PB2331: AN ONGOING FIRST-IN-HUMAN PHASE 1 TRIAL OF NX-5948, AN ORAL BRUTON’S TYROSINE KINASE (BTK) DEGRADER, IN PATIENTS WITH RELAPSED/REFRACTORY B CELL MALIGNANCIES by Kim Linton, Jeanette Doorduijn, Dima El-Sharkawi, Rogier Mous, Francesco Forconi, David Lewis, Mary Gleeson, John Riches, Pam Mckay, Wendy Stevens, Sarah G Injac, Graham P Collins

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P1159: INFERIOR OUTCOME OF FRAIL AND UNFIT PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA TREATED WITH ATTENUATED R-CHOP by Diana Al-Sarayfi, Mirian Brink, Martine E. D. Chamuleau, Rolf Brouwer, Roos van Rijn, Djamila Issa, Wendy Deenik, Gerwin Huls, Rogier Mous, Joost S.P. Vermaat, Josee M. Zijlstra, Tom van Meerten, Marcel Nijland

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S144: BTK AND BCL-2 ACTIVITY AT BASELINE PREDICTS MRD STATUS FOR CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS TREATED WITH IBRUTINIB + VENETOCLAX IN THE HOVON 141/VISION TRIAL by Aleksandra Urban, Johanne Hermansen, Yanping Yin, Weikaixin Kong, Rebecca Teglgaard, Christian Brieghel, Sabina Kersting, Geir E. Tjønnfjord, Mark-David Levin, Hoa T. T. Tran, Mattias Mattsson, Juha Ranti, Gerrit-Jan Veldhuis, Caspar Da Cunha-Bang, Rogier Mous, Julie Dubois, Arnon Kater, Carsten Niemann, Tero Aittokallio, Sigrid Skånland

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S148: TIME-LIMITED VENETOCLAX AND IBRUTINIB FOR PATIENTS WITH RELAPSED/REFRACTORY CLL WHO HAVE UNDETECTABLE MRD – 4-YEAR FOLLOW UP FROM THE RANDOMIZED PHASE II VISION/HO141 TRIAL by Arnon Kater, Julie Dubois, Christian Brieghel, Sabina Kersting, Lisbeth Enggaard, Gerrit Veldhuis, Rogier Mous, Clemens Mellink, Johan Dobber, Christian Poulsen, Caspar Da Cunha-Bang, Hendrik Fredriksen, Ann Janssens, Ida Schjodt, Ellen Dompeling, Juha Ranti, Mattias Mattsson, Mar Bellido, Hoa Tran, Kazem Nasserinejad, Mark-David Levin, Carsten Niemann

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A non-randomized risk-adjusted comparison of lenalidomide + R-CHOP versus R-CHOP for MYC-rearranged DLBCL patients by A. Vera de Jonge, Erik van Werkhoven, Avinash G. Dinmohamed, Marcel Nijland, Aeilko H. Zwinderman, Patrick M. Bossuyt, Martine S. Veldhuis, Emma G. G. M. Rutten, Rogier Mous, Joost S. P. Vermaat, Yorick Sandberg, Eva de Jongh, Yavuz M. Bilgin, Rinske Boersma, Harry Koene, Marie José Kersten, Daphne de Jong, Martine E. D. Chamuleau

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Genomic profiling of post-transplant lymphoproliferative disorders using cell-free DNA by Nick Veltmaat, Yujie Zhong, Filipe Montes de Jesus, Geok Wee Tan, Johanna A. A. Bult, Martijn M. Terpstra, Pim G. N. J. Mutsaers, Wendy B. C. Stevens, Rogier Mous, Joost S. P. Vermaat, Martine E. D. Chamuleau, Walter Noordzij, Erik A. M. Verschuuren, Klaas Kok, Joost L. Kluiver, Arjan Diepstra, Wouter J. Plattel, Anke van den Berg, Marcel Nijland

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Treatment of patients with MYC rearrangement positive large B-cell lymphoma with R-CHOP plus lenalidomide: results of a multicenter HOVON phase II trial by Martine E.D. Chamuleau, Coreline N. Burggraaff, Marcel Nijland, Katerina Bakunina, Rogier Mous, Pieternella J. Lugtenburg, Daan Dierickx, Gustaaf W. van Imhoff, Joost S.P. Vermaat, Erik A.F. Marijt, Otto Visser, Caroline Mandigers, Yavuz M. Bilgin, Aart Beeker, Mark F. Durian, Bas van Rees, Lara H. Bohmer, Lidwine W. Tick, Rinske S. Boersma, Tjeerd J.F. Snijders, Harry C. Schouten, Harry R. Koene, Eva de Jongh, Nathalie Hijmering, Arjan Diepstra, Anke van den Berg, Anne I.J. Arens, Julia Huijbregts, Otto Hoekstra, Josee M. Zijlstra, Daphne de Jong, Marie José Kersten

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The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants by Ana Rio-Machin, Tom Vulliamy, Nele Hug, Amanda Walne, Kiran Tawana, Shirleny Cardoso, Alicia Ellison, Nikolas Pontikos, Jun Wang, Hemanth Tummala, Ahad Fahad H. Al Seraihi, Jenna Alnajar, Findlay Bewicke-Copley, Hannah Armes, Michael Barnett, Adrian Bloor, Csaba Bödör, David Bowen, Pierre Fenaux, Andrew Green, Andrew Hallahan, Henrik Hjorth-Hansen, Upal Hossain, Sally Killick, Sarah Lawson, Mark Layton, Alison M. Male, Judith Marsh, Priyanka Mehta, Rogier Mous, Josep F. Nomdedéu, Carolyn Owen, Jiri Pavlu, Elspeth M. Payne, Rachel E. Protheroe, Claude Preudhomme, Nuria Pujol-Moix, Aline Renneville, Nigel Russell, Anand Saggar, Gabriela Sciuccati, David Taussig, Cynthia L. Toze, Anne Uyttebroeck, Peter Vandenberghe, Brigitte Schlegelberger, Tim Ripperger, Doris Steinemann, John Wu, Joanne Mason, Paula Page, Susanna Akiki, Kim Reay, Jamie D. Cavenagh, Vincent Plagnol, Javier F. Caceres, Jude Fitzgibbon, Inderjeet Dokal

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