Patrick Deelen, Harry J M Groen, Asia Smolonska, Rinse K Weersma, Robert M W Hofstra, Wim A Buurman, Sander Rensen, Marcel G M Wolfs, Mathieu Platteel, Alexandra Zhernakova, Clara C Elbers, Eleanora M Festen, Gosia Trynka, Marten H Hofker, Christiaan G J Saris, Roel A Ophoff, Leonard H van den Berg, David A van Heel, Cisca Wijmenga, Gerard J Te Meerman, Lude Franke

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