“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance by Dario F. De Jesus, Rohit N. Kulkarni

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A Systematic Comparison of Protocols for Recovery of High-Quality RNA from Human Islets Extracted by Laser Capture Microdissection by Chiara M. A. Cefalo, Teresa Mezza, Andrea Giaccari, Rohit N. Kulkarni

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Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum by Adrian Kee Keong Teo, Ivan Achel Valdez, Ercument Dirice, Rohit N. Kulkarni

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Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance by Ercument Dirice, Giorgio Basile, Sevim Kahraman, Danielle Diegisser, Jiang Hu, Rohit N. Kulkarni

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Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation by Ivan Achel Valdez, Ercument Dirice, Manoj K. Gupta, Jun Shirakawa, Adrian Kee Keong Teo, Rohit N. Kulkarni

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Insulin signaling regulates mitochondrial function in pancreatic beta-cells. by Siming Liu, Terumasa Okada, Anke Assmann, Jamie Soto, Chong Wee Liew, Heiko Bugger, Orian S Shirihai, E Dale Abel, Rohit N Kulkarni

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Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses by Sevim Kahraman, Kimitaka Shibue, Dario F De Jesus, Hyunki Kim, Jiang Hu, Debasish Manna, Bridget Wagner, Amit Choudhary, Rohit N Kulkarni

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ROCK1 regulates insulin secretion from β-cells by Byung-Jun Sung, Sung-Bin Lim, Won-Mo Yang, Jae Hyeon Kim, Rohit N. Kulkarni, Young-Bum Kim, Moon-Kyu Lee

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Essential roles of insulin and IGF-1 receptors during embryonic lineage development by Erin R. Okawa, Manoj K. Gupta, Sevim Kahraman, Praneeth Goli, Masaji Sakaguchi, Jiang Hu, Kaiti Duan, Brittany Slipp, Jochen K. Lennerz, Rohit N. Kulkarni

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RADAR: differential analysis of MeRIP-seq data with a random effect model by Zijie Zhang, Qi Zhan, Mark Eckert, Allen Zhu, Agnieszka Chryplewicz, Dario F. De Jesus, Decheng Ren, Rohit N. Kulkarni, Ernst Lengyel, Chuan He, Mengjie Chen

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Maternal and paternal exercise regulate offspring metabolic health and beta cell phenotype by Ana Barbara Alves-Wagner, Kristin I Stanford, Noah B Prince, Kawai So, Joram D Mul, Ercument Dirice, Michael F Hirshman, Rohit N Kulkarni, Laurie J Goodyear

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Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation by Manoj K. Gupta, Dario F. De Jesus, Sevim Kahraman, Ivan A. Valdez, Farnaz Shamsi, Lian Yi, Adam C. Swensen, Yu-Hua Tseng, Wei-Jun Qian, Rohit N. Kulkarni

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Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas. by Garima Singhal, Ffolliott Martin Fisher, Melissa J Chee, Tze Guan Tan, Abdelfattah El Ouaamari, Andrew C Adams, Robert Najarian, Rohit N Kulkarni, Christophe Benoist, Jeffrey S Flier, Eleftheria Maratos-Flier

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Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States by Abdelfattah El Ouaamari, Dan Kawamori, Ercument Dirice, Chong Wee Liew, Jennifer L. Shadrach, Jiang Hu, Hitoshi Katsuta, Jennifer Hollister-Lock, Wei-Jun Qian, Amy J. Wagers, Rohit N. Kulkarni

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Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States by Abdelfattah El Ouaamari, Dan Kawamori, Ercument Dirice, Chong Wee Liew, Jennifer L. Shadrach, Jiang Hu, Hitoshi Katsuta, Jennifer Hollister-Lock, Wei-Jun Qian, Amy J. Wagers, Rohit N. Kulkarni

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The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes. by Gamze Kilic, Ana I Alvarez-Mercado, Bader Zarrouki, Darren Opland, Chong Wee Liew, Laura C Alonso, Martin G Myers, Jean-Christophe Jonas, Vincent Poitout, Rohit N Kulkarni, Franck Mauvais-Jarvis

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HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells by Natasha Hui Jin Ng, Joanita Binte Jasmen, Chang Siang Lim, Hwee Hui Lau, Vidhya Gomathi Krishnan, Juned Kadiwala, Rohit N. Kulkarni, Helge Ræder, Ludovic Vallier, Shawn Hoon, Adrian Kee Keong Teo

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Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells by Kanako Iwasaki, Kanako Iwasaki, Benjamin Lalani, Jiho Kahng, Priscila Carapeto, Stephanie Sanjines, Francesko Hela, Cristian Abarca, Tadataka Tsuji, Justin Darcy, Andrzej Bartke, Yu-Hua Tseng, Rohit N. Kulkarni, Cristina Aguayo-Mazzucato

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Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus. by Franco Folli, Terumasa Okada, Carla Perego, Jenny Gunton, Chong Wee Liew, Masaru Akiyama, Anna D'Amico, Stefano La Rosa, Claudia Placidi, Roberto Lupi, Piero Marchetti, Giorgio Sesti, Marc Hellerstein, Lucia Perego, Rohit N Kulkarni

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High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice by Tata Nageswara Rao, Jonathan Marks-Bluth, Jessica Sullivan, Manoj K. Gupta, Vashe Chandrakanthan, Simon R. Fitch, Katrin Ottersbach, Young C. Jang, Xianhua Piao, Rohit N. Kulkarni, Thomas Serwold, John E. Pimanda, Amy J. Wagers

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